2IUW

Crystal structure of human ABH3 in complex with iron ion and 2- oxoglutarate

Summary for 2IUW

Entry DOI	10.2210/pdb2iuw/pdb
Descriptor	ALKYLATED REPAIR PROTEIN ALKB HOMOLOG 3, FE (III) ION, 2-OXOGLUTARIC ACID, ... (5 entities in total)
Functional Keywords	oxidoreductase, dna/rna repair, demethylase, beta jellyroll
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	28377.34
Authors	Sundheim, O.,Vagbo, C.B.,Bjoras, M.,deSousa, M.M.L.,Talstad, V.,Aas, P.A.,Drablos, F.,Krokan, H.E.,Tainer, J.A.,Slupphaug, G. (deposition date: 2006-06-07, release date: 2006-07-26, Last modification date: 2019-05-22)
Primary citation	Sundheim, O.,Vagbo, C.B.,Bjoras, M.,Desousa, M.M.L.,Talstad, V.,Aas, P.A.,Drablos, F.,Krokan, H.E.,Tainer, J.A.,Slupphaug, G. Human Abh3 Structure and Key Residues for Oxidative Demethylation to Reverse DNA/RNA Damage. Embo J., 25:3389-, 2006 Cited by PubMed: 16858410 DOI: 10.1038/SJ.EMBOJ.7601219 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation