4NII

Crystal structure of AlkB D135I mutant protein with cofactors bound to dsDNA containing m6A/A

Summary for 4NII

• Entry DOI: 10.2210/pdb4nii/pdb
• Related: 4NID 4NIG 4NIH
• Descriptor: Alpha-ketoglutarate-dependent dioxygenase AlkB, 5'-D(*TP*AP*GP*GP*TP*AP*AP*(6MA)P*AP*CP*CP*GP*T)-3', 5'-D(*AP*AP*CP*GP*GP*TP*AP*TP*TP*AP*CP*CP*T)-3', ... (6 entities in total)
• Functional Keywords: dna/rna direct repair, jelly-roll fold, dna/rna demethylation repair, fe(ii), 2-kg, oxidoreductase-dna complex, oxidoreductase/dna
• Biological source: Escherichia coli
• Total number of polymer chains: 3
• Total formula weight: 31053.59

Authors

Yi, C.Q.,Zhu, C.X. (deposition date: 2013-11-06, release date: 2014-04-16, Last modification date: 2023-09-20)

• Primary citation: Zhu, C.,Yi, C.; Switching Demethylation Activities between AlkB Family RNA/DNA Demethylases through Exchange of Active-Site Residues.; Angew.Chem.Int.Ed.Engl., 53:3659-3662, 2014; PubMed: 24596302; DOI: 10.1002/anie.201310050

Experimental method

X-RAY DIFFRACTION (1.622 Å)