PDB: 45953 resultsInfo pagesStatus searchChemie searchBIRD

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2FIL	Crystal Structure Analysis of the A-DNA Decamer GCGT-2'OMeA-faT-ACGC, with Incorporated 2'-O-Methylated-Adenosine (2'OMeA) and 2'-Fluoroarabino-Thymidine (faT) Descriptor: 5'-D(*GP*CP*GP*TP*(A2M)P*(TAF)P*AP*CP*GP*C)-3', COBALT HEXAMMINE(III) Authors: Egli, M, Li, F. Deposit date: 2005-12-29 Release date: 2006-05-23 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.69 Å) Cite: 2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H. Biochemistry, 45, 2006
7YOZ	Cryo-EM structure of human subnucleosome (intermediate form) Descriptor: Histone H3.1, Histone H4, Widom601 DNA FW (145-MER), ... Authors: Nozawa, K, Takizawa, Y, Kurumizaka, H. Deposit date: 2022-08-02 Release date: 2022-11-16 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Cryo-electron microscopy structure of the H3-H4 octasome: A nucleosome-like particle without histones H2A and H2B. Proc.Natl.Acad.Sci.USA, 119, 2022
7N9H	Structure of the mammalian importin a1 bound to the TDP-43 NLS Descriptor: Importin subunit alpha-1, TAR DNA-binding protein 43 Authors: Doll, S.G, Lokareddy, R.K, Cingolani, G. Deposit date: 2021-06-17 Release date: 2022-06-22 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Recognition of the TDP-43 nuclear localization signal by importin alpha 1/ beta. Cell Rep, 39, 2022
5W7V	CryoEM structure of the segment, DLIIKGISVHI, assembled into a triple-helical fibril Descriptor: TAR DNA-binding protein 43 Authors: Guenther, E.L, Ge, P, Eisenberg, D.S. Deposit date: 2017-06-20 Release date: 2018-03-14 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2. Nat. Struct. Mol. Biol., 25, 2018
5WKB	MicroED structure of the segment, NFGEFS, from the A315E familial variant of the low complexity domain of TDP-43, residues 312-317 Descriptor: TAR DNA-binding protein 43 Authors: Guenther, E.L, Sawaya, M.R, Cascio, D, Eisenberg, D.S. Deposit date: 2017-07-24 Release date: 2018-05-23 Last modified: 2024-03-13 Method: ELECTRON CRYSTALLOGRAPHY (1 Å) Cite: Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
6JRF	Crystal structure of ZmMoc1-Holliday junction Complex in the presence of Calcium Descriptor: CALCIUM ION, DNA (33-MER), Monokaryotic chloroplast 1, ... Authors: Lin, Z, Lin, H, Zhang, D, Yuan, C. Deposit date: 2019-04-03 Release date: 2019-10-23 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.047 Å) Cite: Structural basis of sequence-specific Holliday junction cleavage by MOC1. Nat.Chem.Biol., 15, 2019
5WKD	Crystal structure of the segment, GNNQGSN, from the low complexity domain of TDP-43, residues 300-306 Descriptor: TAR DNA-binding protein 43 Authors: Guenther, E.L, Trinh, H, Sawaya, M.R, Cascio, D, Eisenberg, D.S. Deposit date: 2017-07-25 Release date: 2018-04-18 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
5WHP	Crystal structure of the segment, NFGTFS, from the A315T familial variant of the low complexity domain of TDP-43, residues 312-317 Descriptor: Segment of TAR DNA-binding protein 43 Authors: Guenther, E.L, Sawaya, M.R, Eisenberg, D.S. Deposit date: 2017-07-17 Release date: 2018-05-23 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1 Å) Cite: Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
5WIQ	Crystal structure of the segment, GFNGGFG, from the low complexity domain of TDP-43, residues 396-402 Descriptor: TAR DNA-binding protein 43 Authors: Guenther, E.L, Sawaya, M.R, Eisenberg, D.S. Deposit date: 2017-07-19 Release date: 2018-04-18 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
7X58	Cryo-EM structure of human subnucleosome (open form) Descriptor: Histone H3.1, Histone H4, Widom601 DNA FW (145-MER), ... Authors: Nozawa, K, Takizawa, Y, Kurumizaka, H. Deposit date: 2022-03-04 Release date: 2022-11-16 Last modified: 2024-06-26 Method: ELECTRON MICROSCOPY (3.93 Å) Cite: Cryo-electron microscopy structure of the H3-H4 octasome: A nucleosome-like particle without histones H2A and H2B. Proc.Natl.Acad.Sci.USA, 119, 2022
7X57	Cryo-EM structure of human subnucleosome (closed form) Descriptor: Histone H3.1, Histone H4, Widom601 DNA FW (145-MER), ... Authors: Nozawa, K, Takizawa, Y, Kurumizaka, H. Deposit date: 2022-03-04 Release date: 2022-11-16 Last modified: 2024-06-26 Method: ELECTRON MICROSCOPY (3.63 Å) Cite: Cryo-electron microscopy structure of the H3-H4 octasome: A nucleosome-like particle without histones H2A and H2B. Proc.Natl.Acad.Sci.USA, 119, 2022
5WHN	Crystal structure of the segment, NFGAFS, from the low complexity domain of TDP-43, residues 312-317 Descriptor: Segment of TAR DNA-binding protein 43 Authors: Guenther, E.L, Sawaya, M.R, Eisenberg, D.S. Deposit date: 2017-07-17 Release date: 2018-04-25 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.1 Å) Cite: Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
6E8D	Crystal structure of the Bacillus subtilis sliding clamp-MutL complex. Descriptor: Beta sliding clamp,DNA mismatch repair protein MutL, GLYCEROL Authors: Guarne, A, Almawi, A.W. Deposit date: 2018-07-28 Release date: 2019-05-01 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Binding of the regulatory domain of MutL to the sliding beta-clamp is species specific. Nucleic Acids Res., 47, 2019
1AY9	WILD-TYPE UMUD' FROM E. COLI Descriptor: UMUD PROTEIN Authors: Peat, T.S, Frank, E.G, Mcdonald, J.P, Levine, A.S, Woodgate, R, Hendrickson, W.A. Deposit date: 1997-11-15 Release date: 1998-01-28 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (3 Å) Cite: The UmuD' protein filament and its potential role in damage induced mutagenesis. Structure, 4, 1996
7AW4	MerTK kinase domain with type 3 inhibitor from a DNA-encoded library Descriptor: 1,2-ETHANEDIOL, 3-methyl-5-(4-methyl-1,2,3-thiadiazol-5-yl)-N-((R)-1-(((R)-3-(methylamino)-3-oxo-1-(4-(trifluoromethyl)phenyl)propyl)amino)-1-oxo-4-phenylbutan-2-yl)isoxazole-4-carboxamide, CHLORIDE ION, ... Authors: Pflug, A, Nissink, J.W.M, Blackett, C, Goldberg, K, Hennessy, E.J, Hardaker, E, McCoull, W, McMurray, L, Collingwood, O, Overman, R, Preston, M, Rawlins, P, Rivers, E, Schimpl, M, Smith, P, Underwood, E, Truman, C, Warwicker, J, Winter, J, Woodcock, S. Deposit date: 2020-11-06 Release date: 2021-03-03 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Generating Selective Leads for Mer Kinase Inhibitors-Example of a Comprehensive Lead-Generation Strategy. J.Med.Chem., 64, 2021
380D	BINDING OF THE MODIFIED DAUNORUBICIN WP401 ADJACENT TO A T-G BASE PAIR INDUCES THE REVERSE WATSON-CRICK CONFORMATION: CRYSTAL STRUCTURES OF THE WP401-TGGCCG AND WP401-CGG[BR5C]CG COMPLEXES Descriptor: 2'-BROMO-4'-EPIDAUNORUBICIN, DNA (5'-D(*CP*GP*(G49)P*(CBR)P*CP*G)-3') Authors: Dutta, R, Gao, Y.-G, Priebe, W, Wang, A.H.-J. Deposit date: 1998-02-18 Release date: 1998-07-13 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Binding of the modified daunorubicin WP401 adjacent to a T-G base pair induces the reverse Watson-Crick conformation: crystal structures of the WP401-TGGCCG and WP401-CGG[br5C]CG complexes. Nucleic Acids Res., 26, 1998
4DM0	TN5 transposase: 20MER OUTSIDE END 2 MN complex Descriptor: 1,2-ETHANEDIOL, DNA NON-TRANSFERRED STRAND, DNA TRANSFERRED STRAND, ... Authors: Klenchin, V.A, Lovell, S, Goryshin, I.Y, Reznikoff, W.R, Rayment, I. Deposit date: 2012-02-06 Release date: 2012-02-22 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Two-metal active site binding of a TN5 transposase synaptic complex Nat.Struct.Biol., 9, 2002
8DFA	type I-C Cascade bound to ssDNA target Descriptor: CRISPR-associated protein, CT1133 family, TM1801 family, ... Authors: O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W. Deposit date: 2022-06-21 Release date: 2023-02-22 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structural snapshots of R-loop formation by a type I-C CRISPR Cascade. Mol.Cell, 83, 2023
6AVK	Streptavidin bound to peptide-like compound KPM-6 Descriptor: 1-hydroxydodecan-4-one, N-[(2H-1,3-benzodioxol-5-yl)methyl]-2-({[(2H-1,3-benzodioxol-5-yl)methyl][2-(chloromethyl)-1,3-oxazole-4-carbonyl]amino}methyl)-N-[(4-carbamoyl-1,3-oxazol-2-yl)methyl]-1,3-oxazole-4-carboxamide, Streptavidin Authors: Park, H, Shamim, R, McEnaney, P, Kodadek, T. Deposit date: 2017-09-02 Release date: 2018-08-08 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Efficient Workflow for Screening DNA-encoded One Bead One Compound Libraries Using a Flow Cytometer To be Published
6CFH	SWGMMGMLASQ segment from the low complexity domain of TDP-43 Descriptor: TAR DNA-binding protein 43 Authors: Guenther, E.L, Rodriguez, J.A, Sawaya, M.R, Eisenberg, D.S. Deposit date: 2018-02-15 Release date: 2018-05-23 Last modified: 2024-05-15 Method: ELECTRON CRYSTALLOGRAPHY (1.5 Å) Cite: Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
3HO1	Crystal structure of T. thermophilus Argonaute N546 mutant protein complexed with DNA guide strand and 12-nt RNA target strand Descriptor: 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*T*AP*GP*T)-3', 5'-R(P*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*G)-3', MAGNESIUM ION, ... Authors: Wang, Y, Li, H, Sheng, G, Patel, D.J. Deposit date: 2009-06-01 Release date: 2009-10-06 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes. Nature, 461, 2009
7Y5W	Cryo-EM structure of the left-handed Di-tetrasome Descriptor: Histone H3.1, Histone H4, Widom 601 DNA (147-MER) Authors: Liu, C.P, Yu, Z.Y, Yu, C, Xu, R.M. Deposit date: 2022-06-17 Release date: 2023-08-16 Last modified: 2023-09-06 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Science, 381, 2023
2D1K	Ternary complex of the WH2 domain of mim with actin-dnase I Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... Authors: Chereau, D, Kerff, F, Dominguez, R. Deposit date: 2005-08-26 Release date: 2006-09-12 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural basis for the actin-binding function of missing-in-metastasis Structure, 15, 2007
5W7X	Crystal Structure of FHA domain of human APLF in complex with XRCC1 bisphospho peptide Descriptor: Aprataxin and PNK-like factor, DNA repair protein XRCC1 Authors: Pedersen, L.C, Kim, K, London, R.E. Deposit date: 2017-06-21 Release date: 2018-05-02 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.005 Å) Cite: Characterization of the APLF FHA-XRCC1 phosphopeptide interaction and its structural and functional implications. Nucleic Acids Res., 45, 2017
1H15	X-ray crystal structure of HLA-DRA1*0101/DRB5*0101 complexed with a peptide from Epstein Barr Virus DNA polymerase Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DNA POLYMERASE, ... Authors: Lang, H, Jacobsen, H, Ikemizu, S, Andersson, C, Harlos, K, Madsen, L, Hjorth, P, Sondergaard, L, Svejgaard, A, Wucherpfennig, K, Stuart, D.I, Bell, J.I, Jones, E.Y, Fugger, L. Deposit date: 2002-07-02 Release date: 2002-10-03 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (3.1 Å) Cite: A Functional and Structural Basis for Tcr Cross-Reactivity in Multiple Sclerosis Nat.Immunol., 3, 2002

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