PDB: 11109 resultsInfo pagesStatus searchChemie searchBIRD

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8TBB	F9S, novel TIM-3 targeting antibody, bound to IgV domain of TIM-3 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, F9S Fab heavy chain, F9S Fab light chain, ... Authors: Oganesyan, V, van Dyk, N, Mazor, Y, Yang, C. Deposit date: 2023-06-28 Release date: 2024-08-28 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Generation of AZD7789, a novel PD-1 and TIM-3 targeting bispecific antibody, which binds to a differentiated epitope of TIM-3 To be published
5UHT	Structure of the Thermotoga maritima HK853-BeF3-RR468 complex at pH 5.0 Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... Authors: Liu, Y, Rose, J, Jiang, L, Zhou, P. Deposit date: 2017-01-12 Release date: 2017-12-27 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.68 Å) Cite: A pH-gated conformational switch regulates the phosphatase activity of bifunctional HisKA-family histidine kinases. Nat Commun, 8, 2017
6YP9	Rabbit muscle actin in complex with ADF-H and ATP-ATTO-488 Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... Authors: Kogan, K, Kotila, T, Lappalainen, P. Deposit date: 2020-04-15 Release date: 2020-12-09 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.564 Å) Cite: A functional family of fluorescent nucleotide analogues to investigate actin dynamics and energetics. Nat Commun, 12, 2021
1H1C	Histidinol-phosphate aminotransferase (HisC) from Thermotoga maritima Descriptor: HISTIDINOL-PHOSPHATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE Authors: Vega, M.C, Fernandez, F.J, Wilmanns, M. Deposit date: 2002-07-08 Release date: 2004-03-19 Last modified: 2019-07-24 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Structural Studies of the Catalytic Reaction Pathway of a Hyperthermophilic Histidinol-Phosphate Aminotransferase J.Biol.Chem., 279, 2004
6NW5	Crystal structure of TmPep1050 aminopeptidase with its metal cofactors Descriptor: Aminopeptidase, COBALT (II) ION, HYDROXIDE ION, ... Authors: Dutoit, R. Deposit date: 2019-02-06 Release date: 2019-10-23 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.7 Å) Cite: How metal cofactors drive dimer-dodecamer transition of the M42 aminopeptidase TmPep1050 ofThermotoga maritima. J.Biol.Chem., 294, 2019
6WIB	Next generation monomeric IgG4 Fc Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin heavy constant gamma 4, ZINC ION Authors: Oganesyan, V.Y, Shan, L, Dall'Acqua, W, van Dyk, N. Deposit date: 2020-04-09 Release date: 2021-09-15 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.55 Å) Cite: In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance. Commun Biol, 4, 2021
6WMH	Next generation monomeric IgG4 Fc Descriptor: Immunoglobulin heavy constant gamma 4 Authors: Oganesyan, V.Y, Shan, L, van Dyk, N, Dall'Acqua, W.F. Deposit date: 2020-04-21 Release date: 2021-09-15 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.3 Å) Cite: In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance. Commun Biol, 4, 2021
6WNA	Next generation monomeric IgG4 Fc Descriptor: Beta-2-microglobulin, IgG receptor FcRn large subunit p51, Immunoglobulin heavy constant gamma 4, ... Authors: Oganesyan, V.Y, Shan, L, van Dyk, N, Dall'Acqua, W.F. Deposit date: 2020-04-22 Release date: 2021-09-15 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.4 Å) Cite: In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance. Commun Biol, 4, 2021
6WOL	Next generation monomeric IgG4 Fc bound to neonatal Fc receptor Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, IgG receptor FcRn large subunit p51, ... Authors: Oganesyan, V.Y, Shan, L, van Dyk, N, Dall'Acqua, W.F. Deposit date: 2020-04-24 Release date: 2021-09-15 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.49 Å) Cite: In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance. Commun Biol, 4, 2021
7UK2	Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with NN-390 Descriptor: Hdac6 protein, N-hydroxy-4-{[(propan-2-yl)(2,3,4,5-tetrafluorobenzene-1-sulfonyl)amino]methyl}benzamide, POTASSIUM ION, ... Authors: Erdogan, F, Seo, H.-S, Dhe-Paganon, S. Deposit date: 2022-03-31 Release date: 2022-11-02 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.6 Å) Cite: High Efficacy and Drug Synergy of HDAC6-Selective Inhibitor NN-429 in Natural Killer (NK)/T-Cell Lymphoma. Pharmaceuticals, 15, 2022
8CEE	Rnase R bound to a 30S degradation intermediate (State I - head-turning) Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... Authors: Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N. Deposit date: 2023-02-01 Release date: 2023-12-20 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural basis of ribosomal 30S subunit degradation by RNase R. Nature, 626, 2024
8CEC	Rnase R bound to a 30S degradation intermediate (State I - head-turning) Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... Authors: Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N. Deposit date: 2023-02-01 Release date: 2023-12-20 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.57 Å) Cite: Structural basis of ribosomal 30S subunit degradation by RNase R. Nature, 626, 2024
8CDU	Rnase R bound to a 30S degradation intermediate (main state) Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... Authors: Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N. Deposit date: 2023-02-01 Release date: 2023-12-20 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis of ribosomal 30S subunit degradation by RNase R. Nature, 626, 2024
8CED	Rnase R bound to a 30S degradation intermediate (State I - head-turning) Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... Authors: Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N. Deposit date: 2023-02-01 Release date: 2023-12-20 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (4.15 Å) Cite: Structural basis of ribosomal 30S subunit degradation by RNase R. Nature, 626, 2024
8CDV	Rnase R bound to a 30S degradation intermediate (state II) Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... Authors: Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N. Deposit date: 2023-02-01 Release date: 2023-12-20 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (4.73 Å) Cite: Structural basis of ribosomal 30S subunit degradation by RNase R. Nature, 626, 2024
1ILV	Crystal Structure Analysis of the TM107 Descriptor: STATIONARY-PHASE SURVIVAL PROTEIN SURE HOMOLOG Authors: Zhang, R, Joachimiak, A, Edwards, A, Savchenko, A, Beasley, S, Evdokimova, E, Midwest Center for Structural Genomics (MCSG) Deposit date: 2001-05-08 Release date: 2001-10-10 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of Thermotoga maritima stationary phase survival protein SurE: a novel acid phosphatase. Structure, 9, 2001
8Y7F	Crystal structure of CARF domain-truncated Csx1-Crn2 from Marinitoga sp. Descriptor: CRISPR-associated protein Authors: Zhang, D, Yuan, C, Lin, Z. Deposit date: 2024-02-04 Release date: 2024-07-17 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Structural insight into the Csx1-Crn2 fusion self-limiting ribonuclease of type III CRISPR system. Nucleic Acids Res., 52, 2024
8Y7G	Crystal structure of the Marinitoga sp. Csx1-Crn2 H495A mutant in complex with cyclic-tetraadenylate (cA4) Descriptor: ACETATE ION, CRISPR-associated protein, RNA (5'-R(P*AP*A)-3'), ... Authors: Zhang, D, Yuan, C, Lin, Z. Deposit date: 2024-02-04 Release date: 2024-07-17 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Structural insight into the Csx1-Crn2 fusion self-limiting ribonuclease of type III CRISPR system. Nucleic Acids Res., 52, 2024
8Y6Z	Crystal structure of the Marinitoga sp. Csx1-Crn2 fusion ribonuclease of type III CRISPR Descriptor: CRISPR-associated protein Authors: Zhang, D, Yuan, C. Deposit date: 2024-02-03 Release date: 2024-07-17 Last modified: 2024-08-21 Method: X-RAY DIFFRACTION (3.65 Å) Cite: Structural insight into the Csx1-Crn2 fusion self-limiting ribonuclease of type III CRISPR system. Nucleic Acids Res., 52, 2024
8Y75	Crystal structure of the CARF-HTH domain of Csx1-Crn2 from Marinitoga sp. Descriptor: CRISPR-associated protein Authors: Zhang, D, Yuan, C, Lin, Z. Deposit date: 2024-02-03 Release date: 2024-07-17 Last modified: 2024-08-21 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural insight into the Csx1-Crn2 fusion self-limiting ribonuclease of type III CRISPR system. Nucleic Acids Res., 52, 2024
5UAO	Crystal structure of MibH, a lathipeptide tryptophan 5-halogenase Descriptor: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Tryptophane-5-halogenase Authors: Cogan, D.P, Nair, S.K. Deposit date: 2016-12-19 Release date: 2017-01-25 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Two Flavoenzymes Catalyze the Post-Translational Generation of 5-Chlorotryptophan and 2-Aminovinyl-Cysteine during NAI-107 Biosynthesis. ACS Chem. Biol., 12, 2017
1GPW	Structural evidence for ammonia tunneling across the (beta/alpha)8 barrel of the imidazole glycerol phosphate synthase bienzyme complex. Descriptor: AMIDOTRANSFERASE HISH, HISF PROTEIN, PHOSPHATE ION Authors: Walker, M, Beismann-Driemeyer, S, Sterner, R, Wilmanns, M. Deposit date: 2001-11-12 Release date: 2002-02-10 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural Evidence for Ammonia Tunneling Across the (Beta Alpha)(8) Barrel of the Imidazole Glycerol Phosphate Synthase Bienzyme Complex. Structure, 10, 2002
5KBW	Crystal structure of TmRibU, the riboflavin-binding S subunit from the Thermotoga maritima ECF transporter Descriptor: RIBOFLAVIN, Riboflavin transporter RibU Authors: Karpowich, N.K, Wang, D.N, Song, J.M. Deposit date: 2016-06-03 Release date: 2016-06-29 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.6093 Å) Cite: An Aromatic Cap Seals the Substrate Binding Site in an ECF-Type S Subunit for Riboflavin. J.Mol.Biol., 428, 2016
5I4A	X-ray crystal structure of Marinitoga piezophila Argonaute in complex with 5' OH guide RNA Descriptor: Argonaute protein, RNA (5'-R(*UP*AP*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*U)-3') Authors: Doxzen, K.W, Kaya, E, Knoll, K.R, Wilson, R.C, Strutt, S.C, Kranzusch, P.J, Doudna, J.A. Deposit date: 2016-02-11 Release date: 2016-03-30 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.949 Å) Cite: A bacterial Argonaute with noncanonical guide RNA specificity. Proc.Natl.Acad.Sci.USA, 113, 2016
3PG8	Truncated form of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Thermotoga maritima Descriptor: AZIDE ION, GLYCEROL, Phospho-2-dehydro-3-deoxyheptonate aldolase Authors: Cross, P.J, Dobson, R.C.J, Patchett, M.L, Parker, E.J. Deposit date: 2010-10-31 Release date: 2011-01-26 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2 Å) Cite: Tyrosine latching of a regulatory gate affords allosteric control of aromatic amino acid biosynthesis J.Biol.Chem., 286, 2011

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