5UAO

Crystal structure of MibH, a lathipeptide tryptophan 5-halogenase

Summary for 5UAO

Entry DOI	10.2210/pdb5uao/pdb
Descriptor	Tryptophane-5-halogenase, FLAVIN-ADENINE DINUCLEOTIDE, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	halogenase, lanthipeptide, tryptophan, nai-107, oxidoreductase
Biological source	Microbispora sp. ATCC PTA-5024
Total number of polymer chains	4
Total formula weight	238593.90
Authors	Cogan, D.P.,Nair, S.K. (deposition date: 2016-12-19, release date: 2017-01-25, Last modification date: 2023-10-04)
Primary citation	Ortega, M.A.,Cogan, D.P.,Mukherjee, S.,Garg, N.,Li, B.,Thibodeaux, G.N.,Maffioli, S.I.,Donadio, S.,Sosio, M.,Escano, J.,Smith, L.,Nair, S.K.,van der Donk, W.A. Two Flavoenzymes Catalyze the Post-Translational Generation of 5-Chlorotryptophan and 2-Aminovinyl-Cysteine during NAI-107 Biosynthesis. ACS Chem. Biol., 12:548-557, 2017 Cited by PubMed: 28032983 DOI: 10.1021/acschembio.6b01031 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.88 Å)

Structure validation