8FFX
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![BU of 8ffx by Molmil](/molmil-images/mine/8ffx) | Crystal structure of HIV-1 reverse transcriptase in complex with non-nucleoside inhibitor 19980 | Descriptor: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Reverse transcriptase/ribonuclease H, ... | Authors: | Rumrill, S.R, Ruiz, F.X, Arnold, E. | Deposit date: | 2022-12-10 | Release date: | 2023-04-26 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Targeting HIV-1 Reverse Transcriptase Using a Fragment-Based Approach. Molecules, 28, 2023
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3INT
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![BU of 3int by Molmil](/molmil-images/mine/3int) | Structure of UDP-galactopyranose mutase bound to UDP-galactose (reduced) | Descriptor: | DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, GALACTOSE-URIDINE-5'-DIPHOSPHATE, Probable UDP-galactopyranose mutase, ... | Authors: | Gruber, T.D, Kiessling, L.L, Forest, K.T. | Deposit date: | 2009-08-12 | Release date: | 2009-09-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | X-ray crystallography reveals a reduced substrate complex of UDP-galactopyranose mutase poised for covalent catalysis by flavin . Biochemistry, 48, 2009
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5YKG
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![BU of 5ykg by Molmil](/molmil-images/mine/5ykg) | |
6MMG
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![BU of 6mmg by Molmil](/molmil-images/mine/6mmg) | Diheteromeric NMDA receptor GluN1/GluN2A in the '2-Knuckle-Symmetric' conformation, in complex with glycine and glutamate, in the presence of 1 millimolar EDTA, and at pH 7.4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | Authors: | Jalali-Yazdi, F, Chowdhury, S, Yoshioka, C, Gouaux, E. | Deposit date: | 2018-09-30 | Release date: | 2018-11-28 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (6.23 Å) | Cite: | Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor. Cell, 175, 2018
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3O1P
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![BU of 3o1p by Molmil](/molmil-images/mine/3o1p) | Iron-Catalyzed Oxidation Intermediates Captured in A DNA Repair Dioxygenase | Descriptor: | 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase AlkB, DNA (5'-D(*AP*AP*CP*GP*GP*TP*AP*TP*TP*AP*CP*CP*T)-3'), ... | Authors: | Yi, C, Jia, G, Hou, G, Dai, Q, Zhang, W, Zheng, G, Jian, X, Yang, C.-G, Cui, Q, He, C. | Deposit date: | 2010-07-21 | Release date: | 2010-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase. Nature, 468, 2010
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6MMX
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![BU of 6mmx by Molmil](/molmil-images/mine/6mmx) | Triheteromeric NMDA receptor GluN1/GluN2A/GluN2A* in the 'Extended' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | Authors: | Jalali-Yazdi, F, Chowdhury, S, Yoshioka, C, Gouaux, E. | Deposit date: | 2018-10-01 | Release date: | 2018-11-28 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (6.99 Å) | Cite: | Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor. Cell, 175, 2018
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3R85
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![BU of 3r85 by Molmil](/molmil-images/mine/3r85) | Crystal structure of human SOUL BH3 domain in complex with Bcl-xL | Descriptor: | Bcl-2-like protein 1, Heme-binding protein 2, SULFATE ION | Authors: | Ambrosi, E.K, Capaldi, S, Bovi, M, Saccomani, G, Perduca, M, Monaco, H.L. | Deposit date: | 2011-03-23 | Release date: | 2011-06-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural changes in the BH3 domain of SOUL protein upon interaction with the anti-apoptotic protein Bcl-xL. Biochem.J., 438, 2011
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6SPF
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![BU of 6spf by Molmil](/molmil-images/mine/6spf) | Pseudomonas aeruginosa 70s ribosome from an aminoglycoside resistant clinical isolate | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Halfon, Y, Jimenez-Fernande, A, La Ros, R, Espinos, R, Krogh Johansen, H, Matzov, D, Eyal, Z, Bashan, A, Zimmerman, E, Belousoff, M, Molin, S, Yonath, A. | Deposit date: | 2019-09-01 | Release date: | 2019-10-23 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate. Proc.Natl.Acad.Sci.USA, 116, 2019
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6MP6
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![BU of 6mp6 by Molmil](/molmil-images/mine/6mp6) | Cryo-EM structure of the human neutral amino acid transporter ASCT2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Neutral amino acid transporter B(0) | Authors: | Yu, X, Han, S. | Deposit date: | 2018-10-05 | Release date: | 2019-11-06 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Cryo-EM structures of the human glutamine transporter SLC1A5 (ASCT2) in the outward-facing conformation. Elife, 8, 2019
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3IPO
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![BU of 3ipo by Molmil](/molmil-images/mine/3ipo) | Crystal structure of YnjE | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, GLYCEROL, ... | Authors: | Haenzelmann, P, Kuper, J, Schindelin, H. | Deposit date: | 2009-08-18 | Release date: | 2009-12-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of YnjE from Escherichia coli, a sulfurtransferase with three rhodanese domains. Protein Sci., 18, 2009
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3RDJ
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![BU of 3rdj by Molmil](/molmil-images/mine/3rdj) | Rat PKC C2 domain Apo | Descriptor: | Protein kinase C alpha type | Authors: | Li, P. | Deposit date: | 2011-04-01 | Release date: | 2011-09-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Pb2+ as modulator of protein-membrane interactions. J.Am.Chem.Soc., 133, 2011
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3RDS
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![BU of 3rds by Molmil](/molmil-images/mine/3rds) | Crystal structure of the refolded R7-2 streptavidin | Descriptor: | PENTAETHYLENE GLYCOL, Streptavidin | Authors: | Malashkevich, V.N, Magalhaes, M, Czecster, C.M, Guan, R, Levy, M, Almo, S.C. | Deposit date: | 2011-04-01 | Release date: | 2011-07-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Evolved streptavidin mutants reveal key role of loop residue in high-affinity binding. Protein Sci., 20, 2011
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6SHJ
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![BU of 6shj by Molmil](/molmil-images/mine/6shj) | Escherichia coli AGPase in complex with FBP. Symmetry applied C2 | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, Glucose-1-phosphate adenylyltransferase | Authors: | Cifuente, J.O, Comino, N, D'Angelo, C, Marina, A, Gil-Carton, D, Albesa-Jove, D, Guerin, M.E. | Deposit date: | 2019-08-07 | Release date: | 2020-02-05 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | The allosteric control mechanism of bacterial glycogen biosynthesis disclosed by cryoEM. Curr Res Struct Biol, 2, 2020
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6MSM
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![BU of 6msm by Molmil](/molmil-images/mine/6msm) | Phosphorylated, ATP-bound human cystic fibrosis transmembrane conductance regulator (CFTR) | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ... | Authors: | Zhang, Z, Liu, F, Chen, J. | Deposit date: | 2018-10-16 | Release date: | 2018-11-21 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Molecular structure of the ATP-bound, phosphorylated human CFTR. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3VXD
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![BU of 3vxd by Molmil](/molmil-images/mine/3vxd) | Crystal structure of unsaturated glucuronyl hydrolase mutant D115N from Streptcoccus agalactiae | Descriptor: | Putative uncharacterized protein gbs1889, SULFATE ION | Authors: | Nakamichi, Y, Maruyama, Y, Mikami, B, Hashimoto, W, Murata, K. | Deposit date: | 2012-09-11 | Release date: | 2012-10-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of unsaturated glucuronyl hydrolase mutant D115N from Streptcoccus agalactiae To be Published
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6S8V
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![BU of 6s8v by Molmil](/molmil-images/mine/6s8v) | Structure of the high affinity Anticalin P3D11 in complex with the human CD98 heavy chain ectodomain | Descriptor: | 1,2-ETHANEDIOL, 4F2 cell-surface antigen heavy chain, Neutrophil gelatinase-associated lipocalin | Authors: | Schiefner, A, Deuschle, F.-C, Skerra, A. | Deposit date: | 2019-07-10 | Release date: | 2020-03-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Development of a high affinity Anticalin®directed against human CD98hc for theranostic applications. Theranostics, 10, 2020
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6MT7
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![BU of 6mt7 by Molmil](/molmil-images/mine/6mt7) | |
6MTF
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![BU of 6mtf by Molmil](/molmil-images/mine/6mtf) | D7 protein from Phlebotomus duboscqi, native | Descriptor: | 26.7 kDa salivary protein, FRAGMENT OF TRITON X-100 | Authors: | Andersen, J.F, Jablonka, W. | Deposit date: | 2018-10-19 | Release date: | 2019-04-10 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Functional and structural similarities of D7 proteins in the independently-evolved salivary secretions of sand flies and mosquitoes. Sci Rep, 9, 2019
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3VZJ
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![BU of 3vzj by Molmil](/molmil-images/mine/3vzj) | Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) E172H mutant | Descriptor: | Endo-1,4-beta-xylanase, SULFATE ION | Authors: | Ludwiczek, M.L, D'Angelo, I, Yalloway, G.N, Okon, M, Nielsen, J.E, Strynadka, N.C, Withers, S.G, McIntosh, L.P. | Deposit date: | 2012-10-14 | Release date: | 2013-05-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.406 Å) | Cite: | Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase Biochemistry, 52, 2013
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3VZM
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![BU of 3vzm by Molmil](/molmil-images/mine/3vzm) | Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) E172H mutant with Glu78 covalently bonded to 2-deoxy-2-fluoro-xylobiose | Descriptor: | Endo-1,4-beta-xylanase, beta-D-xylopyranose-(1-4)-1,5-anhydro-2-deoxy-2-fluoro-D-xylitol | Authors: | Ludwiczek, M.L, D'Angelo, I, Yalloway, G.N, Okon, M, Nielsen, J.E, Strynadka, N.C, Withers, S.G, McIntosh, L.P. | Deposit date: | 2012-10-15 | Release date: | 2013-05-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase Biochemistry, 52, 2013
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3REQ
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![BU of 3req by Molmil](/molmil-images/mine/3req) | |
8FDW
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![BU of 8fdw by Molmil](/molmil-images/mine/8fdw) | Cryo-EM structure of SARS-CoV-2 postfusion spike in membrane | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2, ... | Authors: | Zhang, J, Shi, W, Cai, Y.F, Zhu, H.S, Peng, H.Q, Voyer, J, Volloch, S.R, Cao, H, Mayer, M.L, Song, K.K, Xu, C, Lu, J.M, Chen, B. | Deposit date: | 2022-12-05 | Release date: | 2023-05-10 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Cryo-EM structure of SARS-CoV-2 postfusion spike in membrane. Nature, 619, 2023
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3IBT
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![BU of 3ibt by Molmil](/molmil-images/mine/3ibt) | Structure of 1H-3-hydroxy-4-oxoquinoline 2,4-dioxygenase (QDO) | Descriptor: | 1H-3-hydroxy-4-oxoquinoline 2,4-dioxygenase | Authors: | Oakley, A.J. | Deposit date: | 2009-07-16 | Release date: | 2010-02-02 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for cofactor-independent dioxygenation of N-heteroaromatic compounds at the alpha/beta-hydrolase fold. Proc.Natl.Acad.Sci.USA, 107, 2010
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4C69
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![BU of 4c69 by Molmil](/molmil-images/mine/4c69) | ATP binding to murine voltage-dependent anion channel 1 (mVDAC1). | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-TRIPHOSPHATE, LAURYL DIMETHYLAMINE-N-OXIDE, ... | Authors: | Paz, A, Colletier, J.P, Abramson, J. | Deposit date: | 2013-09-17 | Release date: | 2014-06-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.277 Å) | Cite: | Structure-Guided Simulations Illuminate the Mechanism of ATP Transport Through Vdac1. Nat.Struct.Mol.Biol., 21, 2014
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3RGS
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![BU of 3rgs by Molmil](/molmil-images/mine/3rgs) | |