3R85

Crystal structure of human SOUL BH3 domain in complex with Bcl-xL

Summary for 3R85

• Entry DOI: 10.2210/pdb3r85/pdb
• Related: 3R8J 3R8K
• Descriptor: Bcl-2-like protein 1, Heme-binding protein 2, SULFATE ION, ... (4 entities in total)
• Functional Keywords: bcl-2-like protein, inhibitor of cell death, soul protein, apoptosis
• Biological source: Homo sapiens; More
• Cellular location: Isoform Bcl-X(L): Mitochondrion inner membrane : Q07817; Cytoplasm : Q9Y5Z4
• Total number of polymer chains: 8
• Total formula weight: 83112.45

Authors

Ambrosi, E.K.,Capaldi, S.,Bovi, M.,Saccomani, G.,Perduca, M.,Monaco, H.L. (deposition date: 2011-03-23, release date: 2011-06-29, Last modification date: 2023-09-13)

• Primary citation: Ambrosi, E.,Capaldi, S.,Bovi, M.,Saccomani, G.,Perduca, M.,Monaco, H.L.; Structural changes in the BH3 domain of SOUL protein upon interaction with the anti-apoptotic protein Bcl-xL.; Biochem.J., 438:291-301, 2011; PubMed: 21639858; DOI: 10.1042/BJ20110257

Experimental method

X-RAY DIFFRACTION (1.95 Å)