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4WS4
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BU of 4ws4 by Molmil
Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with 5-nitrouracil, Form I
Descriptor: 5-nitrouracil, CHLORIDE ION, CITRIC ACID, ...
Authors:Arif, S.M, Geethanandan, K, Mishra, P, Surolia, A, Varshney, U, Vijayan, M.
Deposit date:2014-10-25
Release date:2015-07-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:Structural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implications.
Acta Crystallogr.,Sect.D, 71, 2015
6QEA
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BU of 6qea by Molmil
The X-ray structure of the adduct formed in the reaction between hen egg white lysozyme and complex I, a pentacoordinate Pt(II) compound containing 2,9-dimethyl-1,10-phenanthroline, dimethylfumarate, methyl and iodine as ligands
Descriptor: DIMETHYL SULFOXIDE, Lysozyme C, NITRATE ION, ...
Authors:Merlino, A, Ferraro, G.
Deposit date:2019-01-07
Release date:2019-03-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Reaction with Proteins of a Five-Coordinate Platinum(II) Compound.
Int J Mol Sci, 20, 2019
6QE9
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BU of 6qe9 by Molmil
The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and complex I, a pentacoordinate Pt(II) compound containing 2,9-dimethyl-1,10-phenanthroline, dimethylfumarate, methyl and iodine as ligands
Descriptor: Ribonuclease pancreatic, SULFATE ION, pentacoordinate Pt(II) compound
Authors:Merlino, A, Ferraro, G.
Deposit date:2019-01-07
Release date:2019-02-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Reaction with Proteins of a Five-Coordinate Platinum(II) Compound.
Int J Mol Sci, 20, 2019
5NSF
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BU of 5nsf by Molmil
Structure of AzuAla
Descriptor: (2~{S})-2-azanyl-3-(2,6-dihydroazulen-1-yl)propanoic acid, CALCIUM ION, GLYCEROL, ...
Authors:Martins, B.M.
Deposit date:2017-04-26
Release date:2019-01-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.426 Å)
Cite:Site-Resolved Observation of Vibrational Energy Transfer Using a Genetically Encoded Ultrafast Heater.
Angew. Chem. Int. Ed. Engl., 58, 2019
6HCV
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BU of 6hcv by Molmil
Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with a chromone ligand
Descriptor: 6-fluoranyl-~{N}-[(1-oxidanylcyclohexyl)methyl]-4-oxidanylidene-chromene-2-carboxamide, Lysine--tRNA ligase
Authors:Robinson, D.A, Baragana, B, Norcross, N, Forte, B, Walpole, C, Gilbert, I.H.
Deposit date:2018-08-16
Release date:2019-04-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Proc.Natl.Acad.Sci.USA, 116, 2019
4WRU
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BU of 4wru by Molmil
Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with uracil, Form II
Descriptor: CHLORIDE ION, GLYCEROL, URACIL, ...
Authors:Arif, S.M, Geethanandan, K, Mishra, P, Surolia, A, Varshney, U, Vijayan, M.
Deposit date:2014-10-25
Release date:2015-07-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Structural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implications.
Acta Crystallogr.,Sect.D, 71, 2015
4WRW
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BU of 4wrw by Molmil
Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase, Form IV
Descriptor: CHLORIDE ION, GLYCEROL, Uracil-DNA glycosylase
Authors:Arif, S.M, Geethanandan, K, Mishra, P, Surolia, A, Varshney, U, Vijayan, M.
Deposit date:2014-10-25
Release date:2015-07-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implications.
Acta Crystallogr.,Sect.D, 71, 2015
4WS1
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BU of 4ws1 by Molmil
Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with 5-fluorouracil (AB), Form II
Descriptor: 1,2-ETHANEDIOL, 5-FLUOROURACIL, CHLORIDE ION, ...
Authors:Arif, S.M, Geethanandan, K, Mishra, P, Surolia, A, Varshney, U, Vijayan, M.
Deposit date:2014-10-25
Release date:2015-07-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implications.
Acta Crystallogr.,Sect.D, 71, 2015
4WS5
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BU of 4ws5 by Molmil
Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with 5-nitrouracil, Form III
Descriptor: 5-nitrouracil, CHLORIDE ION, Uracil-DNA glycosylase
Authors:Arif, S.M, Geethanandan, K, Mishra, P, Surolia, A, Varshney, U, Vijayan, M.
Deposit date:2014-10-25
Release date:2015-07-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implications.
Acta Crystallogr.,Sect.D, 71, 2015
8DFM
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BU of 8dfm by Molmil
Ectodomain of full-length wild-type KIT-SCF dimers
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ...
Authors:Krimmer, S.G, Bertoletti, N, Mi, W, Schlessinger, J.
Deposit date:2022-06-22
Release date:2023-03-29
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DFQ
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BU of 8dfq by Molmil
Ectodomain of full-length KIT(T417I,delta418-419)-SCF dimers
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ...
Authors:Krimmer, S.G, Bertoletti, N, Mi, W, Schlessinger, J.
Deposit date:2022-06-22
Release date:2023-03-29
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (3.96 Å)
Cite:Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DFP
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BU of 8dfp by Molmil
Ectodomain of full-length KIT(DupA502,Y503)-SCF dimers
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ...
Authors:Bertoletti, N, Krimmer, S.G, Mi, W, Schlessinger, J.
Deposit date:2022-06-22
Release date:2023-03-29
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention.
Proc.Natl.Acad.Sci.USA, 120, 2023
4WPK
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BU of 4wpk by Molmil
Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase, Form I
Descriptor: CITRIC ACID, SODIUM ION, Uracil-DNA glycosylase
Authors:Arif, S.M, Geethanandan, K, Mishra, P, Surolia, A, Varshney, U, Vijayan, M.
Deposit date:2014-10-20
Release date:2015-07-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Structural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implications.
Acta Crystallogr.,Sect.D, 71, 2015
4X8K
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BU of 4x8k by Molmil
Mycobacterium tuberculosis RbpA-SID in complex with SigmaA domain 2
Descriptor: 1,2-ETHANEDIOL, RNA polymerase sigma factor SigA, RNA polymerase-binding protein RbpA, ...
Authors:Hubin, E.A, Flack, J.E, Tabib-Salazar, A, Paget, M.S, Darst, S.A, Campbell, E.A.
Deposit date:2014-12-10
Release date:2015-06-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.202 Å)
Cite:Structural, functional, and genetic analyses of the actinobacterial transcription factor RbpA.
Proc.Natl.Acad.Sci.USA, 112, 2015
4E2J
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BU of 4e2j by Molmil
X-Ray Crystal Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with mometasone furoate and TIF-2 coactivator fragment
Descriptor: Ancestral Glucocorticoid Receptor 2, FORMIC ACID, GLYCEROL, ...
Authors:Kohn, J.A, Deshpande, K, Ortlund, E.A.
Deposit date:2012-03-08
Release date:2012-03-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Deciphering Modern Glucocorticoid Cross-pharmacology Using Ancestral Corticosteroid Receptors.
J.Biol.Chem., 287, 2012
4EGJ
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BU of 4egj by Molmil
Crystal structure of D-alanine-D-alanine ligase from Burkholderia xenovorans
Descriptor: D-alanine--D-alanine ligase
Authors:SSGCID, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-03-31
Release date:2012-07-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Combining functional and structural genomics to sample the essential Burkholderia structome.
Plos One, 8, 2013
6DHA
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BU of 6dha by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Hydroxy Pioglitazone (M-IV)
Descriptor: Hydroxy Pioglitazone (M-IV), Peroxisome proliferator-activated receptor gamma, nonanoic acid
Authors:Shang, J, Mosure, S.A, Kojetin, D.J.
Deposit date:2018-05-18
Release date:2019-03-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structural Basis of Altered Potency and Efficacy Displayed by a Major in Vivo Metabolite of the Antidiabetic PPAR gamma Drug Pioglitazone.
J. Med. Chem., 62, 2019
5EJN
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BU of 5ejn by Molmil
Crystal structure of Juno, the mammalian egg receptor for sperm Izumo1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Sperm-egg fusion protein Juno
Authors:Nishimura, K, Han, L, Jovine, L.
Deposit date:2015-11-02
Release date:2016-02-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.703 Å)
Cite:Divergent evolution of vitamin B9 binding underlies Juno-mediated adhesion of mammalian gametes.
Curr.Biol., 26, 2016
7MZZ
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BU of 7mzz by Molmil
AUGbeta - FAM150A - ALKL1 60-128
Descriptor: ALK and LTK ligand 1
Authors:Rossi, P, Sowaileh, M, Reshetnyak, A.V, Kalodimos, C.G.
Deposit date:2021-05-24
Release date:2021-11-24
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Mechanism for the activation of the anaplastic lymphoma kinase receptor.
Nature, 600, 2021
7MZW
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BU of 7mzw by Molmil
Anaplastic lymphoma kinase (ALK) extracellular ligand binding region 673-1025
Descriptor: ALK tyrosine kinase receptor
Authors:Rossi, P, Sowaileh, M, Reshetnyak, A.V, Kalodimos, C.G.
Deposit date:2021-05-24
Release date:2021-12-08
Last modified:2021-12-15
Method:SOLUTION NMR
Cite:Mechanism for the activation of the anaplastic lymphoma kinase receptor.
Nature, 600, 2021
8OOO
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BU of 8ooo by Molmil
Glutamine synthetase from Methanothermococcus thermolithotrophicus in complex with 2-oxoglutarate and MgATP at 2.15 A resolution
Descriptor: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Mueller, M.-C, Wagner, T.
Deposit date:2023-04-05
Release date:2024-01-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.149 Å)
Cite:Differences in regulation mechanisms of glutamine synthetases from methanogenic archaea unveiled by structural investigations.
Commun Biol, 7, 2024
8OOQ
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BU of 8ooq by Molmil
Glutamine synthetase from Methanothermococcus thermolithotrophicus in complex with 2-oxoglutarate and Mg at 2.91 A resolution
Descriptor: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Mueller, M.-C, Wagner, T.
Deposit date:2023-04-05
Release date:2024-01-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Differences in regulation mechanisms of glutamine synthetases from methanogenic archaea unveiled by structural investigations.
Commun Biol, 7, 2024
3MI8
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BU of 3mi8 by Molmil
The structure of TL1A-DCR3 COMPLEX
Descriptor: TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15, SECRETED FORM, Tumor necrosis factor receptor superfamily member 6B
Authors:Zhan, C, Patskovsky, Y, Yan, Q, Li, Z, Ramagopal, U.A, Nathenson, S.G, Almo, S.C.
Deposit date:2010-04-09
Release date:2011-02-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.951 Å)
Cite:Decoy Strategies: The Structure of TL1A:DcR3 Complex.
Structure, 19, 2011
7MZX
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BU of 7mzx by Molmil
AUGalpha - FAM150B - ALKL2 77-152
Descriptor: ALK and LTK ligand 2
Authors:Rossi, P, Sowaileh, M, Reshetnyak, A.V, Kalodimos, C.G.
Deposit date:2021-05-24
Release date:2021-11-24
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Mechanism for the activation of the anaplastic lymphoma kinase receptor.
Nature, 600, 2021
8IK3
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BU of 8ik3 by Molmil
Structure of Stimulator of interferon genes/ligand complex
Descriptor: Stimulator of interferon genes protein,Immune protein Tsi3, cGAMP
Authors:Lu, D.F, Shang, G.J.
Deposit date:2023-02-28
Release date:2023-05-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The mechanism of STING autoinhibition and activation.
Mol.Cell, 83, 2023

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