5EJN

Crystal structure of Juno, the mammalian egg receptor for sperm Izumo1

Summary for 5EJN

• Entry DOI: 10.2210/pdb5ejn/pdb
• Descriptor: Sperm-egg fusion protein Juno, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
• Functional Keywords: fertilization, sperm receptor, gamete adhesion, egg-sperm membrane fusion, cell adhesion
• Biological source: Mus musculus (House Mouse)
• Cellular location: Cell membrane ; Lipid-anchor, GPI-anchor : Q9EQF4
• Total number of polymer chains: 2
• Total formula weight: 50655.87

Authors

Nishimura, K.,Han, L.,Jovine, L. (deposition date: 2015-11-02, release date: 2016-02-24, Last modification date: 2024-01-10)

• Primary citation: Han, L.,Nishimura, K.,Sadat Al Hosseini, H.,Bianchi, E.,Wright, G.J.,Jovine, L.; Divergent evolution of vitamin B9 binding underlies Juno-mediated adhesion of mammalian gametes.; Curr.Biol., 26:R100-R101, 2016; PubMed: 26859261; DOI: 10.1016/j.cub.2015.12.034

Experimental method

X-RAY DIFFRACTION (2.703 Å)