Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with uracil, Form II

Summary for 4WRU

Related4WRV 4WRW 4WRX 4WRY 4WRZ 4WS0 4WS1 4WS2 4WS3 4WS4 4WS5 4WS6 4WS7 4WS8
DescriptorUracil-DNA glycosylase, URACIL, CHLORIDE ION, ... (5 entities in total)
Functional Keywordsdna-repair, excision repair, conformational selection, ligand-binding, hydrolase
Biological sourceMycobacterium tuberculosis
Cellular locationCytoplasm  P9WFQ9
Total number of polymer chains1
Total molecular weight26053.18
Arif, S.M.,Geethanandan, K.,Mishra, P.,Surolia, A.,Varshney, U.,Vijayan, M. (deposition date: 2014-10-25, release date: 2015-07-15, Last modification date: 2017-11-22)
Primary citation
Arif, S.M.,Geethanandan, K.,Mishra, P.,Surolia, A.,Varshney, U.,Vijayan, M.
Structural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implications.
Acta Crystallogr.,Sect.D, 71:1514-1527, 2015
PubMed: 26143923 (PDB entries with the same primary citation)
DOI: 10.1107/S1399004715009311
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.21750.5%0.6%4.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-09-16