4WS3

Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with 6-aminouracil, Form IV

Summary for 4WS3

• Entry DOI: 10.2210/pdb4ws3/pdb
• Related: 4WRU 4WRV 4WRW 4WRX 4WRY 4WRZ 4WS0 4WS1 4WS2 4WS4 4WS5 4WS6 4WS7 4WS8
• Descriptor: Uracil-DNA glycosylase, 6-aminopyrimidine-2,4(3H,5H)-dione, DIMETHYL SULFOXIDE, ... (5 entities in total)
• Functional Keywords: dna-repair, excision repair, conformational selection, ligand-binding, hydrolase
• Biological source: Mycobacterium tuberculosis
• Cellular location: Cytoplasm : P9WFQ9
• Total number of polymer chains: 1
• Total formula weight: 26054.23

Authors

Arif, S.M.,Geethanandan, K.,Mishra, P.,Surolia, A.,Varshney, U.,Vijayan, M. (deposition date: 2014-10-25, release date: 2015-07-15, Last modification date: 2023-09-27)

• Primary citation: Arif, S.M.,Geethanandan, K.,Mishra, P.,Surolia, A.,Varshney, U.,Vijayan, M.; Structural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implications.; Acta Crystallogr.,Sect.D, 71:1514-1527, 2015; PubMed: 26143923; DOI: 10.1107/S1399004715009311

Experimental method

X-RAY DIFFRACTION (1.4 Å)