PDB: 36840 resultsInfo pagesStatus searchChemie searchBIRD

---

1ZPC	Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with 2-[2-(3-Chloro-phenyl)-2-hydroxy-acetylamino]-N-[4-guanidino-1-(thiazole-2-carbonyl)-butyl]-3-methyl-butyramide Descriptor: 2-[2-(3-CHLORO-PHENYL)-2-HYDROXY-ACETYLAMINO]-N-[4-GUANIDINO-1-(THIAZOLE-2-CARBONYL)-BUTYL]-3-METHYL-BUTYRAMIDE, Coagulation factor XI, SULFATE ION Authors: Deng, H, Bannister, T.D, Jin, L, Nagafuji, P, Celatka, C.A, Lin, J, Lazarova, T.I, Rynkiewicz, M.J, Quinn, J, Bibbins, F, Pandey, P, Gorga, J, Babine, R.E, Meyers, H.V, Abdel-Meguid, S.S, Strickler, J.E. Deposit date: 2005-05-16 Release date: 2006-04-18 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Synthesis, SAR exploration, and X-ray crystal structures of factor XIa inhibitors containing an alpha-ketothiazole arginine Bioorg.Med.Chem.Lett., 16, 2006
2Z2W	Human Wee1 kinase complexed with inhibitor PF0335770 Descriptor: CHLORIDE ION, GLYCEROL, N-[4-(2-CHLOROPHENYL)-1,3-DIOXO-1,2,3,6-TETRAHYDROPYRROLO[3,4-C]CARBAZOL-9-YL]FORMAMIDE, ... Authors: Squire, C.J, Baker, E.N. Deposit date: 2007-05-29 Release date: 2008-05-06 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Synthesis and Structure-Activity Relationships of 9-Amino-4-(2-chlorophenyl)pyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones and Related Formamides as Inhibitors of the Wee1 and Chk1 Checkpoint Kinases To be Published
1YZG	Structure of Human ADP-ribosylation factor-like 8 Descriptor: ADP-ribosylation factor-like 8, GUANOSINE-5'-DIPHOSPHATE Authors: Choe, J, Atanassova, A, Arrowsmith, C, Edwards, A, Sundstrom, M, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) Deposit date: 2005-02-28 Release date: 2005-03-22 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of Human ADP-ribosylation factor-like 8 To be Published, 2005
2EE2	Solution structures of the fn3 domain of human contactin 1 Descriptor: Contactin-1 Authors: Sato, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2007-02-15 Release date: 2007-08-21 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structures of the fn3 domain of human contactin 1 To be Published
1YZQ	GppNHp-Bound Rab6 GTPase Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, small GTP binding protein RAB6 isoform Authors: Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. Deposit date: 2005-02-28 Release date: 2005-07-26 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Structural basis of family-wide Rab GTPase recognition by rabenosyn-5. Nature, 436, 2005
3ITZ	Crystal Structure of p38a Mitogen-Activated Protein Kinase in Complex with a Pyrazolopyridazine Inhibitor Descriptor: 4-chloro-N-cyclopropyl-3-{[1-(2,6-difluorophenyl)-1H-pyrazolo[3,4-d]pyridazin-4-yl]amino}benzamide, Mitogen-activated protein kinase 14 Authors: Mohr, C, Jordan, S. Deposit date: 2009-08-28 Release date: 2010-03-02 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Part 2: Structure-activity relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38alpha mitogen-activated protein kinase. Bioorg.Med.Chem.Lett., 20, 2010
1V6D	The crystal structure of the trypsin complex with synthetic heterochiral peptide Descriptor: ACETATE ION, CALCIUM ION, METHYLAMINE, ... Authors: Shamaladevi, N, Pattabhi, V. Deposit date: 2003-11-28 Release date: 2004-12-07 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Secondary binding site of trypsin: revealed by crystal structure of trypsin-peptide complex. J.Biomol.Struct.Dyn., 22, 2005
1V2M	Benzamidine in complex with bovine trypsin variant X(triple.Glu)bT.A1 Descriptor: BENZAMIDINE, SULFATE ION, Trypsin Authors: Rauh, D, Klebe, G, Stubbs, M.T. Deposit date: 2003-10-17 Release date: 2004-06-01 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Understanding protein-ligand interactions: the price of protein flexibility J.Mol.Biol., 335, 2004
1Z06	GppNHp-Bound Rab33 GTPase Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-33B Authors: Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. Deposit date: 2005-03-01 Release date: 2005-07-26 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.81 Å) Cite: Structural basis of family-wide Rab GTPase recognition by rabenosyn-5. Nature, 436, 2005
1V2U	Benzamidine in complex with bovine trypsin varinat X(SSAI)bT.D1 Descriptor: BENZAMIDINE, CALCIUM ION, SULFATE ION, ... Authors: Rauh, D, Klebe, G, Stubbs, M.T. Deposit date: 2003-10-17 Release date: 2004-06-01 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Understanding protein-ligand interactions: the price of protein flexibility J.Mol.Biol., 335, 2004
1Z0D	GDP-Bound Rab5c GTPase Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... Authors: Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. Deposit date: 2005-03-01 Release date: 2005-07-26 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural basis of family-wide Rab GTPase recognition by rabenosyn-5. Nature, 436, 2005
2ZDU	Crystal Structure of human JNK3 complexed with an isoquinolone inhibitor Descriptor: 4-[(4-{[6-bromo-3-(methoxycarbonyl)-1-oxo-4-phenylisoquinolin-2(1H)-yl]methyl}phenyl)amino]-4-oxobutanoic acid, Mitogen-activated protein kinase 10 Authors: Sogabe, S, Ohra, T, Itoh, F, Habuka, N, Fujishima, A. Deposit date: 2007-11-27 Release date: 2008-09-23 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (1) Bioorg.Med.Chem., 16, 2008
1Z3K	Structural Insight into the Binding Diversity between the Tyr-Phosphorylated Human EphrinBs and Nck2 SH2 Domain Descriptor: Cytoplasmic protein NCK2 Authors: Ran, X, Song, J. Deposit date: 2005-03-14 Release date: 2005-03-29 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Structural insight into the binding diversity between the Tyr-phosphorylated human ephrinBs and Nck2 SH2 domain. J.Biol.Chem., 280, 2005
3V6R	Discovery of potent and selective covalent inhibitors of JNK Descriptor: 4-{[4-(dimethylamino)butanoyl]amino}-N-(3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide, Mitogen-activated protein kinase 10 Authors: Park, H, LoGrasso, P.V, Laughlin, J.D. Deposit date: 2011-12-20 Release date: 2012-02-01 Last modified: 2012-07-25 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Discovery of potent and selective covalent inhibitors of JNK. Chem.Biol., 19, 2012
2EL4	Solution structure of the 15th zf-C2H2 domain from human Zinc finger protein 268 Descriptor: ZINC ION, Zinc finger protein 268 Authors: Kurosaki, C, Nagashima, T, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2007-03-26 Release date: 2007-10-02 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Solution structure of the 15th zf-C2H2 domain from human Zinc finger protein 268 To be Published
2ELQ	Solution structure of the 14th C2H2 zinc finger of human Zinc finger protein 406 Descriptor: ZINC ION, Zinc finger protein 406 Authors: Tochio, N, Yoneyama, M, Koshiba, S, Watanabe, S, Harada, T, Umehara, T, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2007-03-27 Release date: 2008-04-01 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of the 14th C2H2 zinc finger of human Zinc finger protein 406 To be Published
2ELY	Solution structure of the third zf-C2H2 domain from human Zinc finger protein 224 Descriptor: ZINC ION, Zinc finger protein 224 Authors: Kurosaki, C, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2007-03-28 Release date: 2007-10-02 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of the third zf-C2H2 domain from human Zinc finger protein 224 To be Published
3V04	Discovery of Novel Allosteric MEK Inhibitors Possessing Classical and Non-classical Bidentate Ser212 Interactions. Descriptor: 4-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)-1H-indazole-5-carboxamide, ADENOSINE-5'-TRIPHOSPHATE, Dual specificity mitogen-activated protein kinase kinase 1, ... Authors: Heald, R, Jackson, P, Savy, P, Jones, M, Gancia, E, Burton, B, Newman, R, Boggs, J, Chan, E, Chan, J, Choo, E, Merchant, M, Ultsch, M, Wiesmann, C, Belvin, M, Price, S. Deposit date: 2011-12-07 Release date: 2012-05-09 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Discovery of Novel Allosteric Mitogen-Activated Protein Kinase Kinase (MEK) 1,2 Inhibitors Possessing Bidentate Ser212 Interactions. J.Med.Chem., 55, 2012
2EMI	Solution structure of the C2H2 type zinc finger (region 547-579) of human Zinc finger protein 484 Descriptor: ZINC ION, Zinc finger protein 484 Authors: Tomizawa, T, Tochio, N, Abe, H, Saito, K, Li, H, Sato, M, Koshiba, S, Kobayashi, N, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2007-03-28 Release date: 2007-10-02 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of the C2H2 type zinc finger (region 547-579) of human Zinc finger protein 484 To be Published
2EN2	Solution structure of the C2H2 type zinc finger (region 598-626) of human B-cell lymphoma 6 protein Descriptor: B-cell lymphoma 6 protein, ZINC ION Authors: Tochio, N, Tomizawa, T, Abe, H, Saito, K, Li, H, Sato, M, Koshiba, S, Kobayashi, N, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2007-03-28 Release date: 2007-10-02 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of the C2H2 type zinc finger (region 598-626) of human B-cell lymphoma 6 protein To be Published
3V6S	Discovery of potent and selective covalent inhibitors of JNK Descriptor: 3-{[4-(dimethylamino)butanoyl]amino}-N-(4-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide, Mitogen-activated protein kinase 10 Authors: Park, H, Laughlin, J.D, LoGrasso, P.V. Deposit date: 2011-12-20 Release date: 2012-02-01 Last modified: 2012-07-25 Method: X-RAY DIFFRACTION (2.97 Å) Cite: Discovery of potent and selective covalent inhibitors of JNK. Chem.Biol., 19, 2012
2E0Q	Crystal structure of K53E thioredoxin from Sulfolobus tokodaii strain7 Descriptor: thioredoxin Authors: Ming, H, Tanokura, M. Deposit date: 2006-10-11 Release date: 2007-10-02 Last modified: 2021-11-10 Method: X-RAY DIFFRACTION (1.49 Å) Cite: Crystal structure of thioredoxin domain of ST2123 from thermophilic archaea Sulfolobus tokodaii strain7 Proteins, 69, 2007
2E1X	NMR structure of the HIV-2 nucleocapsid protein Descriptor: Gag-Pol polyprotein (Pr160Gag-Pol), ZINC ION Authors: Matsui, T, Kodera, Y, Miyauchi, E, Tanaka, H, Endoh, H, Komatsu, H, Tanaka, T, Kohno, T, Maeda, T. Deposit date: 2006-11-03 Release date: 2007-06-05 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Structural role of the secondary active domain of HIV-2 NCp8 in multi-functionality Biochem.Biophys.Res.Commun., 358, 2007
1Z6Y	Structure Of Human ADP-Ribosylation Factor-Like 5 Descriptor: ADP-ribosylation factor-like protein 5, GUANOSINE-5'-DIPHOSPHATE Authors: Choe, J, Atanassova, A, Arrowsmith, C, Edwards, A, Sundstrom, M, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) Deposit date: 2005-03-23 Release date: 2005-04-05 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure Of Human ADP-Ribosylation Factor-Like 5 To be Published
2EMJ	Solution structure of the C2H2 type zinc finger (region 612-644) of human Zinc finger protein 28 homolog Descriptor: ZINC ION, Zinc finger protein 28 homolog Authors: Tomizawa, T, Tochio, N, Abe, H, Saito, K, Li, H, Sato, M, Koshiba, S, Kobayashi, N, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2007-03-28 Release date: 2007-10-02 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of the C2H2 type zinc finger (region 612-644) of human Zinc finger protein 28 homolog To be Published

<518519520521522523524525526527528529530531532533>