PDB: 72372 resultsInfo pagesStatus searchChemie searchBIRD

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6S0M	Structural and dynamic studies provide insights into specificity and allosteric regulation of Ribonuclease AS, a key enzyme in mycobacterial virulence Descriptor: 3'-5' exoribonuclease, MAGNESIUM ION, RNA (5'-R(P*G)-3') Authors: Berisio, R, Romano, M. Deposit date: 2019-06-17 Release date: 2019-08-28 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural and dynamic studies provide insights into specificity and allosteric regulation of ribonuclease as, a key enzyme in mycobacterial virulence. J.Biomol.Struct.Dyn., 38, 2020
6LU8	Cryo-EM structure of a human pre-60S ribosomal subunit - state A Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. Deposit date: 2020-01-26 Release date: 2020-08-26 Method: ELECTRON MICROSCOPY (3.13 Å) Cite: Structural snapshots of human pre-60S ribosomal particles before and after nuclear export. Nat Commun, 11, 2020
7DFG	Structure of COVID-19 RNA-dependent RNA polymerase bound to favipiravir Descriptor: 6-fluoro-3-oxo-4-(5-O-phosphono-beta-D-ribofuranosyl)-3,4-dihydropyrazine-2-carboxamide, MAGNESIUM ION, Non-structural protein 7, ... Authors: Li, Z, Zhou, Z, Yu, X. Deposit date: 2020-11-08 Release date: 2021-11-17 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Structural basis for repurpose and design of nucleotide drugs for treating COVID-19 To Be Published
7DFH	Structure of COVID-19 RNA-dependent RNA polymerase bound to ribavirin Descriptor: MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ... Authors: Li, Z, Zhou, Z, Yu, X. Deposit date: 2020-11-08 Release date: 2021-11-17 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (2.97 Å) Cite: Structural basis for repurpose and design of nucleotide drugs for treating COVID-19 To Be Published
7DKH	Crystal structure of the Ctr9/Paf1/Cdc73/Rtf1 quaternary complex Descriptor: Cell division control protein 73, RNA polymerase II-associated protein 1, RNA polymerase-associated protein CTR9, ... Authors: Chen, F.L, Liu, B.B, Guo, L, Li, D.F, Zhou, H, Long, J.F. Deposit date: 2020-11-24 Release date: 2021-11-24 Last modified: 2022-01-05 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Crystal Structure of the Core Module of the Yeast Paf1 Complex. J.Mol.Biol., 434, 2021
7D1A	cryo-EM structure of a group II intron RNP complexed with its reverse transcriptase Descriptor: Group II intron-encoded protein LtrA, RNA (5'-R(P*CP*AP*CP*AP*UP*CP*CP*AP*UP*AP*AP*C)-3'), RNA (692-MER) Authors: Liu, N, Dong, X.L, Hu, C.X, Zeng, J.W, Wang, J.W, Wang, J, Wang, H.W, Belfort, M. Deposit date: 2020-09-14 Release date: 2020-10-21 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Exon and protein positioning in a pre-catalytic group II intron RNP primed for splicing. Nucleic Acids Res., 48, 2020
8INK	human nuclear pre-60S ribosomal particle - State D Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Zhang, Y, Gao, N. Deposit date: 2023-03-10 Release date: 2023-08-09 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
8IDY	human nuclear pre-60S ribosomal particle - State F Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Zhang, Y, Gao, N. Deposit date: 2023-02-14 Release date: 2023-08-09 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (3 Å) Cite: Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
8IE3	human nuclear pre-60S ribosomal particle - State E Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Zhang, Y, Gao, N. Deposit date: 2023-02-15 Release date: 2023-08-09 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
8IPD	human nuclear pre-60S ribosomal particle - State C Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Zhang, Y, Gao, N. Deposit date: 2023-03-14 Release date: 2023-08-09 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
8IDT	human nuclear pre-60S ribosomal particle - State G Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Zhang, Y, Gao, N. Deposit date: 2023-02-14 Release date: 2023-08-09 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
7NJC	Crystal structure of the Toxoplasma CPSF4 YTH-domain in complex with a 7 mer m6A-modified RNA Descriptor: 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, N-methyladenosine, RNA (5'-R(*(6MZ)P*CP*A)-3'), ... Authors: Swale, C, Bowler, M.W. Deposit date: 2021-02-16 Release date: 2021-07-21 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.38 Å) Cite: A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental gene partitioning in Toxoplasma . Elife, 10, 2021
6XKB	Crystal structure of SR-related and CTD-associated factor 4(SCAF4-CID)with peptide S2,S5p-CTD Descriptor: S2,S5p-CTD peptide, SR-related and CTD-associated factor 4, UNKNOWN ATOM OR ION Authors: Zhou, M.Q, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2020-06-26 Release date: 2021-01-20 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural basis for the recognition of the S2, S5-phosphorylated RNA polymerase II CTD by the mRNA anti-terminator protein hSCAF4. Febs Lett., 596, 2022
3LP0	HIV-1 reverse transcriptase with inhibitor Descriptor: 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, MANGANESE (II) ION, Reverse transcriptase/ribonuclease H, ... Authors: Yan, Y, Munshi, S.K, Prasad, G.S, Su, H.P. Deposit date: 2010-02-04 Release date: 2010-06-09 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.79 Å) Cite: Structural basis for the inhibition of RNase H activity of HIV-1 reverse transcriptase by RNase H active site-directed inhibitors. J.Virol., 84, 2010
6LQM	Cryo-EM structure of a pre-60S ribosomal subunit - state C Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. Deposit date: 2020-01-14 Release date: 2020-08-26 Method: ELECTRON MICROSCOPY (3.09 Å) Cite: Structural snapshots of human pre-60S ribosomal particles before and after nuclear export. Nat Commun, 11, 2020
7YOT	Cryo-EM structure of RNA polymerase in complex with P protein tetramer of Newcastle disease virus Descriptor: NDV P protein, RNA-directed RNA polymerase L Authors: Chen, Y, Jingyuan, C. Deposit date: 2022-08-02 Release date: 2023-02-15 Last modified: 2023-08-30 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structure of the Newcastle Disease Virus L protein in complex with tetrameric phosphoprotein. Nat Commun, 14, 2023
7YOU	Cryo-EM structure of RNA polymerase in complex with P protein tetramer of Newcastle disease virus Descriptor: NDV P protein, RNA-directed RNA polymerase L Authors: Chen, Y, Jingyuan, C, Xiaoying, F. Deposit date: 2022-08-02 Release date: 2023-02-15 Last modified: 2023-08-30 Method: ELECTRON MICROSCOPY (3.41 Å) Cite: Structure of the Newcastle Disease Virus L protein in complex with tetrameric phosphoprotein. Nat Commun, 14, 2023
7YOV	Cryo-EM structure of RNA polymerase in complex with P protein tetramer of Newcastle disease virus Descriptor: NDV P protein, RNA-directed RNA polymerase L Authors: Chen, Y, Jingyuan, C, Xiaoying, F. Deposit date: 2022-08-02 Release date: 2023-02-15 Last modified: 2023-08-30 Method: ELECTRON MICROSCOPY (3.25 Å) Cite: Structure of the Newcastle Disease Virus L protein in complex with tetrameric phosphoprotein. Nat Commun, 14, 2023
6RFG	Structure of the Vaccinia core protein E11 Descriptor: 15 kDa core protein Authors: Grimm, C, Fischer, U. Deposit date: 2019-04-15 Release date: 2019-12-11 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (1.897 Å) Cite: Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes. Cell, 179, 2019
6DZ9	Solution structure of Rbfox2 RRM mimetic peptide CPfox2 Descriptor: CPfox2 Authors: Sun, Y.-T, Shortridge, M.D, Varani, G. Deposit date: 2018-07-03 Release date: 2019-05-15 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: A Small Cyclic beta-Hairpin Peptide Mimics the Rbfox2 RNA Recognition Motif and Binds to the Precursor miRNA 20b. Chembiochem, 20, 2019
6DZB	Solution structure of Rbfox2 RRM mimetic peptide CPfox5 Descriptor: CPfox5 Authors: Sun, Y.-T, Varani, G. Deposit date: 2018-07-03 Release date: 2019-05-15 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: A Small Cyclic beta-Hairpin Peptide Mimics the Rbfox2 RNA Recognition Motif and Binds to the Precursor miRNA 20b. Chembiochem, 20, 2019
3D5G	Structure of ribonuclease Sa2 complexes with mononucleotides: new aspects of catalytic reaction and substrate recognition Descriptor: Ribonuclease, SULFATE ION Authors: Bauerova-Hlinkova, V, Dvorsky, R, Povazanec, F, Sevcik, J. Deposit date: 2008-05-16 Release date: 2009-05-26 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structure of RNase Sa2 complexes with mononucleotides - new aspects of catalytic reaction and substrate recognition Febs J., 276, 2009
3DGY	Crystal structure of ribonuclease Sa2 with guanosine-2'-cyclophosphate Descriptor: GUANOSINE-2'-MONOPHOSPHATE, Ribonuclease, SULFATE ION, ... Authors: Sevcik, J, Bauerova-Hlinkova, V. Deposit date: 2008-06-16 Release date: 2009-06-16 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structure of RNase Sa2 complexes with mononucleotides - new aspects of catalytic reaction and substrate recognition Febs J., 276, 2009
3DH2	Crystal structure of ribonuclease Sa2 with guanosine-3'-cyclophosphate prepared by cocrystallization Descriptor: GUANOSINE-3'-MONOPHOSPHATE, Ribonuclease, SULFATE ION, ... Authors: Sevcik, J, Bauerova-Hlinkova, V. Deposit date: 2008-06-16 Release date: 2009-06-16 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structure of RNase Sa2 complexes with mononucleotides - new aspects of catalytic reaction and substrate recognition Febs J., 276, 2009
7NHN	VgaL, an antibiotic resistance ABCF, in complex with 70S ribosome from Listeria monocytogenes Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Crowe-McAuliffe, C, Turnbull, K.J, Hauryliuk, V, Wilson, D.N. Deposit date: 2021-02-10 Release date: 2021-05-05 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens. Nat Commun, 12, 2021

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