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8COB
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BU of 8cob by Molmil
Crystal structure of human PCNA in complex with ERCC6L2 PIP box peptide
Descriptor: DNA excision repair protein ERCC-6-like 2, Proliferating cell nuclear antigen
Authors:Ariza, A.
Deposit date:2023-02-27
Release date:2023-04-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:ERCC6L2 mitigates replication stress and promotes centromere stability.
Cell Rep, 42, 2023
5K97
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BU of 5k97 by Molmil
Flap endonuclease 1 (FEN1) D233N with cleaved product fragment and Sm3+
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*CP*CP*GP*TP*CP*C)-3'), DNA (5'-D(*AP*CP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*T)-3'), ...
Authors:Tsutakawa, S.E, Arvai, A.S, Tainer, J.A.
Deposit date:2016-05-31
Release date:2017-06-28
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.102 Å)
Cite:Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability.
Nat Commun, 8, 2017
5ZU1
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BU of 5zu1 by Molmil
Crystal Structure of BZ junction in diverse sequence
Descriptor: DNA (5'-D(*AP*CP*GP*GP*TP*TP*TP*AP*AP*GP*GP*CP*GP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*TP*CP*GP*CP*GP*CP*GP*CP*CP*TP*TP*AP*AP*AP*CP*C)-3'), Double-stranded RNA-specific adenosine deaminase
Authors:Kim, K.K, Kim, D.
Deposit date:2018-05-05
Release date:2018-08-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.009 Å)
Cite:Sequence preference and structural heterogeneity of BZ junctions.
Nucleic Acids Res., 46, 2018
3BBB
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BU of 3bbb by Molmil
Crystal structure of the NM23-H2 transcription factor complex with dinucleotide d(AG)
Descriptor: DNA (5'-D(*AP*G)-3'), Nucleoside diphosphate kinase B
Authors:Weichsel, A, Montfort, W.R.
Deposit date:2007-11-09
Release date:2008-09-23
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:NM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression but does not cleave the nuclease hypersensitive element III1.
Mol.Cancer Ther., 8, 2009
8GAO
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BU of 8gao by Molmil
bacteriophage T4 stalled primosome with mutant gp41-E227Q
Descriptor: DNA (70-mer), DNA primase, DnaB-like replicative helicase, ...
Authors:Feng, X, Li, H.
Deposit date:2023-02-23
Release date:2023-06-07
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
Nat Commun, 14, 2023
5JKR
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BU of 5jkr by Molmil
vaccinia virus D4/A20(1-50)w43a mutant
Descriptor: DNA polymerase processivity factor component A20, SULFATE ION, Uracil-DNA glycosylase
Authors:Contesto-Richefeu, C, Tarbouriech, N, Brazzolotto, X, Burmeister, W.P, Peyrefitte, C.N, Iseni, F.
Deposit date:2016-04-26
Release date:2016-09-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural analysis of point mutations at the Vaccinia virus A20/D4 interface.
Acta Crystallogr.,Sect.F, 72, 2016
2ZUC
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BU of 2zuc by Molmil
Crystal structure of left-handed RadA filament
Descriptor: DNA repair and recombination protein radA
Authors:Chang, Y.W, Ko, T.P, Wang, T.F, Wang, A.H.J.
Deposit date:2008-10-15
Release date:2009-04-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Three new structures of left-handed RADA helical filaments: structural flexibility of N-terminal domain is critical for recombinase activity
Plos One, 4, 2009
6VOY
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BU of 6voy by Molmil
Cryo-EM structure of HTLV-1 instasome
Descriptor: DNA (25-MER), DNA (5'-D(P*AP*CP*AP*CP*AP*CP*TP*TP*GP*AP*CP*TP*AP*GP*GP*GP*TP*G)-3'), DNA-binding protein 7d, ...
Authors:Bhatt, V, Shi, K, Sundborger, A, Aihara, H.
Deposit date:2020-02-01
Release date:2020-07-01
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of host protein hijacking in human T-cell leukemia virus integration.
Nat Commun, 11, 2020
6VYP
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BU of 6vyp by Molmil
Crystal structure of the LSD1/CoREST histone demethylase bound to its nucleosome substrate
Descriptor: DNA (191-MER), FLAVIN-ADENINE DINUCLEOTIDE, Histone H2A type 1, ...
Authors:Kim, S, Zhu, J, Eek, P, Yennawar, N, Song, T.
Deposit date:2020-02-27
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.99 Å)
Cite:Crystal Structure of the LSD1/CoREST Histone Demethylase Bound to Its Nucleosome Substrate.
Mol.Cell, 78, 2020
6M05
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BU of 6m05 by Molmil
Trimolecular G-quadruplex
Descriptor: DNA (5'-D(*GP*TP*TP*AP*GP*G)-3')
Authors:Jing, H.T, Fu, W.Q, Zhang, N.
Deposit date:2020-02-20
Release date:2021-01-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR structural study on the self-trimerization of d(GTTAGG) into a dynamic trimolecular G-quadruplex assembly preferentially in Na+ solution with a moderate K+ tolerance.
Nucleic Acids Res., 49, 2021
2C41
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BU of 2c41 by Molmil
X-ray structure of Dps from Thermosynechococcus elongatus
Descriptor: CHLORIDE ION, DPS FAMILY DNA-BINDING STRESS RESPONSE PROTEIN, TETRAETHYLENE GLYCOL, ...
Authors:Ilari, A, Franceschini, S, Ceci, P, Chiancone, E.
Deposit date:2005-10-14
Release date:2006-10-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Antioxidant Dps Protein from the Thermophilic Cyanobacterium Thermosynechococcus Elongatus.
FEBS J., 273, 2006
5JKS
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BU of 5jks by Molmil
vaccinia virus D4 R167A mutant /A20(1-50)
Descriptor: DNA polymerase processivity factor component A20, SULFATE ION, Uracil-DNA glycosylase
Authors:Contesto-Richefeu, C, Tarbouriech, N, Brazzolotto, X, Burmeister, W.P, Peyrefitte, C.N, Iseni, F.
Deposit date:2016-04-26
Release date:2016-09-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structural analysis of point mutations at the Vaccinia virus A20/D4 interface.
Acta Crystallogr.,Sect.F, 72, 2016
7SX5
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BU of 7sx5 by Molmil
Crystal structure of ligase I with nick duplexes containing mismatch A:C
Descriptor: ADENOSINE MONOPHOSPHATE, DNA chain 1, DNA chain 2, ...
Authors:Tang, Q, Gulkis, M, McKenna, R, Caglayan, M.
Deposit date:2021-11-22
Release date:2022-07-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of LIG1 that engage with mutagenic mismatches inserted by pol beta in base excision repair.
Nat Commun, 13, 2022
7SXE
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BU of 7sxe by Molmil
Crystal structure of ligase I with nick duplexes containing cognate G:T
Descriptor: ADENOSINE MONOPHOSPHATE, DNA chain 1, DNA chain 2, ...
Authors:Tang, Q, Gulkis, M, McKenna, R, Caglayan, M.
Deposit date:2021-11-22
Release date:2022-07-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of LIG1 that engage with mutagenic mismatches inserted by pol beta in base excision repair.
Nat Commun, 13, 2022
7SUM
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BU of 7sum by Molmil
Crystal structure of human ligase I with nick duplexes containing cognate A:T
Descriptor: ADENOSINE MONOPHOSPHATE, DNA ligase 1, DNA(5'-*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*A-3'), ...
Authors:Tang, Q, Gulkis, M, McKenna, R, Caglayan, M.
Deposit date:2021-11-17
Release date:2022-07-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of LIG1 that engage with mutagenic mismatches inserted by pol beta in base excision repair.
Nat Commun, 13, 2022
5VU5
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BU of 5vu5 by Molmil
TNA polymerase, apo
Descriptor: DNA polymerase
Authors:Chim, N, Chaput, J.C.
Deposit date:2017-05-18
Release date:2017-12-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for TNA synthesis by an engineered TNA polymerase.
Nat Commun, 8, 2017
2ZUB
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BU of 2zub by Molmil
Left handed RadA
Descriptor: DNA repair and recombination protein radA
Authors:Chang, Y.W, Ko, T.P, Wang, T.F, Wang, A.H.J.
Deposit date:2008-10-15
Release date:2009-04-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Three new structures of left-handed RADA helical filaments: structural flexibility of N-terminal domain is critical for recombinase activity
Plos One, 4, 2009
2ZUD
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BU of 2zud by Molmil
Crystal Structure of Left-handed RadA Filament
Descriptor: DNA repair and recombination protein radA
Authors:Chang, Y.W, Ko, T.P, Wang, T.F, Wang, A.H.J.
Deposit date:2008-10-16
Release date:2009-04-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Three new structures of left-handed RADA helical filaments: structural flexibility of N-terminal domain is critical for recombinase activity
Plos One, 4, 2009
8EMH
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BU of 8emh by Molmil
CryoEM characterization of a unique AAA+ BrxL phage restriction factor
Descriptor: DNA (63-MER), DNA (64-MER), Protease Lon-related BREX system protein BrxL
Authors:Shen, B.W, Stoddard, B.L.
Deposit date:2022-09-27
Release date:2023-02-01
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:Structure, substrate binding and activity of a unique AAA+ protein: the BrxL phage restriction factor.
Nucleic Acids Res., 51, 2023
4ZQ9
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BU of 4zq9 by Molmil
X-ray structure of AAV-2 OBD bound to AAVS1 site 3:1
Descriptor: DNA (5'-D(*CP*GP*CP*CP*CP*AP*GP*CP*GP*AP*GP*CP*GP*AP*GP*CP*GP*AP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*CP*TP*CP*GP*CP*TP*CP*GP*CP*TP*CP*GP*CP*TP*GP*GP*GP*C)-3'), MANGANESE (II) ION, ...
Authors:Musayev, F.N, Zarate-Perez, F, Escalante, C.R.
Deposit date:2015-05-08
Release date:2015-09-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Insights into the Assembly of the Adeno-associated Virus Type 2 Rep68 Protein on the Integration Site AAVS1.
J.Biol.Chem., 290, 2015
1Y1V
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BU of 1y1v by Molmil
Refined RNA Polymerase II-TFIIS complex
Descriptor: DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 19 kDa polypeptide, ...
Authors:Kettenberger, H, Armache, K.-J, Cramer, P.
Deposit date:2004-11-19
Release date:2004-12-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS.
Mol.Cell, 16, 2004
4Q48
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BU of 4q48 by Molmil
Structure of the RecQ Catalytic Core from Deinococcus radiodurans
Descriptor: DNA helicase RecQ, ZINC ION
Authors:Chen, S.C, Yang, C.S, Chen, Y.
Deposit date:2014-04-14
Release date:2015-05-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.797 Å)
Cite:Crystal structure of Deinococcus radiodurans RecQ helicase catalytic core domain: the interdomain flexibility.
Biomed Res Int, 2014, 2014
1MSW
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BU of 1msw by Molmil
Structural basis for the transition from initiation to elongation transcription in T7 RNA polymerase
Descriptor: DNA-directed RNA polymerase, Non-Template DNA, RNA message, ...
Authors:Yin, Y.W, Steitz, T.A.
Deposit date:2002-09-19
Release date:2002-11-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for the Transition from Initiation to Elongation Transcription in T7 RNA Polymerase
Science, 298, 2002
4XO0
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BU of 4xo0 by Molmil
Crystal structure of 5'-CTTATPPTAZZATAAG in a host-guest complex
Descriptor: DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*T)-3'), DNA (5'-D(P*AP*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3'), reverse transcriptase
Authors:Georgiadis, M.M, Singh, I.
Deposit date:2015-01-16
Release date:2015-05-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for a six nucleotide genetic alphabet.
J. Am. Chem. Soc., 137, 2015
8K87
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BU of 8k87 by Molmil
Dimer structure of procaryotic Ago
Descriptor: DNA (41-mer), MAGNESIUM ION, Piwi domain protein, ...
Authors:Gao, X, Sun, D, Cui, S, Wang, Y.
Deposit date:2023-07-29
Release date:2024-07-03
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Nucleic acid-induced NADase activation of a short Sir2-associated prokaryotic Argonaute system.
Cell Rep, 43, 2024

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