7SX5
Crystal structure of ligase I with nick duplexes containing mismatch A:C
Summary for 7SX5
| Entry DOI | 10.2210/pdb7sx5/pdb |
| Related | 7SUM |
| Descriptor | DNA ligase 1, DNA chain 1, DNA chain 2, ... (6 entities in total) |
| Functional Keywords | protein-dna complex, ligase |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 85648.05 |
| Authors | Tang, Q.,Gulkis, M.,McKenna, R.,Caglayan, M. (deposition date: 2021-11-22, release date: 2022-07-13, Last modification date: 2023-10-18) |
| Primary citation | Tang, Q.,Gulkis, M.,McKenna, R.,Caglayan, M. Structures of LIG1 that engage with mutagenic mismatches inserted by pol beta in base excision repair. Nat Commun, 13:3860-3860, 2022 Cited by PubMed: 35790757DOI: 10.1038/s41467-022-31585-w PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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