4IJ2
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![BU of 4ij2 by Molmil](/molmil-images/mine/4ij2) | Human methemoglobin in complex with the second and third NEAT domains of IsdH from Staphylococcus aureus | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, Iron-regulated surface determinant protein H, ... | Authors: | Dickson, C.F, Jacques, D.A, Guss, J.M, Gell, D.A. | Deposit date: | 2012-12-21 | Release date: | 2013-12-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (4.24 Å) | Cite: | Structure of the Hemoglobin-IsdH Complex Reveals the Molecular Basis of Iron Capture by Staphylococcus aureus J.Biol.Chem., 289, 2014
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4MJ4
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![BU of 4mj4 by Molmil](/molmil-images/mine/4mj4) | Human iduronidase apo structure P21 form | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-L-iduronidase, CHLORIDE ION, ... | Authors: | Bie, H, Yin, J, He, X, Kermode, A.R, Goddard-Borger, E.D, Withers, S.G, James, M.N.G. | Deposit date: | 2013-09-03 | Release date: | 2013-09-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.172 Å) | Cite: | Insights into mucopolysaccharidosis I from the structure and action of alpha-L-iduronidase. Nat.Chem.Biol., 9, 2013
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4IL4
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![BU of 4il4 by Molmil](/molmil-images/mine/4il4) | The pentameric ligand-gated ion channel GLIC in complex with Se-DDM | Descriptor: | ACETATE ION, CHLORIDE ION, Proton-gated ion channel, ... | Authors: | Sauguet, L, Malherbe, L, Corringer, P.J, Delarue, M. | Deposit date: | 2012-12-29 | Release date: | 2013-02-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels. Embo J., 32, 2013
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4MJW
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![BU of 4mjw by Molmil](/molmil-images/mine/4mjw) | Crystal Structure of Choline Oxidase in Complex with the Reaction Product Glycine Betaine | Descriptor: | ACETATE ION, Choline oxidase, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Wang, Y.-F, Salvi, F, Gadda, G, Weber, I.T. | Deposit date: | 2013-09-04 | Release date: | 2014-02-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of choline oxidase in complex with the reaction product glycine betaine. Acta Crystallogr.,Sect.D, 70, 2014
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4IN7
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![BU of 4in7 by Molmil](/molmil-images/mine/4in7) | (M)L214N mutant of the Rhodobacter sphaeroides Reaction Center | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, ... | Authors: | Saer, R.G, Hardjasa, A, Murphy, M.E.P, Beatty, J.T. | Deposit date: | 2013-01-04 | Release date: | 2013-06-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Role of Rhodobacter sphaeroides photosynthetic reaction center residue M214 in the composition, absorbance properties, and conformations of H(A) and B(A) cofactors. Biochemistry, 52, 2013
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3JT9
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![BU of 3jt9 by Molmil](/molmil-images/mine/3jt9) | Structure of neuronal nitric oxide synthase heme domain in the ferrous state complexed with N~5~-[2-(ethylsulfanyl)ethanimidoyl]-L-ornithine | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, Nitric oxide synthase, ... | Authors: | Li, H, Poulos, T.L. | Deposit date: | 2009-09-11 | Release date: | 2010-01-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Heme-coordinating inhibitors of neuronal nitric oxide synthase. Iron-thioether coordination is stabilized by hydrophobic contacts without increased inhibitor potency. J.Am.Chem.Soc., 132, 2010
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3JTK
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![BU of 3jtk by Molmil](/molmil-images/mine/3jtk) | Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD90055 | Descriptor: | (2R)-3-benzyl-2-(2-bromo-4-hydroxy-5-methoxyphenyl)-1,3-thiazolidin-4-one, Glycylpeptide N-tetradecanoyltransferase 1, TETRADECANOYL-COA | Authors: | Qiu, W, Hutchinson, A, Wernimont, A, Lin, Y.-H, Kania, A, Ravichandran, M, Kozieradzki, I, Cossar, D, Schapira, M, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Wyatt, P.G, Ferguson, M.A.J, Frearson, J.A, Brand, S.Y, Robinson, D.A, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC) | Deposit date: | 2009-09-12 | Release date: | 2009-09-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD90055 To be Published
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4IEH
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![BU of 4ieh by Molmil](/molmil-images/mine/4ieh) | |
3JUU
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![BU of 3juu by Molmil](/molmil-images/mine/3juu) | Crystal structure of porphyranase B (PorB) from Zobellia galactanivorans | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, SULFATE ION, ... | Authors: | Hehemann, J.H, Correc, G, Barbeyron, T, Michel, G, Czjzek, M. | Deposit date: | 2009-09-15 | Release date: | 2010-04-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Transfer of carbohydrate-active enzymes from marine bacteria to Japanese gut microbiota. Nature, 464, 2010
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4IFV
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![BU of 4ifv by Molmil](/molmil-images/mine/4ifv) | Detecting Allosteric Sites of HIV-1 Reverse Transcriptase by X-Ray Crystallographic Fragment Screening | Descriptor: | 4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile, DIMETHYL SULFOXIDE, Exoribonuclease H, ... | Authors: | Bauman, J.D, Patel, D, Fromer, M, Arnold, E. | Deposit date: | 2012-12-15 | Release date: | 2013-02-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Detecting Allosteric Sites of HIV-1 Reverse Transcriptase by X-ray Crystallographic Fragment Screening. J.Med.Chem., 56, 2013
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4MQX
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![BU of 4mqx by Molmil](/molmil-images/mine/4mqx) | CLC-ec1 Fab Complex Cysless A399C-A432C mutant | Descriptor: | CHLORIDE ION, ERIC, H(+)/Cl(-) exchange transporter ClcA, ... | Authors: | Basilio, D, Noack, K, Picollo, A, Accardi, A. | Deposit date: | 2013-09-16 | Release date: | 2014-04-16 | Last modified: | 2014-05-28 | Method: | X-RAY DIFFRACTION (3.516 Å) | Cite: | Conformational changes required for H(+)/Cl(-) exchange mediated by a CLC transporter. Nat.Struct.Mol.Biol., 21, 2014
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4N7K
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![BU of 4n7k by Molmil](/molmil-images/mine/4n7k) | Zinc Substituted Reaction Center of the Rhodobacter sphaeroides | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CARDIOLIPIN, FE (III) ION, ... | Authors: | Hardjasa, A, Murphy, M.E.P. | Deposit date: | 2013-10-15 | Release date: | 2014-02-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural and kinetic properties of Rhodobacter sphaeroides photosynthetic reaction centers containing exclusively Zn-coordinated bacteriochlorophyll as bacteriochlorin cofactors. Biochim.Biophys.Acta, 1837, 2013
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4IL9
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![BU of 4il9 by Molmil](/molmil-images/mine/4il9) | The pentameric ligand-gated ion channel GLIC A237F in complex with bromide | Descriptor: | ACETATE ION, BROMIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | Authors: | Sauguet, L, Corringer, P.J, Delarue, M. | Deposit date: | 2012-12-29 | Release date: | 2013-02-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.83 Å) | Cite: | Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels. Embo J., 32, 2013
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4IMX
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![BU of 4imx by Molmil](/molmil-images/mine/4imx) | Structure of bovine endothelial nitric oxide synthase heme domain in complex with 3,5-bis(2-(6-amino-4-methylpyridin-2-yl)ethyl)benzonitrile | Descriptor: | 3,5-bis[2-(6-amino-4-methylpyridin-2-yl)ethyl]benzonitrile, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ... | Authors: | Li, H, Poulos, T.L. | Deposit date: | 2013-01-03 | Release date: | 2013-04-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure-guided design of selective inhibitors of neuronal nitric oxide synthase. J.Med.Chem., 56, 2013
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3K35
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![BU of 3k35 by Molmil](/molmil-images/mine/3k35) | Crystal Structure of Human SIRT6 | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, NAD-dependent deacetylase sirtuin-6, SULFATE ION, ... | Authors: | Pan, P.W, Dong, A, Qiu, W, Loppnau, P, Wang, J, Ravichandran, M, Bochkarev, A, Bountra, C, Weigelt, J, Arrowsmith, C.H, Min, J, Edwards, A.M, Structural Genomics Consortium (SGC) | Deposit date: | 2009-10-01 | Release date: | 2009-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and biochemical functions of SIRT6. J.Biol.Chem., 286, 2011
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4ILA
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![BU of 4ila by Molmil](/molmil-images/mine/4ila) | The pentameric ligand-gated ion channel GLIC A237F in complex with Cesium | Descriptor: | ACETATE ION, CESIUM ION, CHLORIDE ION, ... | Authors: | Sauguet, L, Corringer, P.J, Delarue, M. | Deposit date: | 2012-12-29 | Release date: | 2013-02-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels. Embo J., 32, 2013
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3K7T
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![BU of 3k7t by Molmil](/molmil-images/mine/3k7t) | Crystal structure of apo-form 6-hydroxy-L-nicotine oxidase, crystal form P3121 | Descriptor: | (1R)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(pentadecanoyloxy)methyl]ethyl (12E)-hexadeca-9,12-dienoate, 6-hydroxy-L-nicotine oxidase, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Bourenkov, G.P, Kachalova, G.S, Bartunik, H.D. | Deposit date: | 2009-10-13 | Release date: | 2010-01-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal Structure Analysis of Free and Substrate-Bound 6-Hydroxy-l-Nicotine Oxidase from Arthrobacter nicotinovorans. J.Mol.Biol., 396, 2010
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3K8T
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![BU of 3k8t by Molmil](/molmil-images/mine/3k8t) | Structure of eukaryotic rnr large subunit R1 complexed with designed adp analog compound | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 2'-deoxy-2'-(2-hydroxyethyl)adenosine 5'-(trihydrogen diphosphate), GLYCEROL, ... | Authors: | Sun, D, Xu, H, Dealwis, C, Lee, R.E. | Deposit date: | 2009-10-14 | Release date: | 2010-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-Based Design, Synthesis, and Evaluation of 2'-(2-Hydroxyethyl)-2'-deoxyadenosine and the 5'-Diphosphate Derivative as Ribonucleotide Reductase Inhibitors Chemmedchem, 4, 2009
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4IP2
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![BU of 4ip2 by Molmil](/molmil-images/mine/4ip2) | Putative Aromatic Acid Decarboxylase | Descriptor: | 1,2-ETHANEDIOL, Aromatic Acid Decarboxylase, GLYCEROL, ... | Authors: | Schneider, G, Brunner, K, Izumi, A, Jacewicz, A. | Deposit date: | 2013-01-09 | Release date: | 2013-07-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural insights into the UbiD protein family from the crystal structure of PA0254 from Pseudomonas aeruginosa. Plos One, 8, 2013
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3K9O
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![BU of 3k9o by Molmil](/molmil-images/mine/3k9o) | The crystal structure of E2-25K and UBB+1 complex | Descriptor: | Ubiquitin, Ubiquitin-conjugating enzyme E2 K | Authors: | Kang, G.B, Ko, S, Song, S.M, Lee, W, Eom, S.H. | Deposit date: | 2009-10-16 | Release date: | 2010-09-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Basis of E2-25K/UBB+1 Interaction for Neurotoxicity of Alzheimer Disease by Proteasome Inhibition To be Published
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3JBI
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![BU of 3jbi by Molmil](/molmil-images/mine/3jbi) | MDFF model of the vinculin tail domain bound to F-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Kim, L.Y, Thompson, P.M, Lee, H.T, Pershad, M, Campbell, S.L, Alushin, G.M. | Deposit date: | 2015-09-02 | Release date: | 2015-11-04 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (8.5 Å) | Cite: | The Structural Basis of Actin Organization by Vinculin and Metavinculin. J.Mol.Biol., 428, 2016
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3KAB
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![BU of 3kab by Molmil](/molmil-images/mine/3kab) | Structure-guided design of alpha-amino acid-derived Pin1 inhibitors | Descriptor: | 6-methyl-1H-indole-2-carboxylic acid, DODECAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | Authors: | Baker, L.M, Dokurno, P, Robinson, D.A, Surgenor, A.E, Murray, J.B, Potter, A.J, Moore, J.D. | Deposit date: | 2009-10-19 | Release date: | 2009-12-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Structure-guided design of alpha-amino acid-derived Pin1 inhibitors Bioorg.Med.Chem.Lett., 20, 2010
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4IMS
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![BU of 4ims by Molmil](/molmil-images/mine/4ims) | Structure of rat neuronal nitric oxide synthase heme domain in complex with 6,6'-((5-(3-aminopropyl)-1,3-phenylene)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine) | Descriptor: | 6,6'-{[5-(3-aminopropyl)benzene-1,3-diyl]diethane-2,1-diyl}bis(4-methylpyridin-2-amine), ACETATE ION, CHLORIDE ION, ... | Authors: | Li, H, Poulos, T.L. | Deposit date: | 2013-01-03 | Release date: | 2013-04-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure-guided design of selective inhibitors of neuronal nitric oxide synthase. J.Med.Chem., 56, 2013
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3J1Z
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![BU of 3j1z by Molmil](/molmil-images/mine/3j1z) | Inward-Facing Conformation of the Zinc Transporter YiiP revealed by Cryo-electron Microscopy | Descriptor: | Cation efflux family protein | Authors: | Coudray, N, Valvo, S, Hu, M, Lasala, R, Kim, C, Vink, M, Zhou, M, Provasi, D, Filizola, M, Tao, J, Fang, J, Penczek, P.A, Ubarretxena-Belandia, I, Stokes, D.L, Transcontinental EM Initiative for Membrane Protein Structure (TEMIMPS) | Deposit date: | 2012-07-24 | Release date: | 2012-10-10 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (13 Å) | Cite: | Inward-facing conformation of the zinc transporter YiiP revealed by cryoelectron microscopy. Proc.Natl.Acad.Sci.USA, 110, 2013
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3JCU
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![BU of 3jcu by Molmil](/molmil-images/mine/3jcu) | Cryo-EM structure of spinach PSII-LHCII supercomplex at 3.2 Angstrom resolution | Descriptor: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | Authors: | Wei, X.P, Zhang, X.Z, Su, X.D, Cao, P, Liu, X.Y, Li, M, Chang, W.R, Liu, Z.F. | Deposit date: | 2016-03-10 | Release date: | 2016-05-25 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of spinach photosystem II-LHCII supercomplex at 3.2 A resolution Nature, 534, 2016
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