3JTK
Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD90055
Summary for 3JTK
Entry DOI | 10.2210/pdb3jtk/pdb |
Related | 3IU1 3IU2 3IWE |
Descriptor | Glycylpeptide N-tetradecanoyltransferase 1, TETRADECANOYL-COA, (2R)-3-benzyl-2-(2-bromo-4-hydroxy-5-methoxyphenyl)-1,3-thiazolidin-4-one, ... (4 entities in total) |
Functional Keywords | transferase, n-myristoyltransferase, nmt1, acyltransferase, phosphoprotein, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P30419 |
Total number of polymer chains | 2 |
Total formula weight | 91432.73 |
Authors | Qiu, W.,Hutchinson, A.,Wernimont, A.,Lin, Y.-H.,Kania, A.,Ravichandran, M.,Kozieradzki, I.,Cossar, D.,Schapira, M.,Arrowsmith, C.H.,Bountra, C.,Weigelt, J.,Edwards, A.M.,Wyatt, P.G.,Ferguson, M.A.J.,Frearson, J.A.,Brand, S.Y.,Robinson, D.A.,Bochkarev, A.,Hui, R.,Structural Genomics Consortium (SGC) (deposition date: 2009-09-12, release date: 2009-09-22, Last modification date: 2023-09-06) |
Primary citation | Qiu, W.,Hutchinson, A.,Wernimont, A.,Lin, Y.-H.,Kania, A.,Ravichandran, M.,Kozieradzki, I.,Cossar, D.,Schapira, M.,Arrowsmith, C.H.,Bountra, C.,Weigelt, J.,Edwards, A.M.,Wyatt, P.G.,Ferguson, M.A.J.,Frearson, J.A.,Brand, S.Y.,Robinson, D.A.,Bochkarev, A.,Hui, R. Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD90055 To be Published, |
Experimental method | X-RAY DIFFRACTION (1.61 Å) |
Structure validation
Download full validation report