3JTK
Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD90055
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glycylpeptide N-tetradecanoyltransferase 1 | polymer | 383 | 44541.3 | 2 | UniProt (P30419) Pfam (PF01233) Pfam (PF02799) | Homo sapiens (human) | Peptide N-myristoyltransferase 1, Myristoyl-CoA:protein N-myristoyltransferase 1, NMT 1, Type I N-myristoyltransferase |
| 2 | C, E (A, B) | TETRADECANOYL-COA | non-polymer | 977.9 | 2 | Chemie (MYA) | |||
| 3 | D (A) | (2R)-3-benzyl-2-(2-bromo-4-hydroxy-5-methoxyphenyl)-1,3-thiazolidin-4-one | non-polymer | 394.3 | 1 | Chemie (X55) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 875 | Chemie (HOH) |
Sequence modifications
A, B: 115 - 496 (UniProt: P30419)
| PDB | External Database | Details |
|---|---|---|
| Gly 114 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 89082.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 2350.1 | |
| All* | Total formula weight | 91432.7 |
