3IWE
Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD85646
Summary for 3IWE
Entry DOI | 10.2210/pdb3iwe/pdb |
Related | 3IU1 3IU2 |
Descriptor | Glycylpeptide N-tetradecanoyltransferase 1, TETRADECANOYL-COA, 2,6-dichloro-4-(2-piperazin-1-ylpyridin-4-yl)-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide, ... (4 entities in total) |
Functional Keywords | transferase, n-myristoyltransferase, nmt, acyltransferase, phosphoprotein, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P30419 |
Total number of polymer chains | 2 |
Total formula weight | 92029.29 |
Authors | Qiu, W.,Hutchinson, A.,Wernimont, A.,Lin, Y.-H.,Kania, A.,Ravichandran, M.,Kozieradzki, I.,Cossar, D.,Schapira, M.,Arrowsmith, C.H.,Bountra, C.,Weigelt, J.,Edwards, A.M.,Wyatt, P.G.,Ferguson, M.A.J.,Frearson, J.A.,Brand, S.Y.,Robinson, D.A.,Bochkarev, A.,Hui, R.,Structural Genomics Consortium (SGC) (deposition date: 2009-09-02, release date: 2009-09-15, Last modification date: 2024-02-21) |
Primary citation | Qiu, W.,Hutchinson, A.,Wernimont, A.,Lin, Y.-H.,Kania, A.,Ravichandran, M.,Kozieradzki, I.,Cossar, D.,Schapira, M.,Arrowsmith, C.H.,Bountra, C.,Weigelt, J.,Edwards, A.M.,Wyatt, P.G.,Ferguson, M.A.J.,Frearson, J.A.,Brand, S.Y.,Robinson, D.A.,Bochkarev, A.,Hui, R. Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD85646 To be Published, |
Experimental method |
Structure validation
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