3IWE
Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD85646
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glycylpeptide N-tetradecanoyltransferase 1 | polymer | 383 | 44541.3 | 2 | UniProt (P30419) Pfam (PF01233) Pfam (PF02799) | Homo sapiens (human) | Peptide N-myristoyltransferase 1, Myristoyl-CoA:protein N-myristoyltransferase 1, NMT 1, Type I N-myristoyltransferase |
| 2 | C, E (A, B) | TETRADECANOYL-COA | non-polymer | 977.9 | 2 | Chemie (MYA) | |||
| 3 | D, F (A, B) | 2,6-dichloro-4-(2-piperazin-1-ylpyridin-4-yl)-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide | non-polymer | 495.4 | 2 | Chemie (646) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 935 | Chemie (HOH) |
Sequence modifications
A, B: 115 - 496 (UniProt: P30419)
| PDB | External Database | Details |
|---|---|---|
| Gly 114 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 89082.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2946.6 | |
| All* | Total formula weight | 92029.3 |
