PDB: 74387 resultsInfo pagesStatus searchChemie searchBIRD

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7WAL	Glutamyl-tRNA synthetase from Plasmodium falciparum (PfERS) in complex with Co Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, COBALT (II) ION, ... Authors: Sharma, V, Manickam, Y, Babbar, P, Sharma, A. Deposit date: 2021-12-14 Release date: 2022-12-21 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Structural characterization of glutamyl-tRNA synthetase (GluRS) from Plasmodium falciparum. Mol.Biochem.Parasitol., 253, 2022
7WAJ	Glutamyl-tRNA synthetase from Plasmodium falciparum (PfERS) complexed with ATP and Co Descriptor: ADENOSINE-5'-TRIPHOSPHATE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... Authors: Sharma, V, Manickam, Y, Babbar, P, Sharma, A. Deposit date: 2021-12-14 Release date: 2022-12-21 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.254 Å) Cite: Structural characterization of glutamyl-tRNA synthetase (GluRS) from Plasmodium falciparum. Mol.Biochem.Parasitol., 253, 2022
7WAI	Glutamyl-tRNA synthetase from Plasmodium falciparum (PfERS) Descriptor: CHLORIDE ION, Glutamyl-tRNA synthetase Authors: Sharma, V, Manickam, Y, Harlos, K, Sharma, A. Deposit date: 2021-12-14 Release date: 2022-12-21 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.105 Å) Cite: Structural characterization of glutamyl-tRNA synthetase (GluRS) from Plasmodium falciparum. Mol.Biochem.Parasitol., 253, 2022
7WAO	Glutamyl-tRNA synthetase from Plasmodium falciparum (PfERS) in complex with Mn Descriptor: CHLORIDE ION, Glutamyl-tRNA synthetase, MANGANESE (II) ION Authors: Sharma, V, Manickam, Y, Babbar, P, Sharma, A. Deposit date: 2021-12-14 Release date: 2022-12-21 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.582 Å) Cite: Structural characterization of glutamyl-tRNA synthetase (GluRS) from Plasmodium falciparum. Mol.Biochem.Parasitol., 253, 2022
7WRU	Crystal structure of the apo chicken glutamyl-tRNA synthetase 1 (EARS1) Descriptor: Glutamyl-tRNA synthetase, MERCURY (II) ION Authors: Chung, S, Cho, Y. Deposit date: 2022-01-27 Release date: 2022-11-23 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Regulation of BRCA1 stability through the tandem UBX domains of isoleucyl-tRNA synthetase 1. Nat Commun, 13, 2022
7WPT	Methionyl-tRNA synthetase from Staphylococcus aureus complexed with a fragment M2-80 and ATP Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ... Authors: Yi, J, Cai, Z, Qiu, H, Lu, F, Chen, B, Luo, Z, Gu, Q, Xu, J, Zhou, H. Deposit date: 2022-01-24 Release date: 2022-04-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.26 Å) Cite: Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetase. Nucleic Acids Res., 50, 2022
7WPX	Methionyl-tRNA synthetase from Staphylococcus aureus complexed with a fragment and ATP Descriptor: 1,2-ETHANEDIOL, 6-chloranylimidazo[2,1-b][1,3]thiazole, ADENOSINE-5'-TRIPHOSPHATE, ... Authors: Yi, J, Cai, Z, Qiu, H, Lu, F, Chen, B, Luo, Z, Gu, Q, Xu, J, Zhou, H. Deposit date: 2022-01-24 Release date: 2022-04-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetase. Nucleic Acids Res., 50, 2022
7WQ0	Methionyl-tRNA synthetase from Staphylococcus aureus complexed with a fragment and ATP Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Methionine--tRNA ligase, ... Authors: Yi, J, Cai, Z, Qiu, H, Lu, F, Chen, B, Luo, Z, Gu, Q, Xu, J, Zhou, H. Deposit date: 2022-01-24 Release date: 2022-04-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.09 Å) Cite: Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetase. Nucleic Acids Res., 50, 2022
7WPL	Methionyl-tRNA synthetase from Staphylococcus aureus complexed with ATP Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Methionine--tRNA ligase Authors: Yi, J, Cai, Z, Qiu, H, Lu, F, Chen, B, Luo, Z, Gu, Q, Xu, J, Zhou, H. Deposit date: 2022-01-24 Release date: 2022-04-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetase. Nucleic Acids Res., 50, 2022
7WPM	Methionyl-tRNA synthetase from Staphylococcus aureus complexed with a fragment and ATP Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Methionine--tRNA ligase, ... Authors: Yi, J, Cai, Z, Qiu, H, Lu, F, Chen, B, Luo, Z, Gu, Q, Xu, J, Zhou, H. Deposit date: 2022-01-24 Release date: 2022-04-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetase. Nucleic Acids Res., 50, 2022
7WPN	Methionyl-tRNA synthetase from Staphylococcus aureus complexed with a phenylbenzimidazole inhibitor and ATP Descriptor: (phenylmethyl) N-[(2R)-2-[2-(4-bromanyl-3-oxidanyl-phenyl)-5-(methylcarbamoyl)benzimidazol-1-yl]-2-(3,4-dimethoxyphenyl)ethyl]carbamate, 1,2-ETHANEDIOL, ACETIC ACID, ... Authors: Yi, J, Cai, Z, Qiu, H, Lu, F, Chen, B, Luo, Z, Gu, Q, Xu, J, Zhou, H. Deposit date: 2022-01-24 Release date: 2022-04-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetase. Nucleic Acids Res., 50, 2022
7WPJ	Methionyl-tRNA synthetase from Staphylococcus aureus Descriptor: 1,2-ETHANEDIOL, Methionine--tRNA ligase Authors: Yi, J, Cai, Z, Qiu, H, Lu, F, Chen, B, Luo, Z, Gu, Q, Xu, J, Zhou, H. Deposit date: 2022-01-24 Release date: 2022-04-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetase. Nucleic Acids Res., 50, 2022
7WPI	Methionyl-tRNA synthetase from Staphylococcus aureus complexed with a phenylbenzimidazole inhibitor Descriptor: 1,2-ETHANEDIOL, 2-(4-bromanyl-3-oxidanyl-phenyl)-1-[(1R)-2-[2-(2-tert-butylphenoxy)ethanoylamino]-1-(3,4-dimethoxyphenyl)ethyl]-N-methyl-benzimidazole-5-carboxamide, ACETATE ION, ... Authors: Yi, J, Cai, Z, Qiu, H, Lu, F, Chen, B, Luo, Z, Gu, Q, Xu, J, Zhou, H. Deposit date: 2022-01-24 Release date: 2022-04-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.92 Å) Cite: Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetase. Nucleic Acids Res., 50, 2022
7WPK	Methionyl-tRNA synthetase from Staphylococcus aureus complexed with L-Met Descriptor: METHIONINE, Methionine--tRNA ligase Authors: Yi, J, Cai, Z, Qiu, H, Lu, F, Chen, B, Luo, Z, Gu, Q, Xu, J, Zhou, H. Deposit date: 2022-01-24 Release date: 2022-04-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetase. Nucleic Acids Res., 50, 2022
3ND3	Uhelix 16-mer dsRNA Descriptor: 5'-R(*AP*GP*AP*GP*AP*AP*GP*AP*UP*UP*UP*UP*UP*UP*UP*U)-3', POTASSIUM ION, SODIUM ION Authors: Mooers, B.H, Singh, A. Deposit date: 2010-06-07 Release date: 2011-09-21 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.37 Å) Cite: The crystal structure of an oligo(U):pre-mRNA duplex from a trypanosome RNA editing substrate. Rna, 17, 2011
3ND4	Watson-Crick 16-mer dsRNA Descriptor: 5'-R(*AP*GP*AP*GP*AP*AP*GP*AP*UP*CP*UP*UP*CP*UP*CP*U)-3', MAGNESIUM ION, POTASSIUM ION, ... Authors: Mooers, B.H, Singh, A. Deposit date: 2010-06-07 Release date: 2011-09-21 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.524 Å) Cite: The crystal structure of an oligo(U):pre-mRNA duplex from a trypanosome RNA editing substrate. Rna, 17, 2011
6DCL	Crystal structure of UP1 bound to pri-miRNA-18a terminal loop Descriptor: 1,2-ETHANEDIOL, Heterogeneous nuclear ribonucleoprotein A1, RNA (5'-R(*AP*GP*UP*AP*GP*AP*UP*UP*AP*GP*C)-3') Authors: Kooshapur, H, Sattler, M. Deposit date: 2018-05-07 Release date: 2018-06-27 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.497 Å) Cite: Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1. Nat Commun, 9, 2018
1A8H	METHIONYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS Descriptor: METHIONYL-TRNA SYNTHETASE, ZINC ION Authors: Sugiura, I, Nureki, O, Ugaji, Y, Kuwabara, S, Lober, B, Giege, R, Moras, D, Yokoyama, S, Konno, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 1998-03-26 Release date: 1999-05-04 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: The 2.0 A crystal structure of Thermus thermophilus methionyl-tRNA synthetase reveals two RNA-binding modules. Structure, 8, 2000
5K0S	Crystal structure of methionyl-tRNA synthetase MetRS from Brucella melitensis in complex with inhibitor Chem 1312 Descriptor: 2-({3-[(3,5-dichlorobenzyl)amino]propyl}amino)quinolin-4(1H)-one, Methionine--tRNA ligase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2016-05-17 Release date: 2016-05-25 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis. Plos One, 11, 2016
4KR2	Glycyl-tRNA synthetase in complex with tRNA-Gly Descriptor: ADENOSINE MONOPHOSPHATE, Gly-tRNA-CCC, Glycine--tRNA ligase Authors: Qin, X, Hao, Z, Tian, Q, Zhang, Z, Zhou, C, Xie, W. Deposit date: 2013-05-16 Release date: 2014-05-21 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.292 Å) Cite: Cocrystal Structures of Glycyl-tRNA Synthetase in Complex with tRNA Suggest Multiple Conformational States in Glycylation J.Biol.Chem., 289, 2014
5K0T	Crystal structure of methionyl-tRNA synthetase MetRS from Brucella melitensis in complex with inhibitor Chem 1415 Descriptor: 1,2-ETHANEDIOL, 1-{3-[(3-chloro-5-methoxybenzyl)amino]propyl}-3-phenylurea, Methionine--tRNA ligase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2016-05-17 Release date: 2016-05-25 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis. Plos One, 11, 2016
4KR3	Glycyl-tRNA synthetase mutant E71G in complex with tRNA-Gly Descriptor: GLYCINE, Gly-tRNA-CCC, Glycine--tRNA ligase, ... Authors: Qin, X, Hao, Z, Tian, Q, Zhang, Z, Zhou, C, Xie, W. Deposit date: 2013-05-16 Release date: 2014-05-21 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (3.235 Å) Cite: Cocrystal Structures of Glycyl-tRNA Synthetase in Complex with tRNA Suggest Multiple Conformational States in Glycylation J.Biol.Chem., 289, 2014
3VJR	Crystal structure of Peptidyl-tRNA hydrolase from Escherichia coli in complex with the CCA-acceptor-T[PSI]C domain of tRNA Descriptor: Peptidyl-tRNA hydrolase, tRNA CCA-acceptor Authors: Ito, K, Murakami, R, Mochizuki, M, Qi, H, Shimizu, Y, Miura, K.I, Ueda, T, Uchiumi, T. Deposit date: 2011-10-28 Release date: 2012-09-12 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural basis for the substrate recognition and catalysis of peptidyl-tRNA hydrolase. Nucleic Acids Res., 40, 2012
4PY2	Crystal structure of methionyl-tRNA synthetase MetRS from Brucella melitensis in complex with inhibitor 1-{3-[(3,5-DICHLOROBENZYL)AMINO]PROPYL}-3-THIOPHEN-3-YLUREA Descriptor: 1,2-ETHANEDIOL, 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-thiophen-3-ylurea, Methionine--tRNA ligase Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2014-03-25 Release date: 2015-04-15 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis. Plos One, 11, 2016
4Q2Y	Crystal structure of Arginyl-tRNA synthetase Descriptor: Arginine--tRNA ligase, cytoplasmic Authors: Kim, H.S, Jo, C.H, Cha, S.Y, Han, A.R, Hwang, K.Y. Deposit date: 2014-04-10 Release date: 2014-07-23 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.799 Å) Cite: The crystal structure of arginyl-tRNA synthetase from Homo sapiens Febs Lett., 588, 2014

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