3G4F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3g4f by Molmil](/molmil-images/mine/3g4f) | Crystal Structure of (+)- -Cadinene Synthase from Gossypium arboreum in complex with 2-fluorofarnesyl diphosphate | Descriptor: | (+)-delta-cadinene synthase isozyme XC1, (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, BETA-MERCAPTOETHANOL, ... | Authors: | Gennadios, H.A, Di Costanzo, L, Christianson, D.W. | Deposit date: | 2009-02-03 | Release date: | 2009-06-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.651 Å) | Cite: | Crystal structure of (+)-delta-cadinene synthase from Gossypium arboreum and evolutionary divergence of metal binding motifs for catalysis. Biochemistry, 48, 2009
|
|
3EZO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ezo by Molmil](/molmil-images/mine/3ezo) | |
3EY4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ey4 by Molmil](/molmil-images/mine/3ey4) | Further studies with the 2-amino-1,3-thiazol-4(5H)-one class of 11-hydroxysteroid dehydrogenase type 1 (11-HSD1) inhibitors: Reducing pregnane X receptor (PXR) activity and exploring activity in a monkey pharmacodynamic model | Descriptor: | (5S)-2-{[(1S)-1-(4-fluorophenyl)ethyl]amino}-5-(1-hydroxy-1-methylethyl)-5-methyl-1,3-thiazol-4(5H)-one, 11-beta-Hydroxysteroid Dehydrogenase 1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Zhang, J.D, Jordan, S.R, Li, V. | Deposit date: | 2008-10-17 | Release date: | 2008-11-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Further studies with the 2-amino-1,3-thiazol-4(5H)-one class of 11-hydroxysteroid dehydrogenase type 1 (11-HSD1) inhibitors: Reducing pregnane X receptor (PXR) activity and exploring activity in a monkey pharmacodynamic model To be Published, 2008
|
|
3G50
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3g50 by Molmil](/molmil-images/mine/3g50) | Crystal Structure of NiSOD D3A mutant at 1.9 A | Descriptor: | NICKEL (II) ION, Superoxide dismutase [Ni] | Authors: | Garman, S.C, Guce, A.I, Herbst, R.W, Bryngelson, P.A, Cabelli, D.E, Higgins, K.A, Ryan, K.C, Maroney, M.J. | Deposit date: | 2009-02-04 | Release date: | 2009-04-28 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Role of conserved tyrosine residues in NiSOD catalysis: a case of convergent evolution Biochemistry, 48, 2009
|
|
3G7K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3g7k by Molmil](/molmil-images/mine/3g7k) | |
3G81
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3g81 by Molmil](/molmil-images/mine/3g81) | |
3FLR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3flr by Molmil](/molmil-images/mine/3flr) | |
3FPT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3fpt by Molmil](/molmil-images/mine/3fpt) | The Crystal Structure of the Complex between Evasin-1 and CCL3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Evasin-1 | Authors: | Shaw, J.P, Dias, J.M. | Deposit date: | 2009-01-06 | Release date: | 2010-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of chemokine sequestration by a tick chemokine binding protein: the crystal structure of the complex between Evasin-1 and CCL3 Plos One, 4, 2009
|
|
3FQ4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3fq4 by Molmil](/molmil-images/mine/3fq4) | |
3GMT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gmt by Molmil](/molmil-images/mine/3gmt) | Crystal structure of adenylate kinase from burkholderia pseudomallei | Descriptor: | Adenylate kinase, SULFATE ION | Authors: | Abendroth, J, Staker, B.L, Robinson, H, Buchko, G.W, Hewitt, S.N, Napuli, A.J, Van Voorhis, W, Stacy, R, Myler, P.J, Stewart, L, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2009-03-15 | Release date: | 2009-06-02 | Last modified: | 2013-10-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural characterization of Burkholderia pseudomallei adenylate kinase (Adk): profound asymmetry in the crystal structure of the 'open' state. Biochem.Biophys.Res.Commun., 394, 2010
|
|
3GT9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gt9 by Molmil](/molmil-images/mine/3gt9) | Structure of an ML-IAP/XIAP chimera bound to a peptidomimetic | Descriptor: | Baculoviral IAP repeat-containing 7, N-{(1S)-1-cyclohexyl-2-[(2S)-2-(4-naphthalen-1-yl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-2-oxoethyl}-N~2~-methyl-L-alaninamide, ZINC ION | Authors: | Franklin, M.C, Fairbrother, W.J, Cohen, F. | Deposit date: | 2009-03-27 | Release date: | 2010-03-09 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Antagonists of inhibitor of apoptosis proteins based on thiazole amide isosteres. Bioorg.Med.Chem.Lett., 20, 2010
|
|
3GVF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gvf by Molmil](/molmil-images/mine/3gvf) | |
3GW3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gw3 by Molmil](/molmil-images/mine/3gw3) | human UROD mutant K297N | Descriptor: | Uroporphyrinogen decarboxylase | Authors: | Hill, C.P, Phillips, J.D, Whitby, F.G, Warby, C, Kushner, J.P. | Deposit date: | 2009-03-31 | Release date: | 2009-07-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and kinetic characterization of mutant human uroporphyrinogen decarboxylases. Cell Mol Biol (Noisy-le-grand), 55, 2009
|
|
3H5H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3h5h by Molmil](/molmil-images/mine/3h5h) | |
3GW0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gw0 by Molmil](/molmil-images/mine/3gw0) | UROD mutant G318R | Descriptor: | Uroporphyrinogen decarboxylase | Authors: | Hill, C.P, Phillips, J.D, Whitby, F.G, Warby, C, Kushner, J.P. | Deposit date: | 2009-03-31 | Release date: | 2009-07-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and kinetic characterization of mutant human uroporphyrinogen decarboxylases. Cell Mol Biol (Noisy-le-grand), 55, 2009
|
|
7YX9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7yx9 by Molmil](/molmil-images/mine/7yx9) | |
7Z8E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z8e by Molmil](/molmil-images/mine/7z8e) | Crystal structure of the substrate-binding protein YejA from S. meliloti in complex with peptide fragment | Descriptor: | 1,2-ETHANEDIOL, ABC transporter substrate-binding protein, GLY-SER-ASP-VAL-ALA, ... | Authors: | Morera, S, Vigouroux, V, Travin, D.Y. | Deposit date: | 2022-03-17 | Release date: | 2023-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Dual-Uptake Mode of the Antibiotic Phazolicin Prevents Resistance Acquisition by Gram-Negative Bacteria. Mbio, 14, 2023
|
|
7YXB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7yxb by Molmil](/molmil-images/mine/7yxb) | MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange | Descriptor: | 1,2-ETHANEDIOL, CITRATE ANION, CLIP peptide, ... | Authors: | Roske, Y, Abualrous, E.T, Freund, C. | Deposit date: | 2022-02-15 | Release date: | 2023-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.095 Å) | Cite: | MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange. Nat.Chem.Biol., 19, 2023
|
|
7Z0Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z0q by Molmil](/molmil-images/mine/7z0q) | MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange | Descriptor: | 1,2-ETHANEDIOL, CLIP peptide, HLA class II histocompatibility antigen, ... | Authors: | Roske, Y, Abualrous, E.T, Freund, C. | Deposit date: | 2022-02-23 | Release date: | 2023-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange. Nat.Chem.Biol., 19, 2023
|
|
7VUZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vuz by Molmil](/molmil-images/mine/7vuz) | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with PAMP-12, state2 | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Li, Y, Yang, F. | Deposit date: | 2021-11-04 | Release date: | 2021-12-01 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Structure, function and pharmacology of human itch receptor complexes. Nature, 600, 2021
|
|
7VV4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vv4 by Molmil](/molmil-images/mine/7vv4) | |
7VV5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vv5 by Molmil](/molmil-images/mine/7vv5) | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with C48/80, state1 | Descriptor: | 2-[4-methoxy-3-[[2-methoxy-3-[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-5-[2-(methylamino)ethyl]phenyl]methyl]phenyl]-~{N}-methyl-ethanamine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Li, Y, Yang, F. | Deposit date: | 2021-11-04 | Release date: | 2021-12-01 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Structure, function and pharmacology of human itch receptor complexes. Nature, 600, 2021
|
|
7VDH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vdh by Molmil](/molmil-images/mine/7vdh) | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with C48/80, state2 | Descriptor: | 2-[4-methoxy-3-[[2-methoxy-3-[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-5-[2-(methylamino)ethyl]phenyl]methyl]phenyl]-~{N}-methyl-ethanamine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Li, Y, Yang, F. | Deposit date: | 2021-09-07 | Release date: | 2021-12-01 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure, function and pharmacology of human itch receptor complexes. Nature, 600, 2021
|
|
7VV0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vv0 by Molmil](/molmil-images/mine/7vv0) | |
7VV6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vv6 by Molmil](/molmil-images/mine/7vv6) | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with C48/80 (local) | Descriptor: | 2-[4-methoxy-3-[[2-methoxy-3-[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-5-[2-(methylamino)ethyl]phenyl]methyl]phenyl]-~{N}-methyl-ethanamine, CHOLESTEROL, Mas-related G-protein coupled receptor member X2 | Authors: | Li, Y, Yang, F. | Deposit date: | 2021-11-04 | Release date: | 2021-12-01 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure, function and pharmacology of human itch receptor complexes. Nature, 600, 2021
|
|