6IV5
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![BU of 6iv5 by Molmil](/molmil-images/mine/6iv5) | Crystal structure of arabidopsis N6-mAMP deaminase MAPDA | Descriptor: | Adenosine/AMP deaminase family protein, PHOSPHATE ION, ZINC ION | Authors: | Wu, B.X, Zhang, D, Nie, H.B, Shen, S.L, Li, S.S, Patel, D.J. | Deposit date: | 2018-12-02 | Release date: | 2019-02-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.749 Å) | Cite: | Structure ofArabidopsis thaliana N6-methyl-AMP deaminase ADAL with bound GMP and IMP and implications forN6-methyl-AMP recognition and processing. Rna Biol., 16, 2019
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2OOE
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![BU of 2ooe by Molmil](/molmil-images/mine/2ooe) | Crystal structure of HAT domain of murine CstF-77 | Descriptor: | Cleavage stimulation factor 77 kDa subunit | Authors: | Bai, Y, Auperin, T.C, Chou, C.-Y, Chang, G.-G, Manley, J.L, Tong, L. | Deposit date: | 2007-01-25 | Release date: | 2007-04-10 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal Structure of Murine CstF-77: Dimeric Association and Implications for Polyadenylation of mRNA Precursors. Mol.Cell, 25, 2007
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2OND
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![BU of 2ond by Molmil](/molmil-images/mine/2ond) | Crystal Structure of the HAT-C domain of murine CstF-77 | Descriptor: | Cleavage stimulation factor 77 kDa subunit | Authors: | Bai, Y, Auperin, T.C, Chou, C.-Y, Chang, G.-G, Manley, J.L, Tong, L. | Deposit date: | 2007-01-23 | Release date: | 2007-04-10 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of Murine CstF-77: Dimeric Association and Implications for Polyadenylation of mRNA Precursors. Mol.Cell, 25, 2007
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3GXQ
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![BU of 3gxq by Molmil](/molmil-images/mine/3gxq) | Structure of ArtA and DNA complex | Descriptor: | DNA (5'-D(*AP*CP*AP*TP*GP*AP*CP*AP*TP*G)-3'), DNA (5'-D(*AP*CP*AP*TP*GP*TP*CP*AP*TP*GP*T)-3'), Putative regulator of transfer genes ArtA | Authors: | Ni, L, Firth, N, Schumacher, M.A. | Deposit date: | 2009-04-02 | Release date: | 2009-10-13 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The Staphylococcus aureus pSK41 plasmid-encoded ArtA protein is a master regulator of plasmid transmission genes and contains a RHH motif used in alternate DNA-binding modes. Nucleic Acids Res., 37, 2009
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1C0O
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![BU of 1c0o by Molmil](/molmil-images/mine/1c0o) | |
3O8D
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![BU of 3o8d by Molmil](/molmil-images/mine/3o8d) | |
4WJS
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![BU of 4wjs by Molmil](/molmil-images/mine/4wjs) | |
3JD7
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![BU of 3jd7 by Molmil](/molmil-images/mine/3jd7) | The novel asymmetric entry intermediate of a picornavirus captured with nanodiscs | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Lee, H, Shingler, K.L, Organtini, L.J, Ashley, R.E, Makhov, A.M, Conway, J.F, Hafenstein, S. | Deposit date: | 2016-04-29 | Release date: | 2016-09-14 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | The novel asymmetric entry intermediate of a picornavirus captured with nanodiscs. Sci Adv, 2, 2016
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6PUQ
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6BID
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![BU of 6bid by Molmil](/molmil-images/mine/6bid) | 1.15 A resolution structure of Norovirus 3CL protease in complex with a triazole-based macrocyclic inhibitor | Descriptor: | 3C-like protease, benzyl [(8S,11S,14S)-11-(cyclohexylmethyl)-8-(hydroxymethyl)-5,10,13-trioxo-1,4,9,12,17,18-hexaazabicyclo[14.2.1]nonadeca-16(19),17-dien-14-yl]carbamate | Authors: | Lovell, S, Battaile, K.P, Mehzabeen, N, Kankanamalage, A.C.G, Weerawarna, P.M, Rathnayake, A.D, Kim, Y, Chang, K.O, Groutas, W.C. | Deposit date: | 2017-11-01 | Release date: | 2018-11-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Putative structural rearrangements associated with the interaction of macrocyclic inhibitors with norovirus 3CL protease. Proteins, 87, 2019
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3Q3Y
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![BU of 3q3y by Molmil](/molmil-images/mine/3q3y) | Complex structure of HEVB EV93 main protease 3C with Compound 1 (AG7404) | Descriptor: | 1,2-ETHANEDIOL, AMMONIUM ION, HEVB EV93 3C protease, ... | Authors: | Costenaro, L, Kaczmarska, Z, Arnan, C, Sola, M, Coutard, B, Norder, H, Canard, B, Coll, M. | Deposit date: | 2010-12-22 | Release date: | 2011-09-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | Structural Basis for Antiviral Inhibition of the Main Protease, 3C, from Human Enterovirus 93. J.Virol., 85, 2011
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4WJV
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![BU of 4wjv by Molmil](/molmil-images/mine/4wjv) | Crystal structure of Rsa4 in complex with the Nsa2 binding peptide | Descriptor: | Maltose-binding periplasmic protein, Ribosome assembly protein 4, Ribosome biogenesis protein NSA2, ... | Authors: | Holdermann, I, Paternoga, H, Bassler, J, Hurt, E, Sinning, I. | Deposit date: | 2014-10-01 | Release date: | 2014-11-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation. J.Cell Biol., 207, 2014
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6PUP
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3GDH
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![BU of 3gdh by Molmil](/molmil-images/mine/3gdh) | Methyltransferase domain of human Trimethylguanosine Synthase 1 (TGS1) bound to m7GTP and adenosyl-homocysteine (active form) | Descriptor: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, R-1,2-PROPANEDIOL, S-1,2-PROPANEDIOL, ... | Authors: | Monecke, T, Dickmanns, A, Ficner, R. | Deposit date: | 2009-02-24 | Release date: | 2009-06-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for m7G-cap hypermethylation of small nuclear, small nucleolar and telomerase RNA by the dimethyltransferase TGS1. Nucleic Acids Res., 37, 2009
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6BIC
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![BU of 6bic by Molmil](/molmil-images/mine/6bic) | 2.25 A resolution structure of Norovirus 3CL protease in complex with a triazole-based macrocyclic inhibitor | Descriptor: | (phenylmethyl) ~{N}-[(9~{S},12~{S},15~{S})-9-(hydroxymethyl)-12-(2-methylpropyl)-6,11,14-tris(oxidanylidene)-1,5,10,13,18,19-hexazabicyclo[15.2.1]icosa-17(20),18-dien-15-yl]carbamate, 3C-like protease | Authors: | Lovell, S, Battaile, K.P, Mehzabeen, N, Kankanamalage, A.C.G, Weerawarna, P.M, Rathnayake, A.D, Kim, Y, Chang, K.O, Groutas, W.C. | Deposit date: | 2017-11-01 | Release date: | 2018-11-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Putative structural rearrangements associated with the interaction of macrocyclic inhibitors with norovirus 3CL protease. Proteins, 87, 2019
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6BIB
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![BU of 6bib by Molmil](/molmil-images/mine/6bib) | 1.95 A resolution structure of Norovirus 3CL protease in complex with a triazole-based macrocyclic inhibitor | Descriptor: | 3C-like protease, benzyl [(9S,12S,15S)-12-(cyclohexylmethyl)-9-(hydroxymethyl)-6,11,14-trioxo-1,5,10,13,18,19-hexaazabicyclo[15.2.1]icosa-17(20),18-dien-15-yl]carbamate | Authors: | Lovell, S, Battaile, K.P, Mehzabeen, N, Kankanamalage, A.C.G, Weerawarna, P.M, Rathnayake, A.D, Kim, Y, Chang, K.O, Groutas, W.C. | Deposit date: | 2017-11-01 | Release date: | 2018-11-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Putative structural rearrangements associated with the interaction of macrocyclic inhibitors with norovirus 3CL protease. Proteins, 87, 2019
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5UKI
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4GEK
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![BU of 4gek by Molmil](/molmil-images/mine/4gek) | Crystal Structure of wild-type CmoA from E.coli | Descriptor: | (2S)-4-[{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}(carboxylatomethyl)sulfonio] -2-ammoniobutanoate, SULFATE ION, tRNA (cmo5U34)-methyltransferase | Authors: | Kim, J, Toro, R, Bonanno, J.B, Bhosle, R, Sampathkumar, P, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2012-08-02 | Release date: | 2012-10-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure-guided discovery of the metabolite carboxy-SAM that modulates tRNA function Nature, 498, 2013
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2A0C
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![BU of 2a0c by Molmil](/molmil-images/mine/2a0c) | Human CDK2 in complex with olomoucine II, a novel 2,6,9-trisubstituted purine cyclin-dependent kinase inhibitor | Descriptor: | 2-{[(2-{[(1R)-1-(HYDROXYMETHYL)PROPYL]AMINO}-9-ISOPROPYL-9H-PURIN-6-YL)AMINO]METHYL}PHENOL, Cell division protein kinase 2 | Authors: | Krystof, V, McNae, I.W, Walkinshaw, M.D, Fischer, P.M, Muller, P, Vojtesek, B, Orsag, M, Havlicek, L, Strnad, M. | Deposit date: | 2005-06-16 | Release date: | 2006-01-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Antiproliferative activity of olomoucine II, a novel 2,6,9-trisubstituted purine cyclin-dependent kinase inhibitor Cell.Mol.Life Sci., 62, 2005
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1OZM
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![BU of 1ozm by Molmil](/molmil-images/mine/1ozm) | Y106F mutant of Z. mobilis TGT | Descriptor: | Queuine tRNA-ribosyltransferase, ZINC ION | Authors: | Brenk, R, Stubbs, M.T, Heine, A, Reuter, K, Klebe, G. | Deposit date: | 2003-04-09 | Release date: | 2003-09-30 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Flexible adaptations in the structure of the tRNA-modifying enzyme
tRNA-guanine transglycosylase and their implications for substrate selectivity,
reaction mechanism and structure-based drug design Chembiochem, 4, 2003
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4MEM
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![BU of 4mem by Molmil](/molmil-images/mine/4mem) | Crystal Structure of the rat USP11 DUSP-UBL domains | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 11 | Authors: | Harper, S, Gratton, H.E, Cornaciu, I, Oberer, M, Scott, D.J, Emsley, J, Dreveny, I. | Deposit date: | 2013-08-27 | Release date: | 2014-05-07 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Structure and Catalytic Regulatory Function of Ubiquitin Specific Protease 11 N-Terminal and Ubiquitin-like Domains. Biochemistry, 53, 2014
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3J06
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![BU of 3j06 by Molmil](/molmil-images/mine/3j06) | CryoEM Helical Reconstruction of TMV | Descriptor: | 5'-R(P*AP*UP*G)-3', Coat protein | Authors: | Ge, P, Zhou, Z.H. | Deposit date: | 2011-04-26 | Release date: | 2011-06-01 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Hydrogen-bonding networks and RNA bases revealed by cryo electron microscopy suggest a triggering mechanism for calcium switches. Proc.Natl.Acad.Sci.USA, 108, 2011
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1K6O
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![BU of 1k6o by Molmil](/molmil-images/mine/1k6o) | Crystal Structure of a Ternary SAP-1/SRF/c-fos SRE DNA Complex | Descriptor: | 5'-D(*CP*AP*CP*AP*GP*GP*AP*TP*GP*TP*CP*CP*AP*TP*AP*TP*TP*AP*GP*GP*AP*CP*A)-3', 5'-D(*TP*GP*TP*CP*CP*TP*AP*AP*TP*AP*TP*GP*GP*AP*CP*AP*TP*CP*CP*TP*GP*TP*G)-3', ETS-domain protein ELK-4, ... | Authors: | Mo, Y, Ho, W, Johnston, K, Marmorstein, R. | Deposit date: | 2001-10-16 | Release date: | 2002-01-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | Crystal structure of a ternary SAP-1/SRF/c-fos SRE DNA complex. J.Mol.Biol., 314, 2001
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6G04
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![BU of 6g04 by Molmil](/molmil-images/mine/6g04) | NMR Solution Structure of Yeast TSR2(1-152) in Complex with S26A(100-119) | Descriptor: | 40S ribosomal protein S26-A, Pre-rRNA-processing protein TSR2 | Authors: | Michel, E, Schuetz, S, Damberger, F.F, Allain, F.H.-T, Panse, V.G. | Deposit date: | 2018-03-16 | Release date: | 2018-09-19 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2. Nat Commun, 9, 2018
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1XUX
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![BU of 1xux by Molmil](/molmil-images/mine/1xux) | Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogs | Descriptor: | DNA (5'-D(*GP*CP*GP*TP*AP*(NMS)P*AP*CP*GP*C)-3') | Authors: | Pattanayek, R, Sethaphong, L, Pan, C, Prhavc, M, Prakash, T.P, Manoharan, M, Egli, M. | Deposit date: | 2004-10-26 | Release date: | 2004-12-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogues. J.Am.Chem.Soc., 126, 2004
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