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5UKI
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BU of 5uki by Molmil
Mn2+ and Zn2+ requirements for the lariat debranching enzyme, Dbr1
Descriptor: MANGANESE (II) ION, RNA lariat debranching enzyme, putative, ...
Authors:Macbeth, M.R, Ransey, L.
Deposit date:2017-01-22
Release date:2018-02-21
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn2+/Mn2+heterobinucleation.
FEBS Lett., 591, 2017
2NPZ
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BU of 2npz by Molmil
Crystal structure of junctioned hairpin ribozyme incorporating synthetic propyl linker
Descriptor: 5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*G)-3', ...
Authors:MacElrevey, C, Krucinska, J, Wedekind, J.E.
Deposit date:2006-10-30
Release date:2007-08-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:A posteriori design of crystal contacts to improve the X-ray diffraction properties of a small RNA enzyme.
Acta Crystallogr.,Sect.D, 63, 2007
1MDG
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BU of 1mdg by Molmil
An Alternating Antiparallel Octaplex in an RNA Crystal Structure
Descriptor: 5'-R(*UP*(BGM)GP*AP*GP*GP*U)-3', COBALT HEXAMMINE(III), SODIUM ION
Authors:Pan, B.C, Xiong, Y, Shi, K, Sundaralingam, M.
Deposit date:2002-08-07
Release date:2003-08-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:An Eight-Stranded Helical Fragment in RNA Crystal Structure: Implications for Tetraplex Interaction
Structure, 11, 2003
1R6Z
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BU of 1r6z by Molmil
The Crystal Structure of the Argonaute2 PAZ domain (as a MBP fusion)
Descriptor: Chimera of Maltose-binding periplasmic protein and Argonaute 2, NICKEL (II) ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Song, J.J, Liu, J, Tolia, N.H, Schneiderman, J, Smith, S.K, Martienssen, R.A, Hannon, G.J, Joshua-Tor, L.
Deposit date:2003-10-17
Release date:2004-01-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes.
Nat.Struct.Biol., 10, 2003
5MFX
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BU of 5mfx by Molmil
Zika NS3 helicase:RNA complex
Descriptor: ACETATE ION, CITRATE ANION, Genome polyprotein, ...
Authors:Jenkins, H.T, Ge, M, Chechik, M, Greive, S.J, Antson, A.A.
Deposit date:2016-11-18
Release date:2017-01-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.598 Å)
Cite:How Zika virus NS3 helicase grips the first nucleotide of the leading RNA strand
To Be Published
4IQZ
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BU of 4iqz by Molmil
The crystal structure of a large insert in RNA polymerase (RpoC) subunit from E. coli
Descriptor: DNA-directed RNA polymerase subunit beta', IODIDE ION, SODIUM ION
Authors:Bhandari, V, Sugiman-Marangos, S.N, Naushad, H.S, Gupta, R.S, Junop, M.S.
Deposit date:2013-01-14
Release date:2013-02-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of a large insert in RNA polymerase (RpoC) subunit from E. coli
To be Published
2BEX
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BU of 2bex by Molmil
Crystal structure of Placental Ribonuclease Inhibitor in complex with Human Eosinophil Derived Neurotoxin at 2A resolution
Descriptor: ALPHA-KETOMALONIC ACID, GLYCEROL, NONSECRETORY RIBONUCLEASE, ...
Authors:Iyer, S, Holloway, D.E, Kumar, K, Shapiro, R, Acharya, K.R.
Deposit date:2004-12-01
Release date:2005-03-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Molecular Recognition of Human Eosinophil-Derived Neurotoxin (Rnase 2) by Placental Ribonuclease Inhibitor
J.Mol.Biol., 347, 2005
4EMF
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BU of 4emf by Molmil
Crystal structure of the complex of type I Ribosome inactivating protein in complex with 7n-methyl-8-hydroguanosine-5-p-diphosphate at 1.77 A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, GLYCEROL, ...
Authors:Yamini, S, Kushwaha, G.S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2012-04-12
Release date:2012-05-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:First structural evidence of sequestration of mRNA cap structures by type 1 ribosome inactivating protein from Momordica balsamina.
Proteins, 81, 2013
4EMR
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BU of 4emr by Molmil
Crystal Structure determination of type1 ribosome inactivating protein complexed with 7-methylguanosine-triphosphate at 1.75A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, rRNA N-glycosidase
Authors:Kumar, M, Kushwaha, G.S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2012-04-12
Release date:2012-05-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:First structural evidence of sequestration of mRNA cap structures by type 1 ribosome inactivating protein from Momordica balsamina.
Proteins, 81, 2013
2KBP
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BU of 2kbp by Molmil
Solution structure of a G-quadruplex of human telomeric RNA
Descriptor: 5'-R(*UP*AP*GP*GP*GP*UP*UP*AP*GP*GP*GP*U)-3'
Authors:Phan, A.T, Martadinata, H.
Deposit date:2008-12-05
Release date:2009-03-24
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of propeller-type parallel-stranded RNA G-quadruplexes, formed by human telomeric RNA sequences in K+ solution.
J.Am.Chem.Soc., 131, 2009
3J06
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BU of 3j06 by Molmil
CryoEM Helical Reconstruction of TMV
Descriptor: 5'-R(P*AP*UP*G)-3', Coat protein
Authors:Ge, P, Zhou, Z.H.
Deposit date:2011-04-26
Release date:2011-06-01
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Hydrogen-bonding networks and RNA bases revealed by cryo electron microscopy suggest a triggering mechanism for calcium switches.
Proc.Natl.Acad.Sci.USA, 108, 2011
1Q67
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BU of 1q67 by Molmil
Crystal structure of Dcp1p
Descriptor: Decapping protein involved in mRNA degradation-Dcp1p
Authors:She, M, Decker, C.J, Liu, Y, Chen, N, Parker, R, Song, H.
Deposit date:2003-08-12
Release date:2004-03-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of Dcp1p and its functional implications in mRNA decapping
Nat.Struct.Mol.Biol., 11, 2004
8C5C
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BU of 8c5c by Molmil
microtubule decorated with tubulin oligomers in presence of APC C-terminal domain. (here only map corresponding to the 13-pf microtubule is represented)
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Serre, L, Arnal, I.
Deposit date:2023-01-06
Release date:2023-01-25
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:The mitotic role of adenomatous polyposis coli requires its bilateral interaction with tubulin and microtubules.
J.Cell.Sci., 136, 2023
1O1W
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BU of 1o1w by Molmil
SOLUTION STRUCTURE OF THE RNASE H DOMAIN OF THE HIV-1 REVERSE TRANSCRIPTASE IN THE PRESENCE OF MAGNESIUM
Descriptor: RIBONUCLEASE H
Authors:Pari, K, Mueller, G.A, Derose, E.F, Kirby, T.W, London, R.E.
Deposit date:2003-02-12
Release date:2003-02-18
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution Structure of the Rnase H Domain of the HIV-1 Reverse Transcriptase in the Presence of Magnesium
Biochemistry, 42, 2003
5H7E
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BU of 5h7e by Molmil
Crystal Structure of native drCPDase
Descriptor: GLYCEROL, RNA 2',3'-cyclic phosphodiesterase, SULFATE ION
Authors:Han, W, Hua, Y, Zhao, Y.
Deposit date:2016-11-18
Release date:2017-09-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the RNA 2',3'-cyclic phosphodiesterase from Deinococcus radiodurans
Acta Crystallogr F Struct Biol Commun, 73, 2017
1UTS
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BU of 1uts by Molmil
Designed HIV-1 TAR Binding Ligand
Descriptor: N-[2-(3-AMINOPROPOXY)-5-(1H-INDOL-5-YL)BENZYL]-N-(2-PIPERAZIN-1-YLETHYL)AMINE, RNA (5'-(*GP*GP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP *CP*CP*UP*GP*GP*GP*AP*GP*CP*UP*CP*UP*CP*UP*GP*CP*C) -3')
Authors:Davis, B, Murchie, A.I.H, Aboul-Ela, F, Karn, J.
Deposit date:2003-12-10
Release date:2004-02-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure-based drug design targeting an inactive RNA conformation: exploiting the flexibility of HIV-1 TAR RNA.
J.Mol.Biol., 336, 2004
316D
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BU of 316d by Molmil
Selectivity of F8-actinomycin D for RNA:DNA hybrids and its anti-leukemia activity
Descriptor: 8-FLUORO-ACTINOMYCIN D, DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*C)-3')
Authors:Takusagawa, F, Takusagawa, K.T, Carlson, R.G, Weaver, R.F.
Deposit date:1997-03-05
Release date:1997-11-05
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Selectivity of F8-Actinomycin D for RNA:DNA Hybrids and its Anti-Leukemia Activity.
Bioorg.Med.Chem., 5, 1997
5BXY
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BU of 5bxy by Molmil
Crystal structure of RNA methyltransferase from Salinibacter ruber in complex with S-Adenosyl-L-homocysteine
Descriptor: CHLORIDE ION, MAGNESIUM ION, RNA methyltransferase, ...
Authors:Handing, K.B, LaRowe, C, Shabalin, I.G, Stead, M, Hillerich, B.S, Ahmed, M, Bonanno, J, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2015-06-09
Release date:2015-07-01
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of RNA methylase family protein from Salinibacterruber in complex with S-Adenosyl-L-homocysteine.
to be published
5FSG
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BU of 5fsg by Molmil
Structure of the hantavirus nucleoprotein provides insights into the mechanism of RNA encapsidation and a template for drug design
Descriptor: MALTOSE-BINDING PERIPLASMIC PROTEIN, HANTAVIRUS NUCLEOPROTEIN, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Olal, D, Daumke, O.
Deposit date:2016-01-05
Release date:2016-04-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.209 Å)
Cite:Structure of the Hantavirus Nucleoprotein Provides Insights Into the Mechanism of RNA Encapsidation.
Cell Rep., 14, 2016
7OUO
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BU of 7ouo by Molmil
Crystal structure of RNA duplex [UCGUGCGA]2 in complex with Ba2+ cation
Descriptor: BARIUM ION, RNA (5'-R(*UP*CP*GP*UP*GP*CP*GP*A)-3')
Authors:Ruszkowski, M, Mao, S, Zheng, Y.Y, Ruszkowska, A, Sheng, J.
Deposit date:2021-06-12
Release date:2022-03-30
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.212 Å)
Cite:Structural Insights Into the 5'UG/3'GU Wobble Tandem in Complex With Ba 2+ Cation.
Front Mol Biosci, 8, 2021
5D6G
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BU of 5d6g by Molmil
CRYSTAL STRUCTURE OF FRAGMENT OF RIBOSOMAL PROTEIN P0 IN COMPLEX WITH 74NT 23S RNA FROM METHANOCOCCUS JANNASCHII
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L10, MAGNESIUM ION
Authors:Gabdulkhakov, A.G, Mitroshin, I.V, Garber, M.B.
Deposit date:2015-08-12
Release date:2016-09-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:CRYSTAL STRUCTURE OF FRAGMENT OF RIBOSOMAL PROTEIN P0 IN COMPLEX WITH 74NT 23S RNA FROM METHANOCOCCUS JANNASCHII
To Be Published
5L00
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BU of 5l00 by Molmil
Self-complimentary RNA 15mer binding with GMP monomers
Descriptor: GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*G)-3')
Authors:Zhang, W, Tam, C.P, Szostak, J.W.
Deposit date:2016-07-26
Release date:2016-12-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Unusual Base-Pairing Interactions in Monomer-Template Complexes.
ACS Cent Sci, 2, 2016
1LB2
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BU of 1lb2 by Molmil
Structure of the E. coli alpha C-terminal domain of RNA polymerase in complex with CAP and DNA
Descriptor: 5'-D(*CP*TP*AP*GP*AP*TP*CP*AP*CP*AP*TP*TP*TP*TP*AP*GP*GP*AP*AP*AP*AP*AP*AP*G)-3', 5'-D(*CP*TP*TP*TP*TP*TP*TP*CP*CP*TP*AP*AP*AP*AP*TP*GP*TP*GP*AP*T)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ...
Authors:Benoff, B, Yang, H, Lawson, C.L, Parkinson, G, Liu, J, Blatter, E, Ebright, Y.W, Berman, H.M, Ebright, R.H.
Deposit date:2002-04-01
Release date:2002-09-06
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis of transcription activation: the CAP-alpha CTD-DNA complex.
Science, 297, 2002
6ZXW
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BU of 6zxw by Molmil
Structure of Archaeoglobus fulgidus Trm11-Trm112 m2G10 tRNA methyltransferase complex bound to sinefungin
Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, SINEFUNGIN, ...
Authors:Graille, M, Wang, C.
Deposit date:2020-07-30
Release date:2020-09-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Functional and structural characterization of the Trm11-Trm112 m2G10 tRNA methyltransferase complex
Nucleic Acids Res., 2020
4DIN
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BU of 4din by Molmil
Novel Localization and Quaternary Structure of the PKA RI beta Holoenzyme
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ...
Authors:Ilouz, R, Bubis, J, Wu, J, Yim, Y.Y, Deal, M.S, Kornev, A.P, Ma, Y, Blumenthal, D.K, Taylor, S.S.
Deposit date:2012-01-31
Release date:2012-07-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Localization and quaternary structure of the PKA RI Beta holoenzyme
Proc.Natl.Acad.Sci.USA, 109, 2012

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