Crystal Structure determination of type1 ribosome inactivating protein complexed with 7-methylguanosine-triphosphate at 1.75A

Summary for 4EMR

DescriptorrRNA N-glycosidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
Functional Keywords7-mgtp, rip complex, hydrolase
Biological sourceMomordica balsamina (Bitter gourd)
Total number of polymer chains1
Total molecular weight28056.37
Kumar, M.,Kushwaha, G.S.,Sinha, M.,Kaur, P.,Sharma, S.,Singh, T.P. (deposition date: 2012-04-12, release date: 2012-05-02, Last modification date: 2020-07-29)
Primary citation
Kushwaha, G.S.,Yamini, S.,Kumar, M.,Sinha, M.,Kaur, P.,Sharma, S.,Singh, T.P.
First structural evidence of sequestration of mRNA cap structures by type 1 ribosome inactivating protein from Momordica balsamina.
Proteins, 81:896-905, 2013
PubMed: 23280611 (PDB entries with the same primary citation)
DOI: 10.1002/prot.24248
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2475 0.4% 1.4% 2.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-09-16