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2VGK
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BU of 2vgk by Molmil
Crystal structure of Actinomadura R39 DD-peptidase complexed with a peptidoglycan-mimetic cephalosporin
Descriptor: (2R)-2-AMINO-7-{[(1R)-1-CARBOXYETHYL]AMINO}-7-OXOHEPTANOIC ACID, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, ...
Authors:Sauvage, E, kerff, F, Herman, R, Charlier, P.
Deposit date:2007-11-14
Release date:2008-11-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structures of Complexes of Bacterial Dd-Peptidases with Peptidoglycan-Mimetic Ligands: The Substrate Specificity Puzzle.
J.Mol.Biol., 381, 2008
2VGJ
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BU of 2vgj by Molmil
Crystal structure of Actinomadura R39 DD-peptidase complexed with a peptidoglycan-mimetic cephalosporin
Descriptor: CEPHALOSPORIN, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, ...
Authors:Sauvage, E, kerff, F, Herman, R, Charlier, P.
Deposit date:2007-11-14
Release date:2008-11-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of Complexes of Bacterial Dd-Peptidases with Peptidoglycan-Mimetic Ligands: The Substrate Specificity Puzzle.
J.Mol.Biol., 381, 2008
3XIM
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BU of 3xim by Molmil
ARGININE RESIDUES AS STABILIZING ELEMENTS IN PROTEINS
Descriptor: COBALT (II) ION, D-XYLOSE ISOMERASE, sorbitol
Authors:Mrabet, N.T, Van Denbroek, A, Van Den Brande, I, Stanssens, P, Laroche, Y, Lambeir, A.-M, Matthyssens, G, Jenkins, J, Chiadmi, M, Vantilbeurgh, H, Rey, F, Janin, J, Quax, W.J, Lasters, I, Demaeyer, M, Wodak, S.J.
Deposit date:1991-05-29
Release date:1993-04-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Arginine residues as stabilizing elements in proteins.
Biochemistry, 31, 1992
5WNM
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BU of 5wnm by Molmil
Crystal structure of murine receptor-interacting protein 4 (Ripk4) D143N bound to tozasertib (VX-680)
Descriptor: CHLORIDE ION, CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE, Receptor-interacting serine/threonine-protein kinase 4
Authors:Huang, C.S, Hymowitz, S.G.
Deposit date:2017-08-01
Release date:2018-05-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity.
Structure, 26, 2018
5WNJ
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BU of 5wnj by Molmil
Crystal structure of murine receptor-interacting protein kinase 4 (Ripk4) D143N in complex with lestaurtinib
Descriptor: CHLORIDE ION, Lestaurtinib, Receptor-interacting serine/threonine-protein kinase 4
Authors:Huang, C.S, Hymowitz, S.G.
Deposit date:2017-08-01
Release date:2018-05-09
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity.
Structure, 26, 2018
5WNI
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BU of 5wni by Molmil
Crystal structure of murine receptor-interacting protein kinase 4 (Ripk4) D143N in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Huang, C.S, Hymowitz, S.G.
Deposit date:2017-08-01
Release date:2018-05-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity.
Structure, 26, 2018
5WNL
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BU of 5wnl by Molmil
Crystal structure of murine receptor-interacting protein 4 (Ripk4) D143N bound to staurosporine
Descriptor: CHLORIDE ION, Receptor-interacting serine/threonine-protein kinase 4, STAUROSPORINE
Authors:Huang, C.S, Hymowitz, S.G.
Deposit date:2017-08-01
Release date:2018-05-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity.
Structure, 26, 2018
5WNK
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BU of 5wnk by Molmil
Crystal structure of murine receptor-interacting protein 4 (Ripk4) D143N bound to TG100-115
Descriptor: 3,3'-(2,4-diaminopteridine-6,7-diyl)diphenol, CHLORIDE ION, Receptor-interacting serine/threonine-protein kinase 4
Authors:Huang, C.S, Hymowitz, S.G.
Deposit date:2017-08-01
Release date:2018-05-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity.
Structure, 26, 2018
1THM
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BU of 1thm by Molmil
CRYSTAL STRUCTURE OF THERMITASE AT 1.4 ANGSTROMS RESOLUTION
Descriptor: CALCIUM ION, SODIUM ION, SULFATE ION, ...
Authors:Teplyakov, A.V, Kuranova, I.P, Harutyunyan, E.H.
Deposit date:1992-02-24
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Crystal structure of thermitase at 1.4 A resolution.
J.Mol.Biol., 214, 1990
7LJY
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BU of 7ljy by Molmil
Cryo-EM structure of the B dENE construct complexed with a 28-mer poly(A)
Descriptor: B dENE construct, poly(A)
Authors:Torabi, S, Chen, Y, Zhang, K, Wang, J, DeGregorio, S, Vaidya, A, Su, Z, Pabit, S, Chiu, W, Pollack, L, Steitz, J.
Deposit date:2021-02-01
Release date:2021-04-14
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Structural analyses of an RNA stability element interacting with poly(A).
Proc.Natl.Acad.Sci.USA, 118, 2021
6J0H
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BU of 6j0h by Molmil
Crystal structure of Actinomycin D- d(TTGGCGAA) complex
Descriptor: Actinomycin D, DNA (5'-D(P*TP*TP*GP*GP*CP*GP*AP*A)-3'), SODIUM ION
Authors:Satange, R.B, Hou, M.H.
Deposit date:2018-12-24
Release date:2019-07-24
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Polymorphic G:G mismatches act as hotspots for inducing right-handed Z DNA by DNA intercalation.
Nucleic Acids Res., 47, 2019
6R5F
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BU of 6r5f by Molmil
Crystal structure of RIP1 kinase in complex with DHP77
Descriptor: Receptor-interacting serine/threonine-protein kinase 1, [(5~{S})-5-[3,5-bis(fluoranyl)phenyl]pyrazolidin-1-yl]-[1-(5-methyl-1,3,4-oxadiazol-2-yl)piperidin-4-yl]methanone
Authors:Thorpe, J.H, Campobasso, N, Harris, P.A.
Deposit date:2019-03-25
Release date:2019-05-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase.
J.Med.Chem., 62, 2019
4QAM
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BU of 4qam by Molmil
Crystal Structure of the RPGR RCC1-like domain in complex with the RPGR-interacting domain of RPGRIP1
Descriptor: GLYCEROL, MAGNESIUM ION, X-linked retinitis pigmentosa GTPase regulator, ...
Authors:Remans, K, Buerger, M, Vetter, I.R, Wittinghofer, A.
Deposit date:2014-05-05
Release date:2014-07-30
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:C2 domains as protein-protein interaction modules in the ciliary transition zone.
Cell Rep, 8, 2014
6JC7
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BU of 6jc7 by Molmil
Crystal structure of aminotransferase CrmG from Actinoalloteichus sp. WH1-2216-6 in complex with amino donor L-Ala
Descriptor: (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-alanine, ACETIC ACID, CrmG, ...
Authors:Xu, J, Su, K, Liu, J.
Deposit date:2019-01-28
Release date:2020-02-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural studies reveal flexible roof of active site responsible for omega-transaminase CrmG overcoming by-product inhibition.
Commun Biol, 3, 2020
6JC9
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BU of 6jc9 by Molmil
Crystal structure of aminotransferase CrmG from Actinoalloteichus sp. WH1-2216-6 in complex with amino donor L-Gln
Descriptor: ACETIC ACID, CrmG, GLUTAMINE, ...
Authors:Xu, J, Liu, J.
Deposit date:2019-01-28
Release date:2020-02-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural studies reveal flexible roof of active site responsible for omega-transaminase CrmG overcoming by-product inhibition.
Commun Biol, 3, 2020
4TSO
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BU of 4tso by Molmil
Crystal structure of FraC with DHPC bound (crystal form I)
Descriptor: 1,2-dihexanoyl-sn-glycero-3-phosphocholine, Fragaceatoxin C, PHOSPHATE ION, ...
Authors:Caaveiro, J.M.M, Tanaka, K, Tsumoto, K.
Deposit date:2014-06-19
Release date:2015-03-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
4TSP
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BU of 4tsp by Molmil
Crystal structure of FraC with DHPC bound (crystal form II)
Descriptor: 1,2-dihexanoyl-sn-glycero-3-phosphocholine, Fragaceatoxin C, PHOSPHATE ION, ...
Authors:Caaveiro, J.M.M, Tanaka, K, Tsumoto, K.
Deposit date:2014-06-19
Release date:2015-03-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
4TSY
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BU of 4tsy by Molmil
Crystal structure of FraC with lipids
Descriptor: 2-[[(E,2S,3R)-2-(hexanoylamino)-3-oxidanyl-dec-4-enoxy]-oxidanyl-phosphoryl]oxyethyl-trimethyl-azanium, Fragaceatoxin C, HEPTANE-1,2,3-TRIOL, ...
Authors:Caaveiro, J.M.M, Tanaka, K, Tsumoto, K.
Deposit date:2014-06-19
Release date:2015-03-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
4TSL
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BU of 4tsl by Molmil
Crystal structure of FraC with POC bound (crystal form I)
Descriptor: ACETATE ION, FORMIC ACID, Fragaceatoxin C, ...
Authors:Caaveiro, J.M.M, Tanaka, K, Tsumoto, K.
Deposit date:2014-06-19
Release date:2015-03-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
4TSN
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BU of 4tsn by Molmil
Crystal structure of FraC with POC bound (crystal form II)
Descriptor: ACETATE ION, Fragaceatoxin C, GLYCEROL, ...
Authors:Caaveiro, J.M.M, Tanaka, K, Tsumoto, K.
Deposit date:2014-06-19
Release date:2015-03-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
4TSQ
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BU of 4tsq by Molmil
Crystal structure of FraC with DHPC bound (crystal form III)
Descriptor: 1,2-dihexanoyl-sn-glycero-3-phosphocholine, CHLORIDE ION, Fragaceatoxin C, ...
Authors:Caaveiro, J.M.M, Tanaka, K, Tsumoto, K.
Deposit date:2014-06-19
Release date:2015-03-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
4J8D
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BU of 4j8d by Molmil
Middle domain of Hsc70-interacting protein, crystal form II
Descriptor: Hsc70-interacting protein
Authors:Li, Z, Bracher, A.
Deposit date:2013-02-14
Release date:2013-07-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure and function of Hip, an attenuator of the Hsp70 chaperone cycle.
Nat.Struct.Mol.Biol., 20, 2013
3HO4
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BU of 3ho4 by Molmil
Crystal structure of Hedgehog-interacting protein (HHIP)
Descriptor: Hedgehog-interacting protein
Authors:Hymowitz, S.G, Bosanac, I.
Deposit date:2009-06-01
Release date:2009-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling.
Nat.Struct.Mol.Biol., 16, 2009
3HO3
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BU of 3ho3 by Molmil
Crystal structure of Hedgehog-interacting protein (HHIP)
Descriptor: Hedgehog-interacting protein
Authors:Bosanac, I, Hymowitz, S.G.
Deposit date:2009-06-01
Release date:2009-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling.
Nat.Struct.Mol.Biol., 16, 2009
8P5W
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BU of 8p5w by Molmil
Single particle cryo-EM structure of homohexameric 2-oxoglutarate dehydrogenase OdhA from Corynebacterium glutamicum following reaction with the 2-oxoglutarate analogue succinyl phosphonate
Descriptor: (4~{S})-4-[(2~{R})-3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-5-[2-[oxidanyl(phosphonooxy)phosphoryl]oxyethyl]-2~{H}-1,3-thiazol-2-yl]-4-oxidanyl-4-phosphono-butanoic acid, 2-oxoglutarate dehydrogenase E1/E2 component, ACETYL COENZYME *A, ...
Authors:Yang, L, Mechaly, A.M, Bellinzoni, M.
Deposit date:2023-05-24
Release date:2023-08-16
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (2.26 Å)
Cite:High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase.
Nat Commun, 14, 2023

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