4CEJ
 
 | | Crystal structure of AddAB-DNA-ADPNP complex at 3 Angstrom resolution | | Descriptor: | ATP-DEPENDENT HELICASE/DEOXYRIBONUCLEASE SUBUNIT B, ATP-DEPENDENT HELICASE/NUCLEASE SUBUNIT A, DNA, ... | | Authors: | Krajewski, W.W, Wilkinson, M, Fu, X, Cronin, N.B, Wigley, D. | | Deposit date: | 2013-11-11 | | Release date: | 2014-03-12 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural Basis for Translocation by Addab Helicase-Nuclease and its Arrest at Chi Sites.
Nature, 508, 2014
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2L4M
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2F4Q
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7QW8
 | | Adenine-specific DNA methyltransferase M.BseCI | | Descriptor: | Modification methylase BseCI | | Authors: | Mitsikas, D.A, Kouyianou, K, Kotsifaki, D, Providaki, M, Bouriotis, V, Glykos, N.M, Kokkinidis, M. | | Deposit date: | 2022-01-24 | | Release date: | 2023-01-25 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of M.BseCI DNA methyltransferase from Geobacillus stearothermophilus.
To Be Published
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1I3W
 | | ACTINOMYCIN D BINDING TO CGATCGATCG | | Descriptor: | 5'-D(*C*GP*AP*TP*CP*GP*AP*(BRU)P*CP*GP)-3', ACTINOMYCIN D | | Authors: | Robinson, H, Gao, Y.-G, Yang, X.-L, Sanishvili, R, Joachimiak, A, Wang, A.H.-J. | | Deposit date: | 2001-02-17 | | Release date: | 2001-05-21 | | Last modified: | 2024-07-10 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystallographic Analysis of a Novel Complex of Actinomycin D Bound to the DNA Decamer Cgatcgatcg.
Biochemistry, 40, 2001
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6RY3
 | | Structure of the WUS homeodomain | | Descriptor: | ACETYL GROUP, Protein WUSCHEL, SULFATE ION | | Authors: | Sloan, J.J, Wild, K, Sinning, I. | | Deposit date: | 2019-06-10 | | Release date: | 2020-04-29 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.374 Å) | | Cite: | Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL.
Nat Commun, 11, 2020
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1IQT
 | | Solution structure of the C-terminal RNA-binding domain of heterogeneous nuclear ribonucleoprotein D0 (AUF1) | | Descriptor: | heterogeneous nuclear ribonucleoprotein D0 | | Authors: | Katahira, M, Miyanoiri, Y, Enokizono, Y, Matsuda, G, Nagata, T, Ishikawa, F, Uesugi, S. | | Deposit date: | 2001-08-01 | | Release date: | 2002-08-07 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Structure of the C-terminal RNA-binding domain of hnRNP D0 (AUF1), its interactions with RNA and DNA, and change in backbone dynamics upon complex formation with DNA.
J.Mol.Biol., 311, 2001
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6PLC
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6P81
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5VAJ
 | | BhRNase H - amide-RNA/DNA complex | | Descriptor: | ACETATE ION, DNA (5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3'), GLYCEROL, ... | | Authors: | Pallan, P.S, Egli, M. | | Deposit date: | 2017-03-27 | | Release date: | 2017-09-13 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Amide linkages mimic phosphates in RNA interactions with proteins and are well tolerated in the guide strand of short interfering RNAs.
Nucleic Acids Res., 45, 2017
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8W35
 | | Aca2 from Pectobacterium phage ZF40 bound to RNA | | Descriptor: | Anti-CRISPR associated (Aca) protein, Aca2, IR2 and IR-RBS RNA | | Authors: | Wilkinson, M.E, Birkholz, N, Kimanius, D, Fineran, P.C. | | Deposit date: | 2024-02-21 | | Release date: | 2024-07-24 | | Last modified: | 2024-08-14 | | Method: | ELECTRON MICROSCOPY (2.61 Å) | | Cite: | Phage anti-CRISPR control by an RNA- and DNA-binding helix-turn-helix protein.
Nature, 631, 2024
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6YN1
 | | Crystal structure of histone chaperone APLF acidic domain bound to the histone H2A-H2B-H3-H4 octamer | | Descriptor: | Aprataxin and PNK-like factor, CHLORIDE ION, GLYCEROL, ... | | Authors: | Corbeski, I, Guo, X, Van Ingen, H, Sixma, T.K. | | Deposit date: | 2020-04-10 | | Release date: | 2021-11-17 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLF.
Sci Adv, 8, 2022
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2H7G
 | | Structure of variola topoisomerase non-covalently bound to DNA | | Descriptor: | 5'-D(*TP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*AP*CP*A)-3', 5'-D(*TP*TP*GP*TP*CP*GP*CP*CP*CP*TP*TP*A)-3', DNA topoisomerase 1 | | Authors: | Perry, K, Hwang, Y, Bushman, F.D, Van Duyne, G.D. | | Deposit date: | 2006-06-02 | | Release date: | 2006-08-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for specificity in the poxvirus topoisomerase.
Mol.Cell, 23, 2006
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8F27
 | | Mirror-image DNA containing 2'-OMe-L-uridine residue | | Descriptor: | Mirror-image DNA (5'-D(*(0DG)P*(0MU)P*(0DG)P*(0DT)P*(0DA)P*(0DC)P*(0DA)P*(0DC))-3'), SULFATE ION | | Authors: | Zhang, W, Dantsu, Y. | | Deposit date: | 2022-11-07 | | Release date: | 2023-04-12 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Derivatization of Mirror-Image l-Nucleic Acids with 2'-OMe Modification for Thermal and Structural Stabilization.
Chembiochem, 24, 2023
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4RXJ
 | | crystal structure of WHSC1L1-PWWP2 | | Descriptor: | Histone-lysine N-methyltransferase NSD3, UNKNOWN ATOM OR ION | | Authors: | Qin, S, Tempel, W, Dong, A, Li, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2014-12-11 | | Release date: | 2015-01-28 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Histone and DNA binding ability studies of the NSD subfamily of PWWP domains.
Biochem.Biophys.Res.Commun., 569, 2021
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7TAW
 | | Cryo-EM structure of the Csy-AcrIF24-promoter DNA dimer | | Descriptor: | AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR type I-F/YPEST-associated protein Csy3, ... | | Authors: | Mukherjee, I.A, Chang, L. | | Deposit date: | 2021-12-21 | | Release date: | 2022-09-21 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural basis of AcrIF24 as an anti-CRISPR protein and transcriptional suppressor.
Nat.Chem.Biol., 18, 2022
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7TAX
 | | Cryo-EM structure of the Csy-AcrIF24-promoter DNA complex | | Descriptor: | AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR type I-F/YPEST-associated protein Csy3, ... | | Authors: | Mukherjee, I.A, Chang, L. | | Deposit date: | 2021-12-21 | | Release date: | 2022-09-21 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural basis of AcrIF24 as an anti-CRISPR protein and transcriptional suppressor.
Nat.Chem.Biol., 18, 2022
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1DNO
 | | A-DNA/RNA DODECAMER R(GCG)D(TATACGC) MG BINDING SITES | | Descriptor: | DNA/RNA (5'-R(*GP*CP*GP)-D(*TP*AP*TP*AP*CP*GP*C)-3'), MAGNESIUM ION | | Authors: | Robinson, H, Gao, Y.-G, Sanishvili, R, Joachimiak, A, Wang, A.H.-J. | | Deposit date: | 1999-12-16 | | Release date: | 2000-04-10 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Hexahydrated magnesium ions bind in the deep major groove and at the outer mouth of A-form nucleic acid duplexes.
Nucleic Acids Res., 28, 2000
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8Q7I
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4ATK
 | | MITF:E-box complex | | Descriptor: | 5'-D(*AP*GP*TP*AP*GP*CP*AP*CP*GP*TP*GP*CP*TP*AP*CP*T)-3', MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR | | Authors: | Pogenberg, V, Deineko, V, Wilmanns, M. | | Deposit date: | 2012-05-08 | | Release date: | 2012-12-12 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Restricted Leucine Zipper Dimerization and Specificity of DNA Recognition of the Melanocyte Master Regulator Mitf
Genes Dev., 26, 2012
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2B0E
 | | EcoRV Restriction Endonuclease/GAAUTC/Ca2+ | | Descriptor: | 5'-D(*AP*AP*AP*GP*AP*AP*(DU)P*TP*CP*TP*T)-3', CALCIUM ION, Type II restriction enzyme EcoRV | | Authors: | Hiller, D.A, Rodriguez, A.M, Perona, J.J. | | Deposit date: | 2005-09-13 | | Release date: | 2005-09-27 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Non-cognate Enzyme-DNA Complex: Structural and Kinetic Analysis of EcoRV Endonuclease Bound to the EcoRI Recognition Site GAATTC
J.Mol.Biol., 354, 2005
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3NNQ
 | | Crystal Structure of the N-terminal domain of Moloney murine leukemia virus integrase, Northeast Structural Genomics Consortium Target OR3 | | Descriptor: | ACETATE ION, N-terminal domain of Moloney murine leukemia virus integrase, ZINC ION | | Authors: | Guan, R, Xiao, R, Acton, T, Jiang, M, Roth, M, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2010-06-24 | | Release date: | 2010-07-14 | | Last modified: | 2023-07-26 | | Method: | X-RAY DIFFRACTION (2.693 Å) | | Cite: | X-ray crystal structure of the N-terminal region of Moloney murine leukemia virus integrase and its implications for viral DNA recognition.
Proteins, 85, 2017
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2B0D
 | | EcoRV Restriction Endonuclease/GAATTC/Ca2+ | | Descriptor: | 5'-D(*AP*AP*AP*GP*AP*AP*TP*TP*CP*TP*T)-3', CALCIUM ION, Type II restriction enzyme EcoRV | | Authors: | Hiller, D.A, Rodriguez, A.M, Perona, J.J. | | Deposit date: | 2005-09-13 | | Release date: | 2005-09-27 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Non-cognate Enzyme-DNA Complex: Structural and Kinetic Analysis of EcoRV Endonuclease Bound to the EcoRI Recognition Site GAATTC
J.Mol.Biol., 354, 2005
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7LCC
 | | Helitron transposase bound to LTS | | Descriptor: | Helraiser K1068Q, LTS, ZINC ION | | Authors: | Kosek, D, Dyda, F. | | Deposit date: | 2021-01-10 | | Release date: | 2021-08-25 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.66 Å) | | Cite: | The large bat Helitron DNA transposase forms a compact monomeric assembly that buries and protects its covalently bound 5'-transposon end.
Mol.Cell, 81, 2021
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2H7F
 | | Structure of variola topoisomerase covalently bound to DNA | | Descriptor: | 5'-D(*TP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*AP*CP*A)-3', 5'-D(*TP*TP*GP*TP*CP*GP*CP*CP*CP*TP*T)-3', DNA topoisomerase 1 | | Authors: | Perry, K, Hwang, Y, Bushman, F.D, Van Duyne, G.D. | | Deposit date: | 2006-06-02 | | Release date: | 2006-08-15 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis for specificity in the poxvirus topoisomerase.
Mol.Cell, 23, 2006
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