7UWN
| Structure of the IL-17A-IL-17RA-IL-17RC ternary complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ... | Authors: | Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C. | Deposit date: | 2022-05-03 | Release date: | 2022-07-27 | Last modified: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Organizing structural principles of the IL-17 ligand-receptor axis. Nature, 609, 2022
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7V27
| RBD/XG005 local refinement | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, XG005-VH, ... | Authors: | Zhan, W.Q, Zhang, X, Sun, L, Chen, Z.G. | Deposit date: | 2021-08-07 | Release date: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (4.18 Å) | Cite: | RBD/XG005 local refinement To Be Published
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7UJB
| N-terminal domain deletion variant of Eta | Descriptor: | DEAD/DEAH box RNA helicase | Authors: | Qayyum, M.Z, Murakami, K.S. | Deposit date: | 2022-03-30 | Release date: | 2022-08-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (4.12 Å) | Cite: | The structure and activities of the archaeal transcription termination factor Eta detail vulnerabilities of the transcription elongation complex. Proc.Natl.Acad.Sci.USA, 119, 2022
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1FFS
| CHEY-BINDING DOMAIN OF CHEA IN COMPLEX WITH CHEY FROM CRYSTALS SOAKED IN ACETYL PHOSPHATE | Descriptor: | CHEMOTAXIS PROTEIN CHEA, CHEMOTAXIS PROTEIN CHEY, MANGANESE (II) ION | Authors: | Gouet, P, Chinardet, N, Welch, M, Guillet, V, Birck, C, Mourey, L, Samama, J.-P. | Deposit date: | 2000-07-26 | Release date: | 2001-01-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Further insights into the mechanism of function of the response regulator CheY from crystallographic studies of the CheY--CheA(124--257) complex. Acta Crystallogr.,Sect.D, 57, 2001
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7UPH
| Structure of a ribosome with tethered subunits | Descriptor: | 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | Authors: | Kim, D.S, Watkins, A, Bidstrup, E, Lee, J, Topkar, V.V, Kofman, C, Schwarz, K.J, Liu, Y, Pintilie, G, Roney, E, Das, R, Jewett, M.C. | Deposit date: | 2022-04-15 | Release date: | 2022-08-17 | Last modified: | 2022-08-31 | Method: | ELECTRON MICROSCOPY (4.18 Å) | Cite: | Three-dimensional structure-guided evolution of a ribosome with tethered subunits. Nat.Chem.Biol., 18, 2022
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7UOL
| Endogenous dihydrolipoamide succinyltransferase (E2) core of 2-oxoglutarate dehydrogenase complex from bovine kidney | Descriptor: | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | Authors: | Liu, S, Xia, X, Zhen, J, Li, Z.H, Zhou, Z.H. | Deposit date: | 2022-04-13 | Release date: | 2022-11-30 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structures and comparison of endogenous 2-oxoglutarate and pyruvate dehydrogenase complexes from bovine kidney. Cell Discov, 8, 2022
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7UOM
| Endogenous dihydrolipoamide acetyltransferase (E2) core of pyruvate dehydrogenase complex from bovine kidney | Descriptor: | Acetyltransferase component of pyruvate dehydrogenase complex | Authors: | Liu, S, Xia, X, Zhen, J, Li, Z.H, Zhou, Z.H. | Deposit date: | 2022-04-13 | Release date: | 2022-11-30 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structures and comparison of endogenous 2-oxoglutarate and pyruvate dehydrogenase complexes from bovine kidney. Cell Discov, 8, 2022
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2OII
| Structure of EMILIN-1 C1q-like domain | Descriptor: | EMILIN-1 | Authors: | Verdone, G, Colebrooke, S.A, Corazza, A, Cicero, D.O, Eliseo, T, Viglino, P, Campbell, I.D, Colombatti, A, Esposito, G. | Deposit date: | 2007-01-11 | Release date: | 2008-01-22 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | The solution structure of the C-terminal domain of EMILIN-1 To be Published
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7UJ4
| Inhibition of Human Menin by SNDX-5613 | Descriptor: | 2-({4-[7-({(1r,4r)-4-[(ethanesulfonyl)amino]cyclohexyl}methyl)-2,7-diazaspiro[3.5]nonan-2-yl]pyrimidin-5-yl}oxy)-N-ethyl-5-fluoro-N-(propan-2-yl)benzamide, Isoform 2 of Menin, MAGNESIUM ION | Authors: | McKeever, B.M, Kulkarni, S, McGeehan, G.M. | Deposit date: | 2022-03-30 | Release date: | 2022-12-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | MEN1 mutations mediate clinical resistance to menin inhibition. Nature, 615, 2023
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7UJX
| Structure of cAMP-dependent protein kinase using a MD-MX procedure, produced using 2.4 Angstrom data | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Wych, D.C, Aoto, P.C, Wall, M.E. | Deposit date: | 2022-03-31 | Release date: | 2022-12-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular-dynamics simulation methods for macromolecular crystallography. Acta Crystallogr D Struct Biol, 79, 2023
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7UKJ
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1Y10
| Mycobacterial adenylyl cyclase Rv1264, holoenzyme, inhibited state | Descriptor: | CALCIUM ION, Hypothetical protein Rv1264/MT1302, PENTAETHYLENE GLYCOL | Authors: | Tews, I, Findeisen, F, Sinning, I, Schultz, A, Schultz, J.E, Linder, J.U. | Deposit date: | 2004-11-16 | Release date: | 2005-05-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The structure of a pH-sensing mycobacterial adenylyl cyclase holoenzyme Science, 308, 2005
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7V0G
| Structure of cAMP-dependent protein kinase using a MD-MX procedure, produced using 1.63 Angstrom data | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Wych, D.C, Aoto, P.C, Wall, M.E. | Deposit date: | 2022-05-10 | Release date: | 2022-12-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Molecular-dynamics simulation methods for macromolecular crystallography. Acta Crystallogr D Struct Biol, 79, 2023
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7UV8
| Rad6-Bre1 Complex | Descriptor: | E3 ubiquitin-protein ligase BRE1, Ubiquitin-conjugating enzyme E2 2 | Authors: | Shukla, P.K, Chandrasekharan, M.B. | Deposit date: | 2022-04-29 | Release date: | 2023-01-11 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure and functional determinants of Rad6-Bre1 subunits in the histone H2B ubiquitin-conjugating complex. Nucleic Acids Res., 51, 2023
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7UVC
| Rad6(P43L)-Bre1 Complex | Descriptor: | E3 ubiquitin-protein ligase BRE1, Ubiquitin-conjugating enzyme E2 2 | Authors: | Shukla, P.K, Chandrasekharan, M.B. | Deposit date: | 2022-04-29 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structure and functional determinants of Rad6-Bre1 subunits in the histone H2B ubiquitin-conjugating complex. Nucleic Acids Res., 51, 2023
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7UD6
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7UUR
| The 1.67 Angstrom CryoEM structure of the [NiFe]-hydrogenase Huc from Mycobacterium smegmatis - catalytic dimer (Huc2S2L) | Descriptor: | CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, HYDROXIDE ION, ... | Authors: | Grinter, R, Venugopal, H, Kropp, A, Greening, C. | Deposit date: | 2022-04-28 | Release date: | 2023-01-04 | Last modified: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (1.67 Å) | Cite: | Structural basis for bacterial energy extraction from atmospheric hydrogen. Nature, 615, 2023
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7UUS
| The CryoEM structure of the [NiFe]-hydrogenase Huc from Mycobacterium smegmatis - Full complex focused refinement of stalk | Descriptor: | CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, Hydrogenase-2, ... | Authors: | Grinter, R, Venugopal, H, Kropp, A, Greening, C. | Deposit date: | 2022-04-28 | Release date: | 2023-01-04 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | Structural basis for bacterial energy extraction from atmospheric hydrogen. Nature, 615, 2023
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7UTD
| The 2.19-angstrom CryoEM structure of the [NiFe]-hydrogenase Huc from Mycobacterium smegmatis - Complex minus stalk | Descriptor: | CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, Hydrogenase-2, ... | Authors: | Grinter, R, Venugopal, H, Kropp, A, Greening, C. | Deposit date: | 2022-04-26 | Release date: | 2023-01-04 | Last modified: | 2023-04-05 | Method: | ELECTRON MICROSCOPY (2.19 Å) | Cite: | Structural basis for bacterial energy extraction from atmospheric hydrogen. Nature, 615, 2023
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7UDQ
| Crystal structure of COQ8A-CA157 inhibitor complex in space group P1 | Descriptor: | 4-[(3,4,5-trimethoxyphenyl)amino]quinoline-7-carbonitrile, Atypical kinase COQ8A, mitochondrial, ... | Authors: | Bingman, C.A, Murray, N, Smith, R.W, Pagliarini, D.J. | Deposit date: | 2022-03-20 | Release date: | 2023-01-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Small-molecule inhibition of the archetypal UbiB protein COQ8. Nat.Chem.Biol., 19, 2023
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7UDP
| Crystal structure of COQ8A-CA157 inhibitor complex in space group C2 | Descriptor: | 4-[(3,4,5-trimethoxyphenyl)amino]quinoline-7-carbonitrile, Atypical kinase COQ8A, mitochondrial | Authors: | Bingman, C.A, Murray, N, Smith, R.W, Pagliarini, D.J. | Deposit date: | 2022-03-20 | Release date: | 2023-01-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Small-molecule inhibition of the archetypal UbiB protein COQ8. Nat.Chem.Biol., 19, 2023
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7UXA
| Human tRNA Splicing Endonuclease Complex bound to pre-tRNA-ARG | Descriptor: | MAGNESIUM ION, RNA (78-MER), tRNA-splicing endonuclease subunit Sen15, ... | Authors: | Stanley, R.E, Hayne, C.K. | Deposit date: | 2022-05-05 | Release date: | 2023-02-08 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex. Nat.Struct.Mol.Biol., 30, 2023
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7UIC
| Mediator-PIC Early (Tail A) | Descriptor: | Mediator of RNA polymerase II transcription subunit 14, Mediator of RNA polymerase II transcription subunit 15, Mediator of RNA polymerase II transcription subunit 16, ... | Authors: | Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K. | Deposit date: | 2022-03-29 | Release date: | 2023-02-15 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis of a transcription pre-initiation complex on a divergent promoter. Mol.Cell, 83, 2023
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7UIL
| Mediator-PIC Early (Tail A/B Dimer) | Descriptor: | Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 14, Mediator of RNA polymerase II transcription subunit 15, ... | Authors: | Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K. | Deposit date: | 2022-03-29 | Release date: | 2023-02-15 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural basis of a transcription pre-initiation complex on a divergent promoter. Mol.Cell, 83, 2023
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7UIF
| Mediator-PIC Early (Core B) | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K. | Deposit date: | 2022-03-29 | Release date: | 2023-02-15 | Last modified: | 2023-03-08 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural basis of a transcription pre-initiation complex on a divergent promoter. Mol.Cell, 83, 2023
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