7UDP
Crystal structure of COQ8A-CA157 inhibitor complex in space group C2
Summary for 7UDP
Entry DOI | 10.2210/pdb7udp/pdb |
Descriptor | Atypical kinase COQ8A, mitochondrial, 4-[(3,4,5-trimethoxyphenyl)amino]quinoline-7-carbonitrile (3 entities in total) |
Functional Keywords | coq biosynthesis, kinase-like, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 45583.32 |
Authors | Bingman, C.A.,Murray, N.,Smith, R.W.,Pagliarini, D.J. (deposition date: 2022-03-20, release date: 2023-01-18, Last modification date: 2023-10-25) |
Primary citation | Murray, N.H.,Asquith, C.R.M.,Fang, Z.,East, M.P.,Ptak, N.,Smith, R.W.,Vasta, J.D.,Zimprich, C.A.,Corona, C.R.,Robers, M.B.,Johnson, G.L.,Bingman, C.A.,Pagliarini, D.J. Small-molecule inhibition of the archetypal UbiB protein COQ8. Nat.Chem.Biol., 19:230-238, 2023 Cited by PubMed: 36302899DOI: 10.1038/s41589-022-01168-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.01 Å) |
Structure validation
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