8HMF
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![BU of 8hmf by Molmil](/molmil-images/mine/8hmf) | head module state 2 of Tetrahymena IFT-A | Descriptor: | Intraflagellar transport protein 122 homolog, Intraflagellar transporter, WD40 repeat protein, ... | Authors: | Ma, Y, Wu, J, Lei, M. | Deposit date: | 2022-12-03 | Release date: | 2023-06-14 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train. Nat Commun, 14, 2023
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8QA4
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![BU of 8qa4 by Molmil](/molmil-images/mine/8qa4) | MTHFR + SAH symmetric dis-inhibited state | Descriptor: | Methylenetetrahydrofolate reductase (NADPH), S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Blomgren, L.K.M, Yue, W.W, Froese, D.S, McCorvie, T.J. | Deposit date: | 2023-08-22 | Release date: | 2023-11-08 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Dynamic inter-domain transformations mediate the allosteric regulation of human 5, 10-methylenetetrahydrofolate reductase. Nat Commun, 15, 2024
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1KLO
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![BU of 1klo by Molmil](/molmil-images/mine/1klo) | |
8D78
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8D79
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![BU of 8d79 by Molmil](/molmil-images/mine/8d79) | Crystal structure of a four-tetrad, parallel, and Na+ stabilized Tetrahymena thermophila telomeric G-quadruplex in complex with N-methyl mesoporphyrin IX | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*T)-3'), N-METHYLMESOPORPHYRIN, ... | Authors: | Chen, E.V, Beseiso, D, Yatsunyk, L.A. | Deposit date: | 2022-06-07 | Release date: | 2023-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Biophysical and structural characterization of telomeric G-quadruplexes from Tetrahymena thermophila in complex with N-Methyl Mesoporphyrin IX To Be Published
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3L93
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![BU of 3l93 by Molmil](/molmil-images/mine/3l93) | Phosphopantetheine adenylyltransferase from Yersinia pestis. | Descriptor: | FORMIC ACID, Phosphopantetheine adenylyltransferase | Authors: | Osipiuk, J, Maltseva, N, Makowska-grzyska, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2010-01-04 | Release date: | 2010-01-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | X-ray crystal structure of phosphopantetheine adenylyltransferase from Yersinia pestis. To be Published
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5XAZ
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5IH7
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3FK6
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![BU of 3fk6 by Molmil](/molmil-images/mine/3fk6) | Crystal structure of TetR triple mutant (H64K, S135L, S138I) | Descriptor: | Tetracycline repressor protein class B from transposon Tn10, Tetracycline repressor protein class D | Authors: | Klieber, M.A, Scholz, O, Lochner, S, Gmeiner, P, Hillen, W, Muller, Y.A. | Deposit date: | 2008-12-16 | Release date: | 2009-10-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural origins for selectivity and specificity in an engineered bacterial repressor-inducer pair. Febs J., 276, 2009
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7NWD
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![BU of 7nwd by Molmil](/molmil-images/mine/7nwd) | Three-quartet c-kit2 G-quadruplex stabilized by a pyrene conjugate | Descriptor: | POTASSIUM ION, c-kit2_py1 | Authors: | Peterkova, K, Durnik, I, Marek, R, Plavec, J, Podbevsek, P. | Deposit date: | 2021-03-16 | Release date: | 2021-08-04 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | c-kit2 G-quadruplex stabilized via a covalent probe: exploring G-quartet asymmetry. Nucleic Acids Res., 49, 2021
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5XAY
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5E3Q
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![BU of 5e3q by Molmil](/molmil-images/mine/5e3q) | Crystal structure of DapD in complex with succinyl-CoA from Corynebacterium glutamicum | Descriptor: | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, SUCCINYL-COENZYME A | Authors: | Sagong, H.-Y, Kim, K.-J. | Deposit date: | 2015-10-03 | Release date: | 2015-11-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure and Biochemical Characterization of Tetrahydrodipicolinate N-Succinyltransferase from Corynebacterium glutamicum. J.Agric.Food Chem., 63, 2015
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3HVL
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![BU of 3hvl by Molmil](/molmil-images/mine/3hvl) | Tethered PXR-LBD/SRC-1p complexed with SR-12813 | Descriptor: | Pregnane X receptor, Linker, Steroid receptor coactivator 1, ... | Authors: | Lesburg, C.A, Wang, W, Prosise, W.W, Chen, J, Taremi, S.S, Le, H.V, Madison, V, Cui, X, Thomas, A, Cheng, K.C. | Deposit date: | 2009-06-16 | Release date: | 2009-08-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Construction and characterization of a fully active PXR/SRC-1 tethered protein with increased stability Protein Eng.Des.Sel., 21, 2008
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6QMG
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5E3R
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![BU of 5e3r by Molmil](/molmil-images/mine/5e3r) | Crystal structure of DapD in complex with 2-aminopimelate from Corynebacterium glutamicum | Descriptor: | (2S)-2-aminoheptanedioic acid, 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase | Authors: | Sagong, H.-Y, Kim, K.-J. | Deposit date: | 2015-10-03 | Release date: | 2015-11-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal Structure and Biochemical Characterization of Tetrahydrodipicolinate N-Succinyltransferase from Corynebacterium glutamicum. J.Agric.Food Chem., 63, 2015
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8G2N
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3MQ7
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![BU of 3mq7 by Molmil](/molmil-images/mine/3mq7) | Crystal Structure of Ectodomain Mutant of BST-2/Tetherin/CD317 | Descriptor: | Bone marrow stromal antigen 2, CALCIUM ION | Authors: | Xiong, Y, Yang, H, Wang, J, Meng, W. | Deposit date: | 2010-04-27 | Release date: | 2010-10-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural insight into the mechanisms of enveloped virus tethering by tetherin. Proc.Natl.Acad.Sci.USA, 107, 2010
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5EFY
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![BU of 5efy by Molmil](/molmil-images/mine/5efy) | Apo-form of SCO3201 | Descriptor: | Putative tetR-family transcriptional regulator | Authors: | Waack, P, Hinrichs, W. | Deposit date: | 2015-10-26 | Release date: | 2016-11-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structures of free and ligand-bound forms of the TetR/AcrR-like regulator SCO3201 from Streptomyces coelicolor suggest a novel allosteric mechanism. Febs J., 2022
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5TCX
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![BU of 5tcx by Molmil](/molmil-images/mine/5tcx) | Crystal structure of human tetraspanin CD81 | Descriptor: | CD81 antigen, CHOLESTEROL | Authors: | Zimmerman, B, McMillan, B.J, Seegar, T.C.M, Kruse, A.C, Blacklow, S.C. | Deposit date: | 2016-09-16 | Release date: | 2016-11-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.955 Å) | Cite: | Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket. Cell, 167, 2016
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4NTN
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![BU of 4ntn by Molmil](/molmil-images/mine/4ntn) | E.coli QueD, SeMet protein, 2A resolution | Descriptor: | 6-carboxy-5,6,7,8-tetrahydropterin synthase, FORMIC ACID, ZINC ION | Authors: | Bandarian, V, Roberts, S.A, Miles, Z.D. | Deposit date: | 2013-12-02 | Release date: | 2014-07-16 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Biochemical and Structural Studies of 6-Carboxy-5,6,7,8-tetrahydropterin Synthase Reveal the Molecular Basis of Catalytic Promiscuity within the Tunnel-fold Superfamily. J.Biol.Chem., 289, 2014
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3LS5
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![BU of 3ls5 by Molmil](/molmil-images/mine/3ls5) | Anti-tetrahydrocannabinol Fab Fragment, Free Form | Descriptor: | Heavy chain of antibody Fab fragment, Light chain of antibody Fab fragment | Authors: | Niemi, M.H, Rouvinen, J. | Deposit date: | 2010-02-12 | Release date: | 2010-06-02 | Last modified: | 2014-01-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A structural insight into the molecular recognition of a (-)-Delta9-tetrahydrocannabinol and the development of a sensitive, one-step, homogeneous immunocomplex-based assay for its detection J.Mol.Biol., 400, 2010
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5GCN
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![BU of 5gcn by Molmil](/molmil-images/mine/5gcn) | CATALYTIC DOMAIN OF TETRAHYMENA GCN5 HISTONE ACETYLTRANSFERASE IN COMPLEX WITH COENZYME A | Descriptor: | COENZYME A, HISTONE ACETYLTRANSFERASE GCN5 | Authors: | Lin, Y, Fletcher, C.M, Zhou, J, Allis, C.D, Wagner, G. | Deposit date: | 1999-03-24 | Release date: | 1999-07-19 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the catalytic domain of GCN5 histone acetyltransferase bound to coenzyme A Nature, 400, 1999
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6G1W
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![BU of 6g1w by Molmil](/molmil-images/mine/6g1w) | Crystal structure of Torpedo Californica acetylcholinesterase in complex with 2-{1-[2-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)ethyl]-1H-1,2,3-triazol-4-yl}-N-[4-(hydroxy)-3-methoxybenzyl]acetamide | Descriptor: | 2-[1-[2-[(3-chloranylacridin-9-yl)amino]ethyl]-1,2,3-triazol-4-yl]-~{N}-[(3-methoxy-4-oxidanyl-phenyl)methyl]ethanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ... | Authors: | Coquelle, N, Colletier, J.P. | Deposit date: | 2018-03-22 | Release date: | 2018-04-04 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Increasing Polarity in Tacrine and Huprine Derivatives: Potent Anticholinesterase Agents for the Treatment of Myasthenia Gravis. Molecules, 23, 2018
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6G6V
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3DCJ
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![BU of 3dcj by Molmil](/molmil-images/mine/3dcj) | Crystal structure of glycinamide formyltransferase (PurN) from Mycobacterium tuberculosis in complex with 5-methyl-5,6,7,8-tetrahydrofolic acid derivative | Descriptor: | CHLORIDE ION, MAGNESIUM ION, N-[4-({[(6S)-2-AMINO-4-HYDROXY-5-METHYL-5,6,7,8-TETRAHYDROPTERIDIN-6-YL]METHYL}AMINO)BENZOYL]-L-GLUTAMIC ACID, ... | Authors: | Zhang, Z, Squire, C.J, Baker, E.N. | Deposit date: | 2008-06-03 | Release date: | 2009-05-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structures of glycinamide ribonucleotide transformylase (PurN) from Mycobacterium tuberculosis reveal a novel dimer with relevance to drug discovery. J.Mol.Biol., 389, 2009
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