3FK6
Crystal structure of TetR triple mutant (H64K, S135L, S138I)
Summary for 3FK6
Entry DOI | 10.2210/pdb3fk6/pdb |
Related | 2O7O 2TCT 2VKE 2VKV 3FK7 |
Descriptor | Tetracycline repressor protein class B from transposon Tn10, Tetracycline repressor protein class D (2 entities in total) |
Functional Keywords | tetracycline repressor, bacterial transcription regulation, altered inducer specificity, 4-de-dimethylamino-anhydrotetracycline, antibiotic resistance, dna-binding, magnesium, metal-binding, repressor, transcription, transcription regulation, transposable element |
Biological source | Escherichia coli More |
Total number of polymer chains | 2 |
Total formula weight | 46897.60 |
Authors | Klieber, M.A.,Scholz, O.,Lochner, S.,Gmeiner, P.,Hillen, W.,Muller, Y.A. (deposition date: 2008-12-16, release date: 2009-10-27, Last modification date: 2023-11-01) |
Primary citation | Klieber, M.A.,Scholz, O.,Lochner, S.,Gmeiner, P.,Hillen, W.,Muller, Y.A. Structural origins for selectivity and specificity in an engineered bacterial repressor-inducer pair. Febs J., 276:5610-5621, 2009 Cited by PubMed: 19712110DOI: 10.1111/j.1742-4658.2009.07254.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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