3FK6

Crystal structure of TetR triple mutant (H64K, S135L, S138I)

Summary for 3FK6

Entry DOI	10.2210/pdb3fk6/pdb
Related	2O7O 2TCT 2VKE 2VKV 3FK7
Descriptor	Tetracycline repressor protein class B from transposon Tn10, Tetracycline repressor protein class D (2 entities in total)
Functional Keywords	tetracycline repressor, bacterial transcription regulation, altered inducer specificity, 4-de-dimethylamino-anhydrotetracycline, antibiotic resistance, dna-binding, magnesium, metal-binding, repressor, transcription, transcription regulation, transposable element
Biological source	Escherichia coli More
Total number of polymer chains	2
Total formula weight	46897.60
Authors	Klieber, M.A.,Scholz, O.,Lochner, S.,Gmeiner, P.,Hillen, W.,Muller, Y.A. (deposition date: 2008-12-16, release date: 2009-10-27, Last modification date: 2023-11-01)
Primary citation	Klieber, M.A.,Scholz, O.,Lochner, S.,Gmeiner, P.,Hillen, W.,Muller, Y.A. Structural origins for selectivity and specificity in an engineered bacterial repressor-inducer pair. Febs J., 276:5610-5621, 2009 Cited by PubMed: 19712110 DOI: 10.1111/j.1742-4658.2009.07254.x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation