6G6V

Phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis in complex with 4-(2-carboxybenzoyl)-2-nitrobenzoic acid at 1.9A resolution.

Summary for 6G6V

Entry DOI	10.2210/pdb6g6v/pdb
Descriptor	Phosphopantetheine adenylyltransferase, 4-(2-carboxyphenyl)carbonyl-2-nitro-benzoic acid (3 entities in total)
Functional Keywords	coad, ppat, transferase, complex
Biological source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Total number of polymer chains	1
Total formula weight	18107.62
Authors	Blaszczyk, M.,Blundell, T.L. (deposition date: 2018-04-03, release date: 2019-04-10, Last modification date: 2024-01-17)
Primary citation	Blaszczyk, M.,El Bakali, J.,Boland, J.A.,Spry, C.,Dias, M.,Blundell, T.L.,Abel, C. Fragment linking applied to the discovery of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase inhibitors To Be Published,
Experimental method	X-RAY DIFFRACTION (1.942 Å)

Structure validation