6G6V
Phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis in complex with 4-(2-carboxybenzoyl)-2-nitrobenzoic acid at 1.9A resolution.
Summary for 6G6V
Entry DOI | 10.2210/pdb6g6v/pdb |
Descriptor | Phosphopantetheine adenylyltransferase, 4-(2-carboxyphenyl)carbonyl-2-nitro-benzoic acid (3 entities in total) |
Functional Keywords | coad, ppat, transferase, complex |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Total number of polymer chains | 1 |
Total formula weight | 18107.62 |
Authors | Blaszczyk, M.,Blundell, T.L. (deposition date: 2018-04-03, release date: 2019-04-10, Last modification date: 2024-01-17) |
Primary citation | Blaszczyk, M.,El Bakali, J.,Boland, J.A.,Spry, C.,Dias, M.,Blundell, T.L.,Abel, C. Fragment linking applied to the discovery of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase inhibitors To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.942 Å) |
Structure validation
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