PDB: 225158 resultsInfo pagesStatus searchChemie searchBIRD

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4XVI	Binary complex of human polymerase nu and DNA with the finger domain ajar Descriptor: DNA (5'-D(*AP*CP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*AP*GP*CP*GP*TP*CP*AP*G)-3'), DNA polymerase nu Authors: Lee, Y.-S, Yang, W. Deposit date: 2015-01-27 Release date: 2015-03-11 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.1 Å) Cite: How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis. Nat.Struct.Mol.Biol., 22, 2015
6PLG	Crystal structure of human PHGDH complexed with Compound 15 Descriptor: (2S)-(4-{3-[(4,5-dichloro-1-methyl-1H-indole-2-carbonyl)amino]oxetan-3-yl}phenyl)(pyridin-3-yl)acetic acid, D-3-phosphoglycerate dehydrogenase, D-MALATE Authors: Olland, A, Lakshminarasimhan, D, White, A, Suto, R.K. Deposit date: 2019-06-30 Release date: 2019-07-24 Last modified: 2019-09-04 Method: X-RAY DIFFRACTION (2.93 Å) Cite: Inhibition of 3-phosphoglycerate dehydrogenase (PHGDH) by indole amides abrogates de novo serine synthesis in cancer cells. Bioorg.Med.Chem.Lett., 29, 2019
6DZC	Solution structure of Rbfox2 RRM mimetic peptide CPfox6 Descriptor: CPfox6 Authors: Sun, Y.-T, Varani, G. Deposit date: 2018-07-03 Release date: 2019-05-15 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: A Small Cyclic beta-Hairpin Peptide Mimics the Rbfox2 RNA Recognition Motif and Binds to the Precursor miRNA 20b. Chembiochem, 20, 2019
6P2E	Structure of Aedes aegypti OBP22 in the complex with benzaldehyde Descriptor: BENZOIC ACID, GLYCEROL, OBP22, ... Authors: Jones, D.N, Murphy, E. Deposit date: 2019-05-21 Release date: 2019-07-31 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Aedes aegypti Odorant Binding Protein 22 selectively binds fatty acids through a conformational change in its C-terminal tail. Sci Rep, 10, 2020
6DZE	Solution structure of Rbfox2 RRM mimetic peptide CPfox7 Descriptor: CPfox7 Authors: Sun, Y.-T, Varani, G. Deposit date: 2018-07-03 Release date: 2019-05-15 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: A Small Cyclic beta-Hairpin Peptide Mimics the Rbfox2 RNA Recognition Motif and Binds to the Precursor miRNA 20b. Chembiochem, 20, 2019
6P2K	Crystal structure of AFV00434, an ancestral GH74 enzyme Descriptor: 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ACETATE ION, CHLORIDE ION, ... Authors: Stogios, P.J, Skarina, T, Arnal, G, Brumer, H, Savchenko, A. Deposit date: 2019-05-21 Release date: 2019-07-31 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Substrate specificity, regiospecificity, and processivity in glycoside hydrolase family 74. J.Biol.Chem., 294, 2019
6EE9	Cytokine-like Peptide Stress-response Peptide-1 from Manduca Sexta Descriptor: Stress-response Peptide-1 Authors: Schrag, L. Deposit date: 2018-08-13 Release date: 2019-08-21 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: NMR Solution Structure and Expression Profile of Stress Response Peptide-1: A Cytokine from Manduca sexta To be published
3KH8	Crystal structure of MaoC-like dehydratase from Phytophthora Capsici Descriptor: MaoC-like dehydratase Authors: Wang, H, Zhang, K, Guo, J, Zhou, Q, Zheng, X, Sun, F, Pang, H, Zhang, X. Deposit date: 2009-10-30 Release date: 2010-11-10 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of MaoC-like dehydratase from Phytophthora Capsici To be Published
6P6U	Crystal Structure of Monoclinic Rabbit Muscle Lactate Dehydrogenase with Four Tetramers as the Asymmetric Unit Descriptor: ADENOSINE MONOPHOSPHATE, L-lactate dehydrogenase A chain Authors: McPherson, A. Deposit date: 2019-06-04 Release date: 2020-06-17 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.42 Å) Cite: Crystal Structure of Monoclinic Rabbit Muscle Lactate Dehydrogenase with Four Tetramers as the Asymmetric Unit to be published
7S7T	iNicSnFR3a Nicotine Sensor comprising Periplasmic Binding sequence plus Fluorescent Sequence with varenicline bound Descriptor: IODIDE ION, VARENICLINE, iNicSnFR 3.0 Fluorescent Nicotine Sensor Authors: Fan, C, Shivange, A.V, Looger, L.L, Lester, H.A, Rees, D.C. Deposit date: 2021-09-17 Release date: 2021-10-13 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Correction: Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands. Elife, 11, 2022
4XGX	Crystal structure of Escherichia coli Flavin trafficking protein, an FMN transferase, Y60N mutant, ADP-inhibited Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, FAD:protein FMN transferase, ... Authors: Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V. Deposit date: 2015-01-02 Release date: 2015-12-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Molecular insights into the enzymatic diversity of flavin-trafficking protein (Ftp; formerly ApbE) in flavoprotein biogenesis in the bacterial periplasm. Microbiologyopen, 5, 2016
3KJD	Human poly(ADP-ribose) polymerase 2, catalytic fragment in complex with an inhibitor ABT-888 Descriptor: (2R)-2-(7-carbamoyl-1H-benzimidazol-2-yl)-2-methylpyrrolidinium, GLYCEROL, Poly [ADP-ribose] polymerase 2 Authors: Karlberg, T, Schutz, P, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Kotzsch, A, Kraulis, P, Nielsen, T.K, Moche, M, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Siponen, M.I, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC) Deposit date: 2009-11-03 Release date: 2009-11-17 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal structure of the catalytic domain of human PARP2 in complex with PARP inhibitor ABT-888. Biochemistry, 49, 2010
3KHV	Crystal Structures of Urokinase-type Plasminogen Activator in Complex with 4-(Aminomethyl) Benzoic Acid and 4-(Aminomethyl-phenyl)-methanol Descriptor: SULFATE ION, TRIETHYLENE GLYCOL, Urokinase-type plasminogen activator, ... Authors: Jiang, L.-G, Zhao, G.-X, Bian, X.-B, Yuan, C, Huang, Z.-X, Huang, M.-D. Deposit date: 2009-10-30 Release date: 2009-12-01 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Crystal Structures of Urokinase-type Plasminogen Activator in Complex with 4-(Aminomethyl) Benzoic Acid and 4-(Aminomethyl-phenyl)-methanol CHIN.J.STRUCT.CHEM., 28, 2009
6P4E	Leishmania mexicana CPB in complex with an aza-nitrile inhibitor Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-tert-butyl-N-[(2S)-1-(2-cyano-1,2-dimethylhydrazinyl)-4-methyl-1-oxopentan-2-yl]-1-methyl-1H-pyrazole-5-carboxamide (non-preferred name), ... Authors: Ribeiro, J.F.R, Li, C, De Vita, D, Emsley, J, Montanari, C.A. Deposit date: 2019-05-27 Release date: 2020-06-03 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.35 Å) Cite: High Resolution X-Ray Crystal Structures of LmCPB2.8 Co-Crystalized with Dipeptidyl Aza-nitrile Inhibitor and Structure Activity Relationships To Be Published
3KIA	Crystal structure of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus Descriptor: CHLORIDE ION, GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ... Authors: Macedo-Ribeiro, S, Pereira, P.J.B, Empadinhas, N, da Costa, M.S. Deposit date: 2009-11-01 Release date: 2010-11-03 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Functional and structural characterization of a novel mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus reveals its dual substrate specificity Mol.Microbiol., 79, 2011
6P4J	Mouse norovirus complexed with GCDCA Descriptor: Capsid protein, GLYCOCHENODEOXYCHOLIC ACID Authors: Smith, T.J, Smith, T.J. Deposit date: 2019-05-27 Release date: 2019-08-07 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Bile Salts Alter the Mouse Norovirus Capsid Conformation: Possible Implications for Cell Attachment and Immune Evasion. J.Virol., 93, 2019
7S7X	Crystal structure of iCytSnFR Cytisine Sensor precursor binding protein with varenicline bound Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, DI(HYDROXYETHYL)ETHER, VARENICLINE, ... Authors: Fan, C, Nichols, N.L, Luebbert, L, Looger, L.L, Lester, H.A, Rees, D.C. Deposit date: 2021-09-17 Release date: 2021-10-13 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structure, Function, and Application of Bacterial ABC Transporters Ph.D.Thesis,California Institute of Technology, 2020
6P5E	Photoactive Yellow Protein PYP 80ps Descriptor: Photoactive yellow protein Authors: Pandey, S, Schmidt, M. Deposit date: 2019-05-30 Release date: 2019-09-18 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Time-resolved serial femtosecond crystallography at the European XFEL. Nat.Methods, 17, 2020
7S7U	Crystal structure of iNicSnFR3a Fluorescent Nicotine Sensor with nicotine bound Descriptor: iNicSnFR 3.0 Fluorescent Nicotine Sensor Authors: Fan, C, Shivange, A.V, Looger, L.L, Lester, H.A, Rees, D.C. Deposit date: 2021-09-17 Release date: 2021-10-13 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Correction: Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands. Elife, 11, 2022
6P69	Crystal structure of FGFR1-Y563C (FGFR4 surrogate) covalently bound to compound 11. Descriptor: 1,2-ETHANEDIOL, Fibroblast growth factor receptor 1, N-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl][3-(4-methylpiperazin-1-yl)propyl]amino}pyrimidin-4-yl)amino]phenyl}prop-2-enamide, ... Authors: Larsen, N.A. Deposit date: 2019-06-03 Release date: 2019-06-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.2 Å) Cite: To be published TBD
4CZW	Structure of the Neurospora crassa Pan2 catalytic unit (protease and nuclease domain) Descriptor: PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN2, ZINC ION Authors: Christie, M, Izaurralde, E, Weichenrieder, O. Deposit date: 2014-04-22 Release date: 2014-06-04 Last modified: 2014-07-16 Method: X-RAY DIFFRACTION (2.6 Å) Cite: An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay. Nat.Struct.Mol.Biol., 21, 2014
6OZD	Crystal structure of Putative exported protein (BPSS2145) from Burkholderia pseudomallei K96243 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Putative exported protein Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2019-05-15 Release date: 2019-06-12 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Crystal structure of Putative exported protein (BPSS2145) from Burkholderia pseudomallei K96243 TO BE PUBLISHED
4D05	Structure and activity of a minimal-type ATP-dependent DNA ligase from a psychrotolerant bacterium Descriptor: ADENOSINE MONOPHOSPHATE, ATP-DEPENDENT DNA LIGASE, MAGNESIUM ION, ... Authors: Williamson, A, Rothweiler, U, Leiros, H.-K.S. Deposit date: 2014-04-24 Release date: 2014-11-12 Last modified: 2019-06-26 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Enzyme-Adenylate Structure of a Bacterial ATP-Dependent DNA Ligase with a Minimized DNA-Binding Surface Acta Crystallogr.,Sect.D, 70, 2014
7SH3	Crystal Structure of a VirB8-like Protein of Type IV Secretion System from Rickettsia typhi in Complex with a Synthetic VirB8 Miniprotein Binder Descriptor: Synthetic VirB8 Miniprotein Binder, VirB8-like protein of type IV secretion system Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2021-10-07 Release date: 2021-10-20 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3 Å) Cite: Crystal Structure of a VirB8-like Protein of Type IV Secretion System from Rickettsia typhi in Complex with a Synthetic VirB8 Miniprotein Binder to be published
6EYY	Anti-CRISPR AcrIIa6 cubic form Descriptor: AcrIIa6 Authors: Cambillau, C, Amigues, B, Moineau, S. Deposit date: 2017-11-13 Release date: 2018-06-06 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins. Nat Commun, 9, 2018

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