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1N51
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BU of 1n51 by Molmil
Aminopeptidase P in complex with the inhibitor apstatin
Descriptor: MANGANESE (II) ION, Xaa-Pro aminopeptidase, apstatin
Authors:Graham, S.C, Maher, M.J, Lee, M.H, Simmons, W.H, Freeman, H.C, Guss, J.M.
Deposit date:2002-11-03
Release date:2003-12-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of Escherichia coli aminopeptidase P in complex with the inhibitor apstatin.
Acta Crystallogr.,Sect.D, 60, 2004
1BOA
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BU of 1boa by Molmil
HUMAN METHIONINE AMINOPEPTIDASE 2 COMPLEXED WITH ANGIOGENESIS INHIBITOR FUMAGILLIN
Descriptor: COBALT (II) ION, FUMAGILLIN, METHIONINE AMINOPEPTIDASE
Authors:Liu, S, Widom, J, Kemp, C.W, Crews, C.M, Clardy, J.C.
Deposit date:1998-08-01
Release date:1999-08-01
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of human methionine aminopeptidase-2 complexed with fumagillin.
Science, 282, 1998
3H8F
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BU of 3h8f by Molmil
High pH native structure of leucine aminopeptidase from Pseudomonas putida
Descriptor: BICARBONATE ION, Cytosol aminopeptidase, MANGANESE (II) ION, ...
Authors:Kale, A, Dijkstra, B.W, Sonke, T, Thunnissen, A.M.W.H.
Deposit date:2009-04-29
Release date:2010-04-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the leucine aminopeptidase from Pseudomonas putida reveals the molecular basis for its enantioselectivity and broad substrate specificity.
J.Mol.Biol., 398, 2010
4K5O
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BU of 4k5o by Molmil
Phosphonic Arginine Mimetics as Inhibitors of the M1 Aminopeptidases from Plasmodium falciparum
Descriptor: GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ...
Authors:McGowan, S.
Deposit date:2013-04-15
Release date:2013-06-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Synthesis and Structure-Activity Relationships of Phosphonic Arginine Mimetics as Inhibitors of the M1 and M17 Aminopeptidases from Plasmodium falciparum.
J.Med.Chem., 56, 2013
1BPN
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BU of 1bpn by Molmil
DIFFERENTIATION AND IDENTIFICATION OF THE TWO CATALYTIC METAL BINDING SITES IN BOVINE LENS LEUCINE AMINOPEPTIDASE BY X-RAY CRYSTALLOGRAPHY
Descriptor: LEUCINE AMINOPEPTIDASE, ZINC ION
Authors:Kim, H, Lipscomb, W.N.
Deposit date:1993-03-02
Release date:1993-07-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Differentiation and identification of the two catalytic metal binding sites in bovine lens leucine aminopeptidase by x-ray crystallography.
Proc.Natl.Acad.Sci.USA, 90, 1993
3IU8
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BU of 3iu8 by Molmil
M. tuberculosis methionine aminopeptidase with Ni inhibitor T03
Descriptor: 3-[(4-fluorobenzyl)sulfanyl]-4H-1,2,4-triazole, CHLORIDE ION, Methionine aminopeptidase, ...
Authors:Ye, Q.Z, Lu, J.P.
Deposit date:2009-08-30
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
J.Med.Chem., 53, 2010
3IU9
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BU of 3iu9 by Molmil
M. tuberculosis methionine aminopeptidase with Ni inhibitor T07
Descriptor: 5-[(2,4-dichlorobenzyl)sulfanyl]-4H-1,2,4-triazol-3-amine, CHLORIDE ION, Methionine aminopeptidase, ...
Authors:Ye, Q.Z, Lu, J.P.
Deposit date:2009-08-30
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
J.Med.Chem., 53, 2010
1BLL
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BU of 1bll by Molmil
X-RAY CRYSTALLOGRAPHIC DETERMINATION OF THE STRUCTURE OF BOVINE LENS LEUCINE AMINOPEPTIDASE COMPLEXED WITH AMASTATIN: FORMULATION OF A CATALYTIC MECHANISM FEATURING A GEM-DIOLATE TRANSITION STATE
Descriptor: AMASTATIN, LEUCINE AMINOPEPTIDASE, ZINC ION
Authors:Kim, H, Lipscomb, W.N.
Deposit date:1993-03-02
Release date:1994-01-31
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:X-ray crystallographic determination of the structure of bovine lens leucine aminopeptidase complexed with amastatin: formulation of a catalytic mechanism featuring a gem-diolate transition state.
Biochemistry, 32, 1993
1BPM
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BU of 1bpm by Molmil
DIFFERENTIATION AND IDENTIFICATION OF THE TWO CATALYTIC METAL BINDING SITES IN BOVINE LENS LEUCINE AMINOPEPTIDASE BY X-RAY CRYSTALLOGRAPHY
Descriptor: LEUCINE AMINOPEPTIDASE, MAGNESIUM ION, ZINC ION
Authors:Kim, H, Lipscomb, W.N.
Deposit date:1993-03-02
Release date:1993-07-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Differentiation and identification of the two catalytic metal binding sites in bovine lens leucine aminopeptidase by x-ray crystallography.
Proc.Natl.Acad.Sci.USA, 90, 1993
1QXY
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BU of 1qxy by Molmil
Crystal structure of S. aureus methionine aminopeptidase in complex with a ketoheterocycle 618
Descriptor: (2S)-2-AMINO-4-(METHYLSULFANYL)-1-PYRIDIN-2-YLBUTANE-1,1-DIOL, ACETATE ION, COBALT (II) ION, ...
Authors:Douangamath, A, Dale, G.E, D'Arcy, A, Oefner, C.
Deposit date:2003-09-09
Release date:2004-03-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:Crystal structures of staphylococcusaureus methionine aminopeptidase complexed with keto heterocycle and aminoketone inhibitors reveal the formation of a tetrahedral intermediate.
J.Med.Chem., 47, 2004
1QZY
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BU of 1qzy by Molmil
Human Methionine Aminopeptidase in complex with bengamide inhibitor LAF153 and cobalt
Descriptor: (E)-(2R,3R,4S,5R)-3,4,5-TRIHYDROXY-2-METHOXY-8,8-DIMETHYL-NON-6-ENOIC ACID ((3S,6R)-6-HYDROXY-2-OXO-AZEPAN-3-YL)-AMIDE, COBALT (II) ION, Methionine aminopeptidase 2, ...
Authors:Eck, M.J, Song, H.K, Morollo, A.
Deposit date:2003-09-18
Release date:2003-11-25
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Proteomics-based target identification: bengamides as a new class of methionine aminopeptidase inhibitors.
J.Biol.Chem., 278, 2003
3OR3
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BU of 3or3 by Molmil
Restriction endonuclease HPY188I in complex with product DNA
Descriptor: 5'-D(*GP*AP*TP*CP*T)-3', 5'-D(*GP*TP*TP*CP*A)-3', 5'-D(P*GP*AP*AP*C)-3', ...
Authors:Sokolowska, M, Czapinska, H, Bochtler, M.
Deposit date:2010-09-06
Release date:2010-10-20
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Hpy188I-DNA pre- and post-cleavage complexes--snapshots of the GIY-YIG nuclease mediated catalysis.
Nucleic Acids Res., 39, 2011
1QXZ
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BU of 1qxz by Molmil
Crystal structure of S. aureus methionine aminopeptidase in complex with a ketoheterocycle inhibitor 119
Descriptor: (2S)-2-AMINO-4-(METHYLSULFANYL)-1-(1,3-THIAZOL-2-YL)BUTANE-1,1-DIOL, COBALT (II) ION, methionyl aminopeptidase
Authors:Douangamath, A, Dale, G.E, D'Arcy, A, Oefner, C.
Deposit date:2003-09-09
Release date:2004-03-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystal structures of staphylococcusaureus methionine aminopeptidase complexed with keto heterocycle and aminoketone inhibitors reveal the formation of a tetrahedral intermediate.
J.Med.Chem., 47, 2004
1R5H
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BU of 1r5h by Molmil
Crystal Structure of MetAP2 complexed with A320282
Descriptor: MANGANESE (II) ION, Methionine aminopeptidase 2, N'-(2S,3R)-3-AMINO-4-CYCLOHEXYL-2-HYDROXY-BUTANO-N-(4-METHYLPHENYL)HYDRAZIDE
Authors:Sheppard, G.S, Wang, J, Kawai, M, BaMaung, N.Y, Craig, R.A, Erickson, S.A, Lynch, L, Patel, J, Yang, F, Searle, X.B, Lou, P, Park, C, Kim, K.H, Henkin, J, Lesniewski, R.
Deposit date:2003-10-10
Release date:2004-10-12
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2.
Bioorg.Med.Chem.Lett., 14, 2004
1R58
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BU of 1r58 by Molmil
Crystal Structure of MetAP2 complexed with A357300
Descriptor: MANGANESE (II) ION, Methionine aminopeptidase 2, N'-((2S,3R)-3-AMINO-2-HYDROXY-5-(ISOPROPYLSULFANYL)PENTANOYL)-N-3-CHLOROBENZOYL HYDRAZIDE
Authors:Sheppard, G.S, Wang, J, Kawai, M, BaMaung, N.Y, Craig, R.A, Ericken, S.A, Lynch, L, Patel, J, Yang, F, Searle, X.B, Lou, P, Park, C, Kim, K.H, Henkin, J, Lesniewski, R.
Deposit date:2003-10-09
Release date:2004-10-12
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2.
Bioorg.Med.Chem.Lett., 14, 2004
5W2V
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BU of 5w2v by Molmil
Crystal structure of mutant CJ YCEI protein (CJ-G34C) with selenocysteine guest structure
Descriptor: Putative periplasmic protein, SELENOCYSTEINE, SULFATE ION, ...
Authors:Huber, T.R, Snow, C.D.
Deposit date:2017-06-07
Release date:2018-01-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Installing Guest Molecules at Specific Sites within Scaffold Protein Crystals.
Bioconjug. Chem., 29, 2018
5VTT
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BU of 5vtt by Molmil
Dehaloperoxidase B Y38F mutant
Descriptor: Dehaloperoxidase B, GLYCEROL, OXYGEN MOLECULE, ...
Authors:Carey, L.M, Ghiladi, R.A.
Deposit date:2017-05-18
Release date:2018-05-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:Probing the Structure-Function Relationship of a Multifunctional Enzyme using Crystallographic Diffraction Methods
Thesis, North Carolina State University, 2017
5W2D
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BU of 5w2d by Molmil
Crystal structure of mutant CJ YCEI protein (CJ-G34C) for nanotechnology applications
Descriptor: Polyisoprenoid-binding protein, SULFATE ION, UNKNOWN LIGAND
Authors:Huber, T.R, Snow, C.D.
Deposit date:2017-06-06
Release date:2018-01-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Installing Guest Molecules at Specific Sites within Scaffold Protein Crystals.
Bioconjug. Chem., 29, 2018
5W30
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BU of 5w30 by Molmil
Crystal structure of mutant CJ YCEI protein (CJ-N48C) with monobromobimane guest structure
Descriptor: 3-(bromomethyl)-2,5,6-trimethyl-1H,7H-pyrazolo[1,2-a]pyrazole-1,7-dione, Putative periplasmic protein, SULFATE ION, ...
Authors:Huber, T.R, Snow, C.D.
Deposit date:2017-06-07
Release date:2018-01-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Installing Guest Molecules at Specific Sites within Scaffold Protein Crystals.
Bioconjug. Chem., 29, 2018
3PHJ
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BU of 3phj by Molmil
Shikimate 5-Dehydrogenase (aroE) from Helicobacter pylori in complex with 3-Dehydroshikimate
Descriptor: 3-DEHYDROSHIKIMATE, Shikimate dehydrogenase
Authors:Cheng, W.C, Lin, S.C, Lin, C.H, Wang, W.C.
Deposit date:2010-11-04
Release date:2011-11-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Shikimate 5-Dehydrogenase (aroE) from Helicobacter pylori in complex with 3-Dehydroshikimate
To be Published
5W32
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BU of 5w32 by Molmil
Crystal structure of mutant CJ YCEI protein (CJ-N48C) with selenocysteine guest structure
Descriptor: Putative periplasmic protein, SELENOCYSTEINE, SULFATE ION, ...
Authors:Huber, T.R, Snow, C.D.
Deposit date:2017-06-07
Release date:2018-01-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Installing Guest Molecules at Specific Sites within Scaffold Protein Crystals.
Bioconjug. Chem., 29, 2018
5W3C
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BU of 5w3c by Molmil
Crystal structure of mutant CJ YCEI protein (CJ-N182C) with selenocysteine guest structure
Descriptor: EICOSANE, Polyisoprenoid-binding protein, SELENOCYSTEINE, ...
Authors:Huber, T.R, Snow, C.D.
Deposit date:2017-06-07
Release date:2018-01-03
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Installing Guest Molecules at Specific Sites within Scaffold Protein Crystals.
Bioconjug. Chem., 29, 2018
3QHP
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BU of 3qhp by Molmil
Crystal structure of the catalytic domain of cholesterol-alpha-glucosyltransferase from Helicobacter pylori
Descriptor: Type 1 capsular polysaccharide biosynthesis protein J (CapJ)
Authors:Lee, S.J, Lee, B.I, Suh, S.W.
Deposit date:2011-01-26
Release date:2011-06-29
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the catalytic domain of cholesterol-alpha-glucosyltransferase from Helicobacter pylori
Proteins, 79, 2011
5VTS
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BU of 5vts by Molmil
Dehaloperoxidase B Y28F mutant
Descriptor: Dehaloperoxidase B, GLYCEROL, OXYGEN MOLECULE, ...
Authors:Carey, L.M, Ghiladi, R.A.
Deposit date:2017-05-18
Release date:2018-05-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.571 Å)
Cite:Probing the Structure-Function Relationship of a Multifunctional Enzyme using Crystallographic Diffraction Methods
Thesis, North Carolina State University, 2017
5W2Z
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BU of 5w2z by Molmil
Crystal structure of mutant CJ YCEI protein (CJ-N48C) with 5-mercapto-2-nitrobenzoic acid guest structure
Descriptor: 5-MERCAPTO-2-NITRO-BENZOIC ACID, Putative periplasmic protein, SULFATE ION, ...
Authors:Huber, T.R, Snow, C.D.
Deposit date:2017-06-07
Release date:2018-01-03
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Installing Guest Molecules at Specific Sites within Scaffold Protein Crystals.
Bioconjug. Chem., 29, 2018

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