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4ZCG
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Crystal Structure of human GGT1 in complex with Glutamate (with all atoms of glutamate)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLUTAMIC ACID, ...
Authors:Terzyan, S, Hanigan, M.
Deposit date:2015-04-15
Release date:2015-06-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Human gamma-Glutamyl Transpeptidase 1: STRUCTURES OF THE FREE ENZYME, INHIBITOR-BOUND TETRAHEDRAL TRANSITION STATES, AND GLUTAMATE-BOUND ENZYME REVEAL NOVEL MOVEMENT WITHIN THE ACTIVE SITE DURING CATALYSIS.
J.Biol.Chem., 290, 2015
2ZJI
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BU of 2zji by Molmil
Crystal structure of the human BACE1 catalytic domain in complex with N-[1-(2,6-dimethoxy-benzyl)-piperidin-4-yl]-4-mercapto-butyramide
Descriptor: Beta-secretase 1, N-[1-(2,6-dimethoxybenzyl)piperidin-4-yl]-4-sulfanylbutanamide
Authors:Randal, M, Lam, M.B, Romanowski, M.J.
Deposit date:2008-03-07
Release date:2009-01-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Fragment-based discovery of novel BACE1 inhibitors using Tethering technology
To be Published
4TYU
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BU of 4tyu by Molmil
Homodimeric Single Domain Antibody (sdAb) against Staphylococcal enterotoxin B (SEB)
Descriptor: SULFATE ION, Single Domain Antibody
Authors:Legler, P.M.
Deposit date:2014-07-09
Release date:2014-09-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structural and mutational analysis of a monomeric and dimeric form of a single domain antibody with implications for protein misfolding.
Proteins, 82, 2014
6HMX
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BU of 6hmx by Molmil
RIP2 Kinase Catalytic Domain complex with N(4,5dimethyl1Hpyrazol3yl)7methoxy6(2methylpropane2sulfonyl)quinolin4amine
Descriptor: 6-~{tert}-butylsulfonyl-~{N}-(3,4-dimethyl-1~{H}-pyrazol-5-yl)-7-methoxy-quinolin-4-amine, Receptor-interacting serine/threonine-protein kinase 2
Authors:Convery, M.A, Haile, P.A.
Deposit date:2018-09-13
Release date:2018-11-07
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel.
ACS Med Chem Lett, 9, 2018
4TXY
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BU of 4txy by Molmil
Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase, a prokaryotic cGAS homolog
Descriptor: Cyclic AMP-GMP synthase, MAGNESIUM ION
Authors:Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A.
Deposit date:2014-07-07
Release date:2014-08-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.0001 Å)
Cite:Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity.
Cell, 158, 2014
6V10
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BU of 6v10 by Molmil
genome-containing AAV8 particles
Descriptor: Capsid protein, DNA (5'-D(*CP*A)-3')
Authors:Mietzsch, M, Agbandje-McKenna, M.
Deposit date:2019-11-19
Release date:2019-12-11
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.77 Å)
Cite:Comparative Analysis of the Capsid Structures of AAVrh.10, AAVrh.39, and AAV8.
J.Virol., 94, 2020
5JMR
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BU of 5jmr by Molmil
X-ray structure of the furin inhibitory antibody Nb14
Descriptor: CHLORIDE ION, camelid VHH fragment
Authors:Dahms, S.O, Than, M.E.
Deposit date:2016-04-29
Release date:2016-12-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:The structure of a furin-antibody complex explains non-competitive inhibition by steric exclusion of substrate conformers.
Sci Rep, 6, 2016
1NR8
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BU of 1nr8 by Molmil
The crystal structure of a D-Lysine-based chiral PNA-DNA duplex
Descriptor: 5'-D(P*AP*GP*TP*GP*AP*TP*CP*TP*AP*C)-3', H-((GPN)*(TPN)*(APN)*(GPN)*(A66)*(T66)*(C66)*(APN)*(CPN)*(TPN))-NH2, MAGNESIUM ION
Authors:Menchise, V, De Simone, G, Tedeschi, T, Corradini, R, Sforza, S, Marchelli, R, Capasso, D, Saviano, M, Pedone, C.
Deposit date:2003-01-24
Release date:2003-10-28
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Insights into peptide nucleic acid (PNA) structural features: The crystal structure of a D-lysine-based chiral PNA-DNA duplex
Proc.Natl.Acad.Sci.USA, 100, 2003
7RZ8
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BU of 7rz8 by Molmil
Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist quisqualate
Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Glutamate receptor 2
Authors:Klykov, O.V, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I.
Deposit date:2021-08-27
Release date:2021-10-27
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L.
Mol.Cell, 81, 2021
7RZA
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BU of 7rza by Molmil
Structure of the complex of AMPA receptor GluA2 with auxiliary subunit GSG1L bound to agonist quisqualate
Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2
Authors:Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I.
Deposit date:2021-08-27
Release date:2021-10-27
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (4.26 Å)
Cite:Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L.
Mol.Cell, 81, 2021
7RZ6
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BU of 7rz6 by Molmil
Structure of the complex of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist glutamate
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Klykov, O.V, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I.
Deposit date:2021-08-27
Release date:2021-10-27
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L.
Mol.Cell, 81, 2021
7RYZ
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BU of 7ryz by Molmil
Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit GSG1L bound to agonist quisqualate
Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2
Authors:Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I.
Deposit date:2021-08-26
Release date:2021-10-27
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (4.15 Å)
Cite:Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L.
Mol.Cell, 81, 2021
4U7S
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BU of 4u7s by Molmil
Homodimeric Single Domain Antibody (sdAb) against Staphylococcal enterotoxin B (SEB) Crystallized for 5 months
Descriptor: SULFATE ION, sdAb A3
Authors:Legler, P.M.
Deposit date:2014-07-31
Release date:2014-09-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural and mutational analysis of a monomeric and dimeric form of a single domain antibody with implications for protein misfolding.
Proteins, 82, 2014
7RYY
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BU of 7ryy by Molmil
Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist glutamate
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Klykov, O.V, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I.
Deposit date:2021-08-26
Release date:2021-10-27
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L.
Mol.Cell, 81, 2021
7RZ5
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BU of 7rz5 by Molmil
Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK 200775
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Glutamate receptor 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
Authors:Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I.
Deposit date:2021-08-27
Release date:2021-10-27
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L.
Mol.Cell, 81, 2021
7RZ9
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BU of 7rz9 by Molmil
Structure of the complex of AMPA receptor GluA2 with auxiliary subunit GSG1L in the apo state
Descriptor: Glutamate receptor 2
Authors:Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I.
Deposit date:2021-08-27
Release date:2021-10-27
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (4.15 Å)
Cite:Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L.
Mol.Cell, 81, 2021
7RZ4
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BU of 7rz4 by Molmil
Structure of the complex of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK 200775
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2, ...
Authors:Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I.
Deposit date:2021-08-27
Release date:2021-10-27
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L.
Mol.Cell, 81, 2021
1JQW
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BU of 1jqw by Molmil
THE 2.3 ANGSTROM RESOLUTION STRUCTURE OF BACILLUS SUBTILIS LUXS/HOMOCYSTEINE COMPLEX
Descriptor: 2-AMINO-4-MERCAPTO-BUTYRIC ACID, Autoinducer-2 production protein luxS, ZINC ION
Authors:Ruzheinikov, S.N, Das, S.K, Sedelnikova, S.E, Hartley, A, Foster, S.J, Horsburgh, M.J, Cox, A.G, McCleod, C.W, Mekhalfia, A, Blackburn, G.M, Rice, D.W, Baker, P.J.
Deposit date:2001-08-09
Release date:2001-10-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The 1.2 A structure of a novel quorum-sensing protein, Bacillus subtilis LuxS
J.Mol.Biol., 313, 2001
7RZ7
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BU of 7rz7 by Molmil
Structure of the complex of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist Quisqualate
Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2
Authors:Klykov, O.V, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I.
Deposit date:2021-08-27
Release date:2021-10-27
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L.
Mol.Cell, 81, 2021
4TZP
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BU of 4tzp by Molmil
As Grown, Untreated Co-crystals of the Ternary Complex Containing a T-box Stem I RNA, its cognate tRNAGly, and B. subtilis YbxF protein
Descriptor: Ribosome-associated protein L7Ae-like, engineered tRNA, glyQ T-box Stem I
Authors:Zhang, J, Ferre-D'Amare, A.R.
Deposit date:2014-07-10
Release date:2014-09-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (8.503 Å)
Cite:Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration.
Structure, 22, 2014
4TZZ
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BU of 4tzz by Molmil
Co-crystals of the Ternary Complex Containing a T-box Stem I RNA, its Cognate tRNAGly, and B. subtilis YbxF protein, treated by removing lithium sulfate and increasing PEG3350 concentration from 20% to 45% post crystallization
Descriptor: MAGNESIUM ION, Ribosome-associated protein L7Ae-like, T-box Stem I RNA, ...
Authors:Zhang, J, Ferre-D'Amare, A.R.
Deposit date:2014-07-11
Release date:2014-09-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.64 Å)
Cite:Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration.
Structure, 22, 2014
1JVI
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BU of 1jvi by Molmil
THE 2.2 ANGSTROM RESOLUTION STRUCTURE OF BACILLUS SUBTILIS LUXS/RIBOSILHOMOCYSTEINE COMPLEX
Descriptor: (2S)-2-amino-4-[[(2S,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methylsulfanyl]butanoic acid, 2-AMINO-4-MERCAPTO-BUTYRIC ACID, Autoinducer-2 production protein luxS, ...
Authors:Ruzheinikov, S.N, Das, S.K, Sedelnikova, S.E, Hartley, A, Foster, S.J, Horsburgh, M.J, Cox, A.G, McCleod, C.W, Mekhalfia, A, Blackburn, G.M, Rice, D.W, Baker, P.J.
Deposit date:2001-08-30
Release date:2001-10-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The 1.2 A structure of a novel quorum-sensing protein, Bacillus subtilis LuxS
J.Mol.Biol., 313, 2001
6V1G
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BU of 6v1g by Molmil
Genome-containing AAVrh.10
Descriptor: Capsid protein VP1, DNA (5'-D(*CP*A)-3')
Authors:Mietzsch, M, Agbandje-McKenna, M.
Deposit date:2019-11-20
Release date:2019-12-11
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Comparative Analysis of the Capsid Structures of AAVrh.10, AAVrh.39, and AAV8.
J.Virol., 94, 2020
2VOE
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BU of 2voe by Molmil
Crystal structure of Rv2780 from M. tuberculosis H37Rv
Descriptor: ALANINE DEHYDROGENASE
Authors:Tripathi, S.M, Ramachandran, R.
Deposit date:2008-02-17
Release date:2008-03-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structures of the Mycobacterium Tuberculosis Secretory Antigen Alanine Dehydrogenase (Rv2780) in Apo and Ternary Complex Forms Captures "Open" and "Closed" Enzyme Conformations.
Proteins, 72, 2008
6TKV
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BU of 6tkv by Molmil
Crystal structure of the human FUT8 in complex with GDP and a biantennary complex N-glycan
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-(1,6)-fucosyltransferase, GLYCEROL, ...
Authors:Garcia-Garcia, A, Ceballos-Laita, L, Serna, L, Artschwager, R, Reichardt, N.C, Corzana, F, Hurtado-Guerrero, R.
Deposit date:2019-11-29
Release date:2020-01-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis for substrate specificity and catalysis of alpha 1,6-fucosyltransferase.
Nat Commun, 11, 2020

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