4ZCG
Crystal Structure of human GGT1 in complex with Glutamate (with all atoms of glutamate)
Summary for 4ZCG
Entry DOI | 10.2210/pdb4zcg/pdb |
Descriptor | Gamma-glutamyltranspeptidase 1 heavy chain, Gamma-glutamyltranspeptidase 1 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | ntn-hydrolase family, glycoprotein, n- glycosylation, cell surface, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 60116.38 |
Authors | Terzyan, S.,Hanigan, M. (deposition date: 2015-04-15, release date: 2015-06-03, Last modification date: 2023-09-27) |
Primary citation | Terzyan, S.S.,Burgett, A.W.,Heroux, A.,Smith, C.A.,Mooers, B.H.,Hanigan, M.H. Human gamma-Glutamyl Transpeptidase 1: STRUCTURES OF THE FREE ENZYME, INHIBITOR-BOUND TETRAHEDRAL TRANSITION STATES, AND GLUTAMATE-BOUND ENZYME REVEAL NOVEL MOVEMENT WITHIN THE ACTIVE SITE DURING CATALYSIS. J.Biol.Chem., 290:17576-17586, 2015 Cited by PubMed: 26013825DOI: 10.1074/jbc.M115.659680 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.22 Å) |
Structure validation
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