1NR8

The crystal structure of a D-Lysine-based chiral PNA-DNA duplex

Summary for 1NR8

• Entry DOI: 10.2210/pdb1nr8/pdb
• Related: 1PDT 1PUP
• Descriptor: 5'-D(P*AP*GP*TP*GP*AP*TP*CP*TP*AP*C)-3', H-((GPN)*(TPN)*(APN)*(GPN)*(A66)*(T66)*(C66)*(APN)*(CPN)*(TPN))-NH2, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: chiral peptide nucleic acid, double stranded helix, p-form, dna-peptide nucleic acid complex, dna/peptide nucleic acid
• Total number of polymer chains: 2
• Total formula weight: 5951.37

Authors

Menchise, V.,De Simone, G.,Tedeschi, T.,Corradini, R.,Sforza, S.,Marchelli, R.,Capasso, D.,Saviano, M.,Pedone, C. (deposition date: 2003-01-24, release date: 2003-10-28, Last modification date: 2023-11-15)

• Primary citation: Menchise, V.,De Simone, G.,Tedeschi, T.,Corradini, R.,Sforza, S.,Marchelli, R.,Capasso, D.,Saviano, M.,Pedone, C.; Insights into peptide nucleic acid (PNA) structural features: The crystal structure of a D-lysine-based chiral PNA-DNA duplex; Proc.Natl.Acad.Sci.USA, 100:12021-12026, 2003; PubMed: 14512516; DOI: 10.1073/pnas.2034746100

Experimental method

X-RAY DIFFRACTION (1.66 Å)