8QTJ
 
 | | Crystal structure of Cbl-b in complex with an allosteric inhibitor (compound 30) | | Descriptor: | 3-[3-[3-methyl-1-(4-methyl-1,2,4-triazol-3-yl)cyclobutyl]phenyl]-1-[(1~{R})-1-(1-methylpyrazol-4-yl)ethyl]-5-(trifluoromethyl)pyridin-2-one, E3 ubiquitin-protein ligase CBL-B, SODIUM ION, ... | | Authors: | Schimpl, M. | | Deposit date: | 2023-10-12 | | Release date: | 2024-01-10 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.523 Å) | | Cite: | Discovery, Optimization, and Biological Evaluation of Arylpyridones as Cbl-b Inhibitors.
J.Med.Chem., 67, 2024
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8WQ5
 | | Crystal structure of the C-terminal RRM domain of an RBP in complex with ssDNA | | Descriptor: | DNA (5'-D(*GP*AP*CP*GP*CP*AP*G)-3'), GLYCEROL, RNA-binding protein 45 | | Authors: | Chen, X, Yang, Z, Chen, X, Wei, Q, Guo, S, Jiang, M, Wang, M. | | Deposit date: | 2023-10-11 | | Release date: | 2024-08-21 | | Last modified: | 2024-09-18 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structural basis for RNA recognition by the C-terminal RRM domain of human RBM45.
J.Biol.Chem., 300, 2024
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8UIN
 | | Structure of the C3bBb-albicin complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Albicin, ... | | Authors: | Andersen, J.F, Lei, H. | | Deposit date: | 2023-10-10 | | Release date: | 2024-05-08 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.86 Å) | | Cite: | Mechanism of complement inhibition by a mosquito protein revealed through cryo-EM.
Commun Biol, 7, 2024
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8UI8
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8WPU
 | | Human calcium-sensing receptor(CaSR) bound to cinacalcet in complex with Gq protein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Ling, S.L, Meng, X.Y, Tian, C.L. | | Deposit date: | 2023-10-10 | | Release date: | 2023-11-22 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural insights into asymmetric activation of the calcium-sensing receptor-G q complex.
Cell Res., 34, 2024
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8WPG
 | | Human calcium-sensing receptor bound with cinacalcet in detergent | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Ling, S.L, Meng, X.Y, Tian, C.L. | | Deposit date: | 2023-10-10 | | Release date: | 2023-11-22 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural insights into asymmetric activation of the calcium-sensing receptor-G q complex.
Cell Res., 34, 2024
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8WPZ
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8WQ3
 | | Crystal structure of the C-terminal RRM domain of an RBP | | Descriptor: | CHLORIDE ION, RNA-binding protein 45 | | Authors: | Chen, X, Jiang, M, Yang, Z, Chen, X, Wei, Q, Guo, S, Wang, M. | | Deposit date: | 2023-10-10 | | Release date: | 2024-08-21 | | Last modified: | 2024-09-18 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | Structural basis for RNA recognition by the C-terminal RRM domain of human RBM45.
J.Biol.Chem., 300, 2024
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8UI7
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8UI9
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8UII
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8WP9
 | | Small-heat shock protein from Methanocaldococcus jannaschii, Hsp16.5 | | Descriptor: | Small heat shock protein HSP16.5 | | Authors: | Lee, J, Ryu, B, Kim, T, Kim, K.K. | | Deposit date: | 2023-10-09 | | Release date: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (2.49 Å) | | Cite: | Cryo-EM structure of a 16.5-kDa small heat-shock protein from Methanocaldococcus jannaschii.
Int.J.Biol.Macromol., 258, 2024
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8UHI
 | | Structure of the far-red light-absorbing allophycocyanin core expressed during FaRLiP | | Descriptor: | MAGNESIUM ION, RIBULOSE-1,5-DIPHOSPHATE, Ribulose bisphosphate carboxylase large subunit, ... | | Authors: | Gisriel, C.J, Bryant, D.A, Brudvig, G.W, Shen, G. | | Deposit date: | 2023-10-09 | | Release date: | 2024-01-03 | | Last modified: | 2024-01-31 | | Method: | ELECTRON MICROSCOPY (2.35 Å) | | Cite: | Structure of the antenna complex expressed during far-red light photoacclimation in Synechococcus sp. PCC 7335.
J.Biol.Chem., 300, 2023
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8QRN
 | | mt-SSU in GTPBP8 knock-out cells, state 4 | | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | | Authors: | Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M. | | Deposit date: | 2023-10-09 | | Release date: | 2024-06-26 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | GTPBP8 plays a role in mitoribosome formation in human mitochondria.
Nat Commun, 15, 2024
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8UI0
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8UHG
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8UHA
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8WP0
 | | Structure of the Arabidopsis E529Q/E1174Q ABCB19 in the ATP bound state | | Descriptor: | ABC transporter B family member 19, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | | Authors: | Ying, W, Wei, H, Liu, X, Sun, L. | | Deposit date: | 2023-10-08 | | Release date: | 2024-03-13 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export.
Science, 383, 2024
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8UHB
 | | Cryo-EM Structure of the Ro5256390-bound hTA1-Gs heterotrimer signaling complex | | Descriptor: | (2R,4S)-4-[(2S)-2-phenylbutyl]-1,3-oxazolidin-2-amine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Zilberg, G, Warren, A.L, Parpounas, A.K, Wacker, D. | | Deposit date: | 2023-10-08 | | Release date: | 2024-01-10 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Molecular basis of human trace amine-associated receptor 1 activation.
Nat Commun, 15, 2024
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8WP1
 | | Cryo-EM structure of SUCR1 in complex with cis-epoxysuccinic acid and Gi proteins | | Descriptor: | (2R,3S)-oxirane-2,3-dicarboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Liu, A, Ye, R.D. | | Deposit date: | 2023-10-08 | | Release date: | 2024-09-11 | | Last modified: | 2024-09-18 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Structural insights into ligand recognition and activation of the succinate receptor SUCNR1.
Cell Rep, 43, 2024
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8UHD
 | | Structure of paused transcription complex Pol II-DSIF-NELF - post-translocated | | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ... | | Authors: | Su, B.G, Vos, S.M. | | Deposit date: | 2023-10-08 | | Release date: | 2024-03-20 | | Last modified: | 2024-09-11 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing.
Mol.Cell, 84, 2024
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8WOM
 | | Structure of the wild-type Arabidopsis ABCB19 in the brassinolide-bound state | | Descriptor: | ABC transporter B family member 19, Brassinolide | | Authors: | Ying, W, Wei, H, Liu, X, Sun, L. | | Deposit date: | 2023-10-07 | | Release date: | 2024-03-13 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export.
Science, 383, 2024
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8WOI
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8WOO
 | | Structure of the wild-type Arabidopsis ABCB19 in the brassinolide and AMP-PNP bound state | | Descriptor: | ABC transporter B family member 19, Brassinolide, MAGNESIUM ION, ... | | Authors: | Ying, W, Wei, H, Liu, X, Sun, L. | | Deposit date: | 2023-10-07 | | Release date: | 2024-03-13 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export.
Science, 383, 2024
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8UH7
 | | Structure of T4 Bacteriophage clamp loader bound to the T4 clamp, primer-template DNA, and ATP analog | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Primer DNA strand, ... | | Authors: | Gee, C.L, Marcus, K, Kelch, B.A, Makino, D.L. | | Deposit date: | 2023-10-07 | | Release date: | 2023-12-13 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.628 Å) | | Cite: | Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM.
Nat.Struct.Mol.Biol., 31, 2024
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