3N06
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![BU of 3n06 by Molmil](/molmil-images/mine/3n06) | A mutant human Prolactin receptor antagonist H27A in complex with the extracellular domain of the human prolactin receptor | Descriptor: | CHLORIDE ION, Prolactin, Prolactin receptor, ... | Authors: | Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E. | Deposit date: | 2010-05-13 | Release date: | 2010-09-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation. J.Biol.Chem., 285, 2010
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8AC8
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![BU of 8ac8 by Molmil](/molmil-images/mine/8ac8) | The nucleoprotein complex of Rep protein with DUE ssDNA | Descriptor: | DNA (5'-D(*AP*TP*TP*TP*TP*TP*AP*TP*A)-3'), Replication initiation protein | Authors: | Nowacka, M, Wegrzyn, K, Oliwa, M, Konieczny, I. | Deposit date: | 2022-07-05 | Release date: | 2023-09-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Rep protein accommodates together dsDNA and ssDNA which enables a loop-back mechanism to plasmid DNA replication initiation. Nucleic Acids Res., 51, 2023
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8JAY
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![BU of 8jay by Molmil](/molmil-images/mine/8jay) | CrtSPARTA Octamer bound with guide-target | Descriptor: | DNA (25-MER), MAGNESIUM ION, Piwi domain-containing protein, ... | Authors: | Guo, L.J, Huang, P.P, Li, Z.X, Xiao, Y.B, Chen, M.R. | Deposit date: | 2023-05-07 | Release date: | 2024-03-20 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system. Nat.Chem.Biol., 20, 2024
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6NXX
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![BU of 6nxx by Molmil](/molmil-images/mine/6nxx) | Crystal structure of Arabidopsis thaliana cytosolic triosephosphate isomerase C218K mutant | Descriptor: | SODIUM ION, Triosephosphate isomerase, cytosolic | Authors: | Jimenez-Sandoval, P, Fuentes-Pascacio, A, Diaz-Quezada, C, Torres-Larios, A, Brieba, L.G. | Deposit date: | 2019-02-10 | Release date: | 2020-02-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structural basis for the modulation of plant cytosolic triosephosphate isomerase activity by mimicry of redox-based modifications. Plant J., 99, 2019
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4J0B
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![BU of 4j0b by Molmil](/molmil-images/mine/4j0b) | Structure of mitochondrial Hsp90 (TRAP1) with ADP-BeF3 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, COBALT (II) ION, ... | Authors: | Partridge, J.R, Lavery, L.A, Agard, D.A. | Deposit date: | 2013-01-30 | Release date: | 2014-01-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.352 Å) | Cite: | Structural asymmetry in the closed state of mitochondrial Hsp90 (TRAP1) supports a two-step ATP hydrolysis mechanism. Mol.Cell, 53, 2014
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7UD6
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![BU of 7ud6 by Molmil](/molmil-images/mine/7ud6) | |
6CQ8
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![BU of 6cq8 by Molmil](/molmil-images/mine/6cq8) | K2P2.1(TREK-1):ML335 complex | Descriptor: | CADMIUM ION, HEXADECANE, N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)PALMITAMIDE, ... | Authors: | Lolicato, M, Minor, D.L. | Deposit date: | 2018-03-14 | Release date: | 2018-03-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site. Nature, 547, 2017
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6CQD
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![BU of 6cqd by Molmil](/molmil-images/mine/6cqd) | Crystal structure of HPK1 in complex with ATP analogue (AMPPNP) | Descriptor: | MAGNESIUM ION, Mitogen-activated protein kinase kinase kinase kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Wu, P, Lehoux, I, Franke, Y, Mortara, K, Wang, W. | Deposit date: | 2018-03-14 | Release date: | 2018-12-19 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Hematopoietic Progenitor Kinase-1 Structure in a Domain-Swapped Dimer. Structure, 27, 2019
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3NQJ
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![BU of 3nqj by Molmil](/molmil-images/mine/3nqj) | Crystal structure of (CENP-A/H4)2 heterotetramer | Descriptor: | Histone H3-like centromeric protein A, Histone H4, PHOSPHATE ION | Authors: | Sekulic, N, Black, B.E. | Deposit date: | 2010-06-29 | Release date: | 2010-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structure of (CENP-A-H4)(2) reveals physical features that mark centromeres. Nature, 467, 2010
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8JES
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![BU of 8jes by Molmil](/molmil-images/mine/8jes) | Cryo-EM structure of DltB homo-tetramer | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, DIACYL GLYCEROL, DODECYL-BETA-D-MALTOSIDE, ... | Authors: | Zhang, P, Liu, Z. | Deposit date: | 2023-05-16 | Release date: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Structural insights into the transporting and catalyzing mechanism of DltB in LTA D-alanylation. Nat Commun, 15, 2024
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8JF2
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![BU of 8jf2 by Molmil](/molmil-images/mine/8jf2) | Cryo-EM structure of tetrameric DltB/DltC complex | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, D-alanyl carrier protein, DIACYL GLYCEROL, ... | Authors: | Zhang, P, Liu, Z. | Deposit date: | 2023-05-17 | Release date: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural insights into the transporting and catalyzing mechanism of DltB in LTA D-alanylation. Nat Commun, 15, 2024
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4IVG
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![BU of 4ivg by Molmil](/molmil-images/mine/4ivg) | Crystal structure of mitochondrial Hsp90 (TRAP1) NTD-Middle domain dimer with AMPPNP | Descriptor: | MAGNESIUM ION, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Partridge, J.R, Lavery, L.A, Agard, D.A. | Deposit date: | 2013-01-22 | Release date: | 2014-01-22 | Last modified: | 2014-08-27 | Method: | X-RAY DIFFRACTION (1.749 Å) | Cite: | Structural asymmetry in the closed state of mitochondrial Hsp90 (TRAP1) supports a two-step ATP hydrolysis mechanism. Mol.Cell, 53, 2014
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6BJ8
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![BU of 6bj8 by Molmil](/molmil-images/mine/6bj8) | TCR55 in complex with Pep20/HLA-B35 | Descriptor: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | Authors: | Jude, K.M, Sibener, L.V, Yang, X, Garcia, K.C. | Deposit date: | 2017-11-05 | Release date: | 2018-07-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding. Cell, 174, 2018
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6NXQ
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![BU of 6nxq by Molmil](/molmil-images/mine/6nxq) | Crystal structure of Arabidopsis thaliana cytosolic triosephosphate isomerase C13A mutant | Descriptor: | SODIUM ION, Triosephosphate isomerase, cytosolic | Authors: | Jimenez-Sandoval, P, Diaz-Quezada, C, Torres-Larios, A, Brieba, L.G. | Deposit date: | 2019-02-09 | Release date: | 2020-02-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structural basis for the modulation of plant cytosolic triosephosphate isomerase activity by mimicry of redox-based modifications. Plant J., 99, 2019
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8JEM
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![BU of 8jem by Molmil](/molmil-images/mine/8jem) | DltB tetramer in complex with inhibitor m-AMSA | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, DIACYL GLYCEROL, DODECYL-BETA-D-MALTOSIDE, ... | Authors: | Zhang, P, Liu, Z. | Deposit date: | 2023-05-16 | Release date: | 2024-05-15 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Structural insights into the transporting and catalyzing mechanism of DltB in LTA D-alanylation. Nat Commun, 15, 2024
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6NXW
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![BU of 6nxw by Molmil](/molmil-images/mine/6nxw) | Crystal structure of Arabidopsis thaliana cytosolic triosephosphate isomerase C218S mutant | Descriptor: | Triosephosphate isomerase, cytosolic | Authors: | Jimenez-Sandoval, P, Diaz-Quezada, C, Torres-Larios, A, Brieba, L.G. | Deposit date: | 2019-02-10 | Release date: | 2020-02-19 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis for the modulation of plant cytosolic triosephosphate isomerase activity by mimicry of redox-based modifications. Plant J., 99, 2019
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6NXR
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![BU of 6nxr by Molmil](/molmil-images/mine/6nxr) | Crystal structure of Arabidopsis thaliana cytosolic triosephosphate isomerase C13D mutant | Descriptor: | GLYCEROL, SODIUM ION, Triosephosphate isomerase, ... | Authors: | Jimenez-Sandoval, P, Diaz-Quezada, C, Torres-Larios, A, Brieba, L.G. | Deposit date: | 2019-02-09 | Release date: | 2020-02-19 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structural basis for the modulation of plant cytosolic triosephosphate isomerase activity by mimicry of redox-based modifications. Plant J., 99, 2019
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6NXY
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![BU of 6nxy by Molmil](/molmil-images/mine/6nxy) | Crystal structure of Arabidopsis thaliana cytosolic triosephosphate isomerase C218D mutant | Descriptor: | SODIUM ION, Triosephosphate isomerase, cytosolic | Authors: | Jimenez-Sandoval, P, Diaz-Quezada, C, Torres-Larios, A, Brieba, L.G. | Deposit date: | 2019-02-10 | Release date: | 2020-02-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Structural basis for the modulation of plant cytosolic triosephosphate isomerase activity by mimicry of redox-based modifications. Plant J., 99, 2019
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5JVK
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![BU of 5jvk by Molmil](/molmil-images/mine/5jvk) | Structural insights into a family 39 glycoside hydrolase from the gut symbiont Bacteroides cellulosilyticus WH2. | Descriptor: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, GLYCEROL, SULFATE ION, ... | Authors: | Ali-Ahmad, A, Garron, M.L, Zamboni, V, Lenfant, N, Bourne, Y, Vincent, F. | Deposit date: | 2016-05-11 | Release date: | 2016-12-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural insights into a family 39 glycoside hydrolase from the gut symbiont Bacteroides cellulosilyticus WH2. J. Struct. Biol., 197, 2017
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6BVZ
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![BU of 6bvz by Molmil](/molmil-images/mine/6bvz) | Importin alpha 3 in cargo free state | Descriptor: | Importin subunit alpha-3 | Authors: | Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | Deposit date: | 2017-12-14 | Release date: | 2018-07-04 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses. Nat Commun, 9, 2018
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6CQE
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![BU of 6cqe by Molmil](/molmil-images/mine/6cqe) | Crystal structure of HPK1 kinase domain S171A mutant | Descriptor: | Mitogen-activated protein kinase kinase kinase kinase 1 | Authors: | Wu, P, Lehoux, I, Mortara, K, Franke, Y, Wang, W. | Deposit date: | 2018-03-15 | Release date: | 2018-12-19 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.886 Å) | Cite: | Hematopoietic Progenitor Kinase-1 Structure in a Domain-Swapped Dimer. Structure, 27, 2019
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8BVB
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![BU of 8bvb by Molmil](/molmil-images/mine/8bvb) | |
4IYN
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![BU of 4iyn by Molmil](/molmil-images/mine/4iyn) | Structure of mitochondrial Hsp90 (TRAP1) with ADP-ALF4- | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, COBALT (II) ION, MAGNESIUM ION, ... | Authors: | Partridge, J.R, Lavery, L.A, Agard, D.A. | Deposit date: | 2013-01-28 | Release date: | 2014-01-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.312 Å) | Cite: | Structural asymmetry in the closed state of mitochondrial Hsp90 (TRAP1) supports a two-step ATP hydrolysis mechanism. Mol.Cell, 53, 2014
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2AZY
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![BU of 2azy by Molmil](/molmil-images/mine/2azy) | Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Cholate | Descriptor: | CALCIUM ION, CHOLIC ACID, Phospholipase A2, ... | Authors: | Pan, Y.H, Bahnson, B.J, Jain, M.K. | Deposit date: | 2005-09-12 | Release date: | 2006-11-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for bile salt inhibition of pancreatic phospholipase A2. J.Mol.Biol., 369, 2007
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7W80
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![BU of 7w80 by Molmil](/molmil-images/mine/7w80) | Crystal Structure of the Heterodimeric HIF-2 in Complex with Antagonist Belzutifan | Descriptor: | 3-{[(1S,2S,3R)-2,3-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl]oxy}-5-fluorobenzonitrile, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 | Authors: | Ren, X, Diao, X, Zhuang, J, Wu, D. | Deposit date: | 2021-12-07 | Release date: | 2022-09-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.754 Å) | Cite: | Structural basis for the allosteric inhibition of hypoxia-inducible factor (HIF)-2 by belzutifan. Mol.Pharmacol., 2022
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