6CQD
Crystal structure of HPK1 in complex with ATP analogue (AMPPNP)
Summary for 6CQD
Entry DOI | 10.2210/pdb6cqd/pdb |
Descriptor | Mitogen-activated protein kinase kinase kinase kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | protein kinase, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 67498.21 |
Authors | Wu, P.,Lehoux, I.,Franke, Y.,Mortara, K.,Wang, W. (deposition date: 2018-03-14, release date: 2018-12-19, Last modification date: 2024-03-13) |
Primary citation | Wu, P.,Sneeringer, C.J.,Pitts, K.E.,Day, E.S.,Chan, B.K.,Wei, B.,Lehoux, I.,Mortara, K.,Li, H.,Wu, J.,Franke, Y.,Moffat, J.G.,Grogan, J.L.,Heffron, T.P.,Wang, W. Hematopoietic Progenitor Kinase-1 Structure in a Domain-Swapped Dimer. Structure, 27:125-133.e4, 2019 Cited by PubMed: 30503777DOI: 10.1016/j.str.2018.10.025 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.12 Å) |
Structure validation
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