6CQE
Crystal structure of HPK1 kinase domain S171A mutant
Summary for 6CQE
| Entry DOI | 10.2210/pdb6cqe/pdb |
| Descriptor | Mitogen-activated protein kinase kinase kinase kinase 1 (2 entities in total) |
| Functional Keywords | protein kinase, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 65952.56 |
| Authors | Wu, P.,Lehoux, I.,Mortara, K.,Franke, Y.,Wang, W. (deposition date: 2018-03-15, release date: 2018-12-19, Last modification date: 2024-03-13) |
| Primary citation | Wu, P.,Sneeringer, C.J.,Pitts, K.E.,Day, E.S.,Chan, B.K.,Wei, B.,Lehoux, I.,Mortara, K.,Li, H.,Wu, J.,Franke, Y.,Moffat, J.G.,Grogan, J.L.,Heffron, T.P.,Wang, W. Hematopoietic Progenitor Kinase-1 Structure in a Domain-Swapped Dimer. Structure, 27:125-133.e4, 2019 Cited by PubMed: 30503777DOI: 10.1016/j.str.2018.10.025 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.886 Å) |
Structure validation
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