6CQE
Crystal structure of HPK1 kinase domain S171A mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Mitogen-activated protein kinase kinase kinase kinase 1 | polymer | 295 | 32976.3 | 2 | UniProt (Q92918) Pfam (PF00069) | Homo sapiens (Human) | HKP1, Hematopoietic progenitor kinase, MAPK/ERK kinase kinase kinase 1, MEKKK 1 |
| 2 | C, D (A, B) | water | water | 18.0 | 376 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 293 (UniProt: Q92918)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Ala 171 | Ser 171 | engineered mutation |
| Asn 294 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65952.6 | |
| All* | Total formula weight | 65952.6 |
