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5GXG
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BU of 5gxg by Molmil
High-resolution crystal structure of the electron transfer complex of cytochrome p450cam with putidaredoxin
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Camphor 5-monooxygenase, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Kikui, Y, Hiruma, Y, Ubbink, M, Nojiri, M.
Deposit date:2016-09-17
Release date:2017-01-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Identification of productive and futile encounters in an electron transfer protein complex
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3JPN
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BU of 3jpn by Molmil
Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-dichloro methylene triphosphate
Descriptor: 2'-deoxy-5'-O-[(S)-{[(R)-[dichloro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]guanosine, 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ...
Authors:Batra, V.K, Upton, J, Kashmerov, B, Beard, W.A, Wilson, S.H, Goodman, M.F, McKenna, C.E.
Deposit date:2009-09-04
Release date:2010-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Halogenated beta,gamma-Methylene- and Ethylidene-dGTP-DNA Ternary Complexes with DNA Polymerase beta: Structural Evidence for Stereospecific Binding of the Fluoromethylene Analogues.
J.Am.Chem.Soc., 132, 2010
3K80
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BU of 3k80 by Molmil
Structure of essential protein from Trypanosoma brucei
Descriptor: Antibody, MP18 RNA editing complex protein
Authors:Wu, M.
Deposit date:2009-10-13
Release date:2010-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of a key interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies.
J.Struct.Biol., 174, 2011
8WKL
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BU of 8wkl by Molmil
Rauvolfia serpentina strictosidine synthase (RsSTR) in complex with a non-reactive tryptamine substitute crystallized in P1211 space group
Descriptor: 2-(2-methyl-1H-indol-3-yl)ethanamine, DI(HYDROXYETHYL)ETHER, Strictosidine synthase
Authors:Nitin, K, Rajakumara, E.
Deposit date:2023-09-28
Release date:2024-02-28
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Proxy-approach in understanding the bisubstrate activity of strictosidine synthases.
Int.J.Biol.Macromol., 262, 2024
3JPS
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BU of 3jps by Molmil
Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-fluoro methyl methylene triphosphate
Descriptor: 2'-deoxy-5'-O-[(S)-{[(S)-[(1R)-1-fluoro-1-phosphonoethyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]guanosine, 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ...
Authors:Batra, V.K, Upton, J, Kashmerov, B, Beard, W.A, Wilson, S.H, Goodman, M.F, McKenna, C.E.
Deposit date:2009-09-04
Release date:2010-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Halogenated beta,gamma-Methylene- and Ethylidene-dGTP-DNA Ternary Complexes with DNA Polymerase beta: Structural Evidence for Stereospecific Binding of the Fluoromethylene Analogues.
J.Am.Chem.Soc., 132, 2010
8VM2
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BU of 8vm2 by Molmil
Crystal Structure of NRAS Q61K bound to GTP
Descriptor: GTPase NRas, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Gebregiworgis, T, Chan, J.Y.L, Kuntz, D.A, Prive, G.G, Marshall, C.B, Ikura, M.
Deposit date:2024-01-12
Release date:2024-05-01
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal structure of NRAS Q61K with a ligand-induced pocket near switch II.
Eur J Cell Biol, 103, 2024
8V7W
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BU of 8v7w by Molmil
Room-temperature X-ray structure of SARS-CoV-2 main protease catalytic domain C145A precursor, residues nsp4(-6)-1-199-6H
Descriptor: Replicase polyprotein 1ab
Authors:Kovalevsky, A, Coates, L.
Deposit date:2023-12-04
Release date:2024-05-29
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Visualizing the Active Site Oxyanion Loop Transition Upon Ensitrelvir Binding and Transient Dimerization of SARS-CoV-2 Main Protease.
J.Mol.Biol., 436, 2024
8V7T
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BU of 8v7t by Molmil
Room-temperature X-ray structure of SARS-CoV-2 main protease catalytic domain (residues 1-199)
Descriptor: Non-structural protein 7
Authors:Kovalevsky, A, Coates, L.
Deposit date:2023-12-04
Release date:2024-05-29
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Visualizing the Active Site Oxyanion Loop Transition Upon Ensitrelvir Binding and Transient Dimerization of SARS-CoV-2 Main Protease.
J.Mol.Biol., 436, 2024
8VF8
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BU of 8vf8 by Molmil
Binary DNA Polymerase Beta bound to DNA containing primer terminal dC base-paired with FapydG
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*CP*(FAP)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Oden, P.N, Ryan, B.J, Freudenthal, B.D.
Deposit date:2023-12-21
Release date:2024-05-08
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta.
Nucleic Acids Res., 52, 2024
8VFH
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BU of 8vfh by Molmil
Ternary DNA Polymerase Beta bound to DNA containing primer terminal FapydG base-paired with a dC
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(FAP))-3'), ...
Authors:Oden, P.N, Ryan, B.J, Freudenthal, B.D.
Deposit date:2023-12-21
Release date:2024-05-08
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta.
Nucleic Acids Res., 52, 2024
8VFA
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BU of 8vfa by Molmil
Ternary DNA Polymerase Beta bound to DNA containing primer terminal dC base-paired with FapydG
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*CP*(FAP)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Oden, P.N, Ryan, B.J, Freudenthal, B.D.
Deposit date:2023-12-21
Release date:2024-05-08
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta.
Nucleic Acids Res., 52, 2024
8V8G
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BU of 8v8g by Molmil
Room-temperature X-ray structure of SARS-CoV-2 main protease catalytic domain (residues 1-196) in complex with ensitrelvir (ESV)
Descriptor: 3C-like proteinase nsp5, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione
Authors:Kovalevsky, A, Coates, L.
Deposit date:2023-12-05
Release date:2024-05-29
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Visualizing the Active Site Oxyanion Loop Transition Upon Ensitrelvir Binding and Transient Dimerization of SARS-CoV-2 Main Protease.
J.Mol.Biol., 436, 2024
8VF9
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BU of 8vf9 by Molmil
Binary DNA Polymerase Beta bound to DNA containing primer terminal dA base-paired with FapydG
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*CP*(FAP)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Oden, P.N, Ryan, B.J, Freudenthal, B.D.
Deposit date:2023-12-21
Release date:2024-05-08
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta.
Nucleic Acids Res., 52, 2024
8VFG
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BU of 8vfg by Molmil
Binary DNA Polymerase Beta bound to DNA containing primer terminal FapydG base-paired with a dC
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(FAP))-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Oden, P.N, Ryan, B.J, Freudenthal, B.D.
Deposit date:2023-12-21
Release date:2024-05-08
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta.
Nucleic Acids Res., 52, 2024
5EOL
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BU of 5eol by Molmil
Crystal structure of human Pim-1 kinase in complex with a macrocyclic quinoxaline-pyrrolodihydropiperidinone inhibitor
Descriptor: GLYCEROL, Serine/threonine-protein kinase pim-1, macrocyclic quinoxaline-pyrrolodihydropiperidinone
Authors:Mohr, C.
Deposit date:2015-11-10
Release date:2016-05-04
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery and Optimization of Macrocyclic Quinoxaline-pyrrolo-dihydropiperidinones as Potent Pim-1/2 Kinase Inhibitors.
Acs Med.Chem.Lett., 7, 2016
8W0T
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BU of 8w0t by Molmil
Human LCAD
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Long-chain specific acyl-CoA dehydrogenase, mitochondrial
Authors:Xia, C, Kim, J.J.P.
Deposit date:2024-02-14
Release date:2024-06-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for expanded substrate specificities of human long chain acyl-CoA dehydrogenase and related acyl-CoA dehydrogenases.
Sci Rep, 14, 2024
8W0U
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BU of 8w0u by Molmil
Human LCAD complexed with Acetoacetyl Coenzyme A
Descriptor: ACETOACETYL-COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE, Long-chain specific acyl-CoA dehydrogenase, ...
Authors:Xia, C, Kim, J.J.P.
Deposit date:2024-02-14
Release date:2024-06-19
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for expanded substrate specificities of human long chain acyl-CoA dehydrogenase and related acyl-CoA dehydrogenases.
Sci Rep, 14, 2024
8VFF
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BU of 8vff by Molmil
Binary DNA Polymerase Beta bound to DNA containing primer terminal FapydG base-paired with a dA
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(FAP))-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Oden, P.N, Ryan, B.J, Freudenthal, B.D.
Deposit date:2023-12-21
Release date:2024-05-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta.
Nucleic Acids Res., 52, 2024
8VFB
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BU of 8vfb by Molmil
Ternary DNA Polymerase Beta bound to DNA containing primer terminal dA base-paired with FapydG
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*CP*(FAP)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Oden, P.N, Ryan, B.J, Freudenthal, B.D.
Deposit date:2023-12-21
Release date:2024-05-08
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta.
Nucleic Acids Res., 52, 2024
8VFC
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BU of 8vfc by Molmil
Binary DNA Polymerase Beta bound to DNA containing primer terminal T base-paired with FapydG
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*(FAP)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Oden, P.N, Ryan, B.J, Freudenthal, B.D.
Deposit date:2023-12-21
Release date:2024-05-08
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta.
Nucleic Acids Res., 52, 2024
8VFE
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BU of 8vfe by Molmil
Binary DNA Polymerase Beta bound to DNA containing primer terminal FapydG base-paired with a T
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(FAP))-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Oden, P.N, Ryan, B.J, Freudenthal, B.D.
Deposit date:2023-12-21
Release date:2024-05-08
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta.
Nucleic Acids Res., 52, 2024
8VFD
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BU of 8vfd by Molmil
Ternary DNA Polymerase Beta bound to DNA containing template FapydG incoming TTP analog
Descriptor: 1-{2-deoxy-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]-beta-D-threo-pentofuranosyl}-5-methylpyrimidine-2,4(1H,3H)-dione, DNA (5'-D(*CP*CP*GP*AP*CP*(FAP)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
Authors:Oden, P.N, Ryan, B.J, Freudenthal, B.D.
Deposit date:2023-12-21
Release date:2024-05-08
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta.
Nucleic Acids Res., 52, 2024
8VFJ
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BU of 8vfj by Molmil
Polymerase Beta Host Guest Complex Containing FapydG base paired with TMP
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*(FAP)P*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*TP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Oden, P.N, Ryan, B.J, Freudenthal, B.D.
Deposit date:2023-12-21
Release date:2024-05-08
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta.
Nucleic Acids Res., 52, 2024
1AYX
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BU of 1ayx by Molmil
CRYSTAL STRUCTURE OF GLUCOAMYLASE FROM SACCHAROMYCOPSIS FIBULIGERA AT 1.7 ANGSTROMS
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLUCOAMYLASE
Authors:Sevcik, J, Hostinova, E, Gasperik, J, Solovicova, A, Wilson, K.S, Dauter, Z.
Deposit date:1997-11-12
Release date:1998-05-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of glucoamylase from Saccharomycopsis fibuligera at 1.7 A resolution.
Acta Crystallogr.,Sect.D, 54, 1998
3HW8
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BU of 3hw8 by Molmil
ternary complex of DNA polymerase lambda of a two nucleotide gapped DNA substrate with a C in the scrunch site
Descriptor: 1,2-ETHANEDIOL, 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*AP*GP*TP*AP*T)-3', ...
Authors:Garcia-Diaz, M, Bebenek, K, Larrea, A.A, Havener, J.M, Perera, L, Krahn, J.M, Pedersen, L.C, Ramsden, D.A, Kunkel, T.A.
Deposit date:2009-06-17
Release date:2009-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Scrunching Durning DNA Repair Synthesis
To be Published

223790

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