8W0U

Human LCAD complexed with Acetoacetyl Coenzyme A

Summary for 8W0U

• Entry DOI: 10.2210/pdb8w0u/pdb
• Related: 8W0T
• Descriptor: Long-chain specific acyl-CoA dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ACETOACETYL-COENZYME A, ... (4 entities in total)
• Functional Keywords: fatty acid beta-oxidation, lcad, flavoprotein, cholesterol metabolism
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 182824.40

Authors

Xia, C.,Kim, J.J.P. (deposition date: 2024-02-14, release date: 2024-06-19)

• Primary citation: Narayanan, B.,Xia, C.,McAndrew, R.,Shen, A.L.,Kim, J.P.; Structural basis for expanded substrate specificities of human long chain acyl-CoA dehydrogenase and related acyl-CoA dehydrogenases.; Sci Rep, 14:12976-12976, 2024; PubMed: 38839792; DOI: 10.1038/s41598-024-63027-6

Experimental method

X-RAY DIFFRACTION (2.8 Å)