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5TJS
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BU of 5tjs by Molmil
Crystal structure of FBP aldolase from Toxoplasma gondii, native form
Descriptor: Fructose-bisphosphate aldolase, GLYCEROL
Authors:Heron, P.W, Sygusch, J.
Deposit date:2016-10-05
Release date:2017-10-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Isomer activation controls stereospecificity of class I fructose-1,6-bisphosphate aldolases.
J. Biol. Chem., 292, 2017
5TK3
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BU of 5tk3 by Molmil
Crystal structure of FBP aldolase from Toxoplasma gondii, burst-phase ternary complex
Descriptor: 1,3-DIHYDROXYACETONEPHOSPHATE, Fructose-bisphosphate aldolase, GLYCERALDEHYDE-3-PHOSPHATE, ...
Authors:Heron, P.W, Sygusch, J.
Deposit date:2016-10-06
Release date:2017-10-04
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Isomer activation controls stereospecificity of class I fructose-1,6-bisphosphate aldolases.
J. Biol. Chem., 292, 2017
5TKN
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BU of 5tkn by Molmil
Crystal structure of FBP aldolase from Toxoplasma gondii, Schiff base FBP complex
Descriptor: 1,6-di-O-phosphono-D-fructose, Fructose-bisphosphate aldolase
Authors:Heron, P.W, Sygusch, J.
Deposit date:2016-10-07
Release date:2017-10-04
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Isomer activation controls stereospecificity of class I fructose-1,6-bisphosphate aldolases.
J. Biol. Chem., 292, 2017
5TB5
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BU of 5tb5 by Molmil
Crystal structure of full-length farnesylated and methylated KRAS4b in complex with PDE-delta (crystal form I - with partially disordered hypervariable region)
Descriptor: 1,2-ETHANEDIOL, FARNESYL, GTPase KRas, ...
Authors:Dharmaiah, S, Tran, T.H, Simanshu, D.K.
Deposit date:2016-09-11
Release date:2016-11-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of recognition of farnesylated and methylated KRAS4b by PDE delta.
Proc.Natl.Acad.Sci.USA, 113, 2016
5TLW
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BU of 5tlw by Molmil
Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor 1-phosphate-benzene 4-bisphosphonate
Descriptor: Fructose-bisphosphate aldolase A, GLYCEROL, {[4-(phosphonooxy)phenyl]methylene}bis(phosphonic acid)
Authors:Heron, P.W, Sygusch, J.
Deposit date:2016-10-12
Release date:2017-10-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase.
J.Med.Chem., 61, 2018
5UWU
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BU of 5uwu by Molmil
Crystal Structure of SMAD4 NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: CHLORIDE ION, Exportin-1, GLYCEROL, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWQ
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BU of 5uwq by Molmil
Crystal Structure of CDC7 NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Cell division cycle 7-related protein kinase, Exportin-1, GLYCEROL, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.278 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWJ
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BU of 5uwj by Molmil
Crystal Structure of FMRP NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.221 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5QU6
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BU of 5qu6 by Molmil
Crystal Structure of swapped human Nck SH3.1 domain, 1.8A, triclinic
Descriptor: Cytoplasmic protein NCK1
Authors:Rudolph, M.G.
Deposit date:2019-12-13
Release date:2020-02-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.816 Å)
Cite:Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5UWR
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BU of 5uwr by Molmil
Crystal Structure of CDC7 NES Peptide (extended) in complex with CRM1-Ran-RanBP1
Descriptor: CHLORIDE ION, Cell division cycle 7-related protein kinase, Exportin-1, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWP
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BU of 5uwp by Molmil
Crystal Structure of mDia2 NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.054 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWO
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BU of 5uwo by Molmil
Crystal Structure of Engineered FMRP-1b NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Engineered FMRP-1b peptide, Exportin-1, GLYCEROL, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.347 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWH
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BU of 5uwh by Molmil
Crystal Structure of Paxillin NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWT
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BU of 5uwt by Molmil
Crystal Structure of Hxk2 Peptide in complex with CRM1 K579A mutant-Ran-RanBP1
Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.342 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5TKL
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BU of 5tkl by Molmil
Crystal structure of FBP aldolase from Toxoplasma gondii, condensation intermediate
Descriptor: 1,3-DIHYDROXYACETONEPHOSPHATE, 1,6-di-O-phosphono-D-fructose, Fructose-bisphosphate aldolase, ...
Authors:Heron, P.W, Sygusch, J.
Deposit date:2016-10-06
Release date:2017-10-04
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (1.751 Å)
Cite:Isomer activation controls stereospecificity of class I fructose-1,6-bisphosphate aldolases.
J. Biol. Chem., 292, 2017
5TLH
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BU of 5tlh by Molmil
Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor 2-naphthol 6-bisphosphonate
Descriptor: Fructose-bisphosphate aldolase A, GLYCEROL, METHYLENEDIPHOSPHONIC ACID, ...
Authors:Heron, P.W, Sygusch, J.
Deposit date:2016-10-11
Release date:2017-10-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.204 Å)
Cite:Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase.
J.Med.Chem., 61, 2018
5UWS
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BU of 5uws by Molmil
Crystal Structure of X11L2 NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Amyloid beta A4 precursor protein-binding family A member 3, Exportin-1,Exportin-1, GLYCEROL, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5TLE
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BU of 5tle by Molmil
Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor 2-phosphate-naphthalene 6-bisphosphonate
Descriptor: Fructose-bisphosphate aldolase A, GLYCEROL, {[6-(phosphonooxy)naphthalen-2-yl]methylene}bis(phosphonic acid)
Authors:Heron, P.W, Sygusch, J.
Deposit date:2016-10-11
Release date:2017-10-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.576 Å)
Cite:Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase.
J.Med.Chem., 61, 2018
5VEI
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BU of 5vei by Molmil
Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2
Descriptor: Sorbin and SH3 domain-containing protein 2, UNKNOWN ATOM OR ION
Authors:Liu, Y, Tempel, W, Huang, H, Gu, J, Liu, K, Sidhu, S.S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2017-04-04
Release date:2017-08-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2
To be Published
5UWW
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BU of 5uww by Molmil
Crystal Structure of DEAF1 Peptide in complex with CRM1 K579A mutant-Ran-RanBP1
Descriptor: Deformed epidermal autoregulatory factor 1 homolog, Exportin-1, GLYCEROL, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.152 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5U4U
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BU of 5u4u by Molmil
pseudoGTPase domain (pG1) of p190RhoGAP-A
Descriptor: MALONATE ION, MGC81300 protein, SODIUM ION
Authors:Stiegler, A.L, Boggon, T.J.
Deposit date:2016-12-06
Release date:2017-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:p190RhoGAP proteins contain pseudoGTPase domains.
Nat Commun, 8, 2017
5UWI
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BU of 5uwi by Molmil
Crystal Structure of HDAC5 NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.143 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5W1A
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BU of 5w1a by Molmil
The first X-ray crystal structure of an insect muscle myosin. Drosophila melanogaster, skeletal muscle myosin II, an embryonic isoform, subfragment-1
Descriptor: 1,2-ETHANEDIOL, CITRATE ANION, GLYCEROL, ...
Authors:Caldwell, J.T, Bernstein, S.I, Huxford, T.
Deposit date:2017-06-02
Release date:2018-06-06
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.227 Å)
Cite:X-ray crystallographic and molecular dynamic analyses of Drosophila melanogaster embryonic muscle myosin define domains responsible for isoform-specific properties.
J.Mol.Biol., 2019
2EYZ
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BU of 2eyz by Molmil
CT10-Regulated Kinase isoform II
Descriptor: v-crk sarcoma virus CT10 oncogene homolog isoform a
Authors:Kobashigawa, Y, Tanaka, S, Inagaki, F.
Deposit date:2005-11-10
Release date:2006-11-10
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK.
Nat.Struct.Mol.Biol., 14, 2007
2D85
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BU of 2d85 by Molmil
Solution structure of the fourth CH domain from human L-plastin
Descriptor: L-plastin
Authors:Tomizawa, T, Kigawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-02
Release date:2006-06-02
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the fourth CH domain from human L-plastin
To be Published

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