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2MQF	NMR structure of spider toxin-TRTX-Hhn2b Descriptor: Mu-theraphotoxin-Hhn2b Authors: Klint, J.K, Chin, Y.K.Y, Mobli, M. Deposit date: 2014-06-19 Release date: 2015-07-15 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Rational Engineering Defines a Molecular Switch That Is Essential for Activity of Spider-Venom Peptides against the Analgesics Target NaV1.7 Mol.Pharmacol., 88, 2015
2MPQ	Solution structure of the sodium channel toxin Hd1a Descriptor: Hd1a Authors: Klint, J.K, Mobli, M, King, G.F. Deposit date: 2014-06-01 Release date: 2015-03-25 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Seven novel modulators of the analgesic target NaV 1.7 uncovered using a high-throughput venom-based discovery approach. Br.J.Pharmacol., 172, 2015
2MXM	NMR solution structure of TRTX-Tp1a from the tarantula Thrixopelma pruriens Descriptor: entity Authors: Rosengren, K. Deposit date: 2015-01-08 Release date: 2015-06-03 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Identification and Characterization of ProTx-III [ mu-TRTX-Tp1a], a New Voltage-Gated Sodium Channel Inhibitor from Venom of the Tarantula Thrixopelma pruriens. Mol.Pharmacol., 88, 2015
6W6O	NaChBac-Nav1.7VSDII chimera and HWTX-IV complex Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Huwentoxin-IV, NaChBac-Nav1.7VSDII chimera Authors: Yan, N, Gao, S. Deposit date: 2020-03-17 Release date: 2020-06-24 Last modified: 2021-01-13 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na + channels in nanodisc. Proc.Natl.Acad.Sci.USA, 117, 2020
3J5Q	Structure of TRPV1 ion channel in complex with DkTx and RTX determined by single particle electron cryo-microscopy Descriptor: Kappa-theraphotoxin-Cg1a 1, Transient receptor potential cation channel subfamily V member 1 Authors: Liao, M, Cao, E, Julius, D, Cheng, Y. Deposit date: 2013-10-28 Release date: 2013-12-04 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: TRPV1 structures in distinct conformations reveal activation mechanisms. Nature, 504, 2013
7K48	Structure of NavAb/Nav1.7-VS2A chimera trapped in the resting state by tarantula toxin m3-Huwentoxin-IV Descriptor: Maltose/maltodextrin-binding periplasmic protein,Ion transport protein,Sodium channel protein type 9 subunit alpha chimera, Mu-theraphotoxin-Hs2a Authors: Wisedchaisri, G, Tonggu, L, Gamal El-Din, T.M, McCord, E, Zheng, N, Catterall, W.A. Deposit date: 2020-09-15 Release date: 2020-12-02 Last modified: 2021-01-20 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural Basis for High-Affinity Trapping of the Na V 1.7 Channel in Its Resting State by Tarantula Toxin. Mol.Cell, 81, 2021

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