5DGV
 
 | | Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analog | | Descriptor: | 25S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | | Authors: | Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. | | Deposit date: | 2015-08-28 | | Release date: | 2016-12-14 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
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5DFE
 | | 70S termination complex containing E. coli RF2 | | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | Authors: | Hoffer, E.D, Dunham, C.M. | | Deposit date: | 2015-08-26 | | Release date: | 2016-10-12 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (3.09997559 Å) | | Cite: | Uniformity of Peptide Release Is Maintained by Methylation of Release Factors.
Cell Rep, 17, 2016
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5KCR
 | | Cryo-EM structure of the Escherichia coli 70S ribosome in complex with antibiotic Avilamycin C, mRNA and P-site tRNA at 3.6A resolution | | Descriptor: | (2R,3S,4R,6S)-4-hydroxy-6-{[(2R,3aR,4R,4'R,5'S,6S,6'R,7aR)-4'-hydroxy-6-{[(2S,3R,4R,5S,6R)-3-hydroxy-2-{[(2R,3S,4S,5S,6S)-4-hydroxy-6-({(2R,3aS,3a'R,6S,6'R,7R,7'R,7aR,7a'R)-7'-hydroxy-7'-[(1S)-1-hydroxyethyl]-6'-methyl-7-[(2-methylpropanoyl)oxy]octahydro-4H-2,4'-spirobi[[1,3]dioxolo[4,5-c]pyran]-6-yl}oxy)-5-methoxy-2-(methoxymethyl)tetrahydro-2H-pyran-3-yl]oxy}-5-methoxy-6-methyltetrahydro-2H-pyran-4-yl]oxy}-4,6',7a-trimethyloctahydro-4H-spiro[1,3-dioxolo[4,5-c]pyran-2,2'-pyran]-5'-yl]oxy}-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate (non-preferred name), 16S Ribosomal RNA, 23S Ribosomal RNA, ... | | Authors: | Arenz, S, Juette, M.F, Graf, M, Nguyen, F, Huter, P, Polikanov, Y.S, Blanchard, S.C, Wilson, D.N. | | Deposit date: | 2016-06-06 | | Release date: | 2016-08-17 | | Last modified: | 2019-12-25 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5DC3
 | | Complex of yeast 80S ribosome with non-modified eIF5A | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | Authors: | Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. | | Deposit date: | 2015-08-23 | | Release date: | 2016-06-01 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome.
J.Mol.Biol., 428, 2016
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5D8B
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5KPX
 | | Structure of RelA bound to ribosome in presence of A/R tRNA (Structure IV) | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Loveland, A.B, Bah, E, Madireddy, R, Zhang, Y, Brilot, A.F, Grigorieff, N, Korostelev, A.A. | | Deposit date: | 2016-07-05 | | Release date: | 2016-09-28 | | Last modified: | 2019-11-20 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Ribosome•RelA structures reveal the mechanism of stringent response activation.
Elife, 5, 2016
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6QNQ
 | | 70S ribosome initiation complex (IC) with experimentally assigned potassium ions | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Rozov, A, Khusainov, I, Yusupov, M, Yusupova, G. | | Deposit date: | 2019-02-11 | | Release date: | 2019-06-19 | | Last modified: | 2024-04-24 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Importance of potassium ions for ribosome structure and function revealed by long-wavelength X-ray diffraction.
Nat Commun, 10, 2019
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6QNR
 | | 70S ribosome elongation complex (EC) with experimentally assigned potassium ions | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Rozov, A, Khusainov, I, Yusupov, M, Yusupova, G. | | Deposit date: | 2019-02-11 | | Release date: | 2019-06-19 | | Last modified: | 2024-04-24 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Importance of potassium ions for ribosome structure and function revealed by long-wavelength X-ray diffraction.
Nat Commun, 10, 2019
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5KPV
 | | Structure of RelA bound to ribosome in presence of A/R tRNA (Structure II) | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Loveland, A.B, Bah, E, Madireddy, R, Zhang, Y, Brilot, A.F, Grigorieff, N, Korostelev, A.A. | | Deposit date: | 2016-07-05 | | Release date: | 2016-09-28 | | Last modified: | 2019-11-20 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Ribosome•RelA structures reveal the mechanism of stringent response activation.
Elife, 5, 2016
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6YSU
 | | Structure of the P+0 ArfB-ribosome complex in the post-hydrolysis state | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V. | | Deposit date: | 2020-04-23 | | Release date: | 2020-08-19 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Mechanism of ribosome rescue by alternative ribosome-rescue factor B.
Nat Commun, 11, 2020
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6Z6M
 | | Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1 | | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | Authors: | Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. | | Deposit date: | 2020-05-28 | | Release date: | 2020-07-29 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
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6Z6J
 | | Cryo-EM structure of yeast Lso2 bound to 80S ribosomes under native condition | | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | | Authors: | Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. | | Deposit date: | 2020-05-28 | | Release date: | 2020-07-29 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
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6Z6K
 | | Cryo-EM structure of yeast reconstituted Lso2 bound to 80S ribosomes | | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | | Authors: | Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. | | Deposit date: | 2020-05-28 | | Release date: | 2020-07-29 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
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6Z6N
 | | Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1) | | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | Authors: | Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. | | Deposit date: | 2020-05-28 | | Release date: | 2020-07-29 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
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6ZCE
 | | Structure of a yeast ABCE1-bound 43S pre-initiation complex | | Descriptor: | 18S ribosomal RNA (1719-MER), 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | | Authors: | Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | | Deposit date: | 2020-06-10 | | Release date: | 2020-10-07 | | Last modified: | 2021-01-13 | | Method: | ELECTRON MICROSCOPY (5.3 Å) | | Cite: | A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
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1WF3
 | | Crystal structure of GTP-binding protein TT1341 from Thermus thermophilus HB8 | | Descriptor: | GLYCEROL, GTP-binding protein, MAGNESIUM ION, ... | | Authors: | Kawazoe, M, Hori-Takemoto, C, Kaminishi, T, Sekine, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-05-25 | | Release date: | 2004-11-25 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Crystal structure of GTP-binding protein TT1341 from Thermus thermophilus HB8
To be Published
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4OX9
 | | Crystal structure of the aminoglycoside resistance methyltransferase NpmA bound to the 30S ribosomal subunit | | Descriptor: | 16S rRNA, 16S rRNA (adenine(1408)-N(1))-methyltransferase, 30S ribosomal protein S10, ... | | Authors: | Dunkle, J.A, Conn, G.L, Dunham, C.M. | | Deposit date: | 2014-02-04 | | Release date: | 2014-04-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.8035 Å) | | Cite: | Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA.
Proc.Natl.Acad.Sci.USA, 111, 2014
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1X1L
 | | Interaction of ERA,a GTPase protein, with the 3'minor domain of the 16S rRNA within the THERMUS THERMOPHILUS 30S subunit. | | Descriptor: | GTP-binding protein era, RNA (130-MER) | | Authors: | Sharma, M.R, Barat, C, Agrawal, R.K. | | Deposit date: | 2005-04-06 | | Release date: | 2005-05-17 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (13.5 Å) | | Cite: | Interaction of Era with the 30S Ribosomal Subunit Implications for 30S Subunit Assembly
Mol.Cell, 18, 2005
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4P6F
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4P70
 | | Crystal Structure of Unmodified tRNA Proline (CGG) Bound to Codon CCG on the Ribosome | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Maehigashi, T, Dunkle, J.A, Dunham, C.M. | | Deposit date: | 2014-03-25 | | Release date: | 2014-08-13 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.68 Å) | | Cite: | Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
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1XMO
 | | Crystal Structure of mnm5U34t6A37-tRNALysUUU Complexed with AAG-mRNA in the Decoding Center | | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | Authors: | Murphy, F.V, Ramakrishnan, V, Malkiewicz, A, Agris, P.F. | | Deposit date: | 2004-10-04 | | Release date: | 2004-12-14 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | The role of modifications in codon discrimination by tRNA(Lys)(UUU).
Nat.Struct.Mol.Biol., 11, 2004
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1XNQ
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1XMQ
 | | Crystal Structure of t6A37-ASLLysUUU AAA-mRNA Bound to the Decoding Center | | Descriptor: | 16s ribosomal RNA, 30S Ribosomal Protein S10, 30S Ribosomal Protein S11, ... | | Authors: | Murphy, F.V, Ramakrishnan, V, Malkiewicz, A, Agris, P.F. | | Deposit date: | 2004-10-04 | | Release date: | 2004-12-14 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The role of modifications in codon discrimination by tRNA(Lys)(UUU).
Nat.Struct.Mol.Biol., 11, 2004
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4TUA
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4TUC
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