4OX9

Crystal structure of the aminoglycoside resistance methyltransferase NpmA bound to the 30S ribosomal subunit

Summary for 4OX9

Entry DOI	10.2210/pdb4ox9/pdb
Descriptor	16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... (25 entities in total)
Functional Keywords	protein biosynthesis, ribosome, rna, 30s, 16s, ribosomal subunit, aminoglycoside, a1408, methyltransferase, ribosome-antibiotic complex, ribosome/antibiotic
Biological source	Escherichia coli More
Total number of polymer chains	22
Total formula weight	807959.84
Authors	Dunkle, J.A.,Conn, G.L.,Dunham, C.M. (deposition date: 2014-02-04, release date: 2014-04-09, Last modification date: 2023-09-27)
Primary citation	Dunkle, J.A.,Vinal, K.,Desai, P.M.,Zelinskaya, N.,Savic, M.,West, D.M.,Conn, G.L.,Dunham, C.M. Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA. Proc.Natl.Acad.Sci.USA, 111:6275-6280, 2014 Cited by PubMed: 24717845 DOI: 10.1073/pnas.1402789111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.8035 Å)

Structure validation