PDB: 65 resultsInfo pagesStatus searchChemie searchBIRD

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5Y04	Crystal Structure of the complex between the vinculin D1 domain and alphaE-catenin Descriptor: Catenin alpha-1, Vinculin Authors: Hirano, Y, Hakoshima, T. Deposit date: 2017-07-14 Release date: 2018-03-28 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2.85 Å) Cite: The force-sensing device region of alpha-catenin is an intrinsically disordered segment in the absence of intramolecular stabilization of the autoinhibitory form Genes Cells, 23, 2018
6BFI	Vinculin homolog in a sponge (phylum Porifera) reveals vertebrate-like cell adhesions involved in early multicellular evolution Descriptor: VIN1 Authors: Weis, W.I, Chodaparambil, J.V. Deposit date: 2017-10-26 Release date: 2018-06-13 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Analysis of a vinculin homolog in a sponge (phylum Porifera) reveals that vertebrate-like cell adhesions emerged early in animal evolution. J. Biol. Chem., 293, 2018
6DUW	Crystal structure of the alpha-N-catenin actin-binding domain H1 mutant Descriptor: Catenin alpha-2 Authors: Ishiyama, N, Ikura, M. Deposit date: 2018-06-22 Release date: 2018-12-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Force-dependent allostery of the alpha-catenin actin-binding domain controls adherens junction dynamics and functions. Nat Commun, 9, 2018
6DUY	Crystal structure of the alpha-N-catenin actin-binding domain H1 mutant Descriptor: Catenin alpha-2 Authors: Ishiyama, N, Ikura, M. Deposit date: 2018-06-22 Release date: 2018-12-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.81 Å) Cite: Force-dependent allostery of the alpha-catenin actin-binding domain controls adherens junction dynamics and functions. Nat Commun, 9, 2018
6FQ4	Structure of Chlamydial virulence factor TarP and vinculin head domain Descriptor: TarP-VBS1, Vinculin Authors: Whitewood, A.J, Singh, A.K, Brown, D.G, Goult, B.T. Deposit date: 2018-02-13 Release date: 2018-05-09 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.89 Å) Cite: Chlamydial virulence factor TarP mimics talin to disrupt the talin-vinculin complex. FEBS Lett., 592, 2018
6FUY	Crystal structure of human full-length vinculin-T12-A974K (residues 1-1066) Descriptor: CALCIUM ION, Vinculin Authors: Chorev, D.S, Volberg, T, Livne, A, Eisenstein, M, Martins, B, Kam, Z, Jockusch, B.M, Medalia, O, Sharon, M, Geiger, B. Deposit date: 2018-02-28 Release date: 2018-03-14 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3 Å) Cite: Conformational states during vinculin unlocking differentially regulate focal adhesion properties. Sci Rep, 8, 2018
6NR7	Rerefinement of chicken vinculin Descriptor: (1R,2R,3S,4R,5R,6S)-4-{[(S)-[(2S)-2,3-dihydroxypropoxy](hydroxy)phosphoryl]oxy}-3,5,6-trihydroxycyclohexane-1,2-diyl bis[dihydrogen (phosphate)], PHOSPHATE ION, SULFATE ION, ... Authors: Stec, B. Deposit date: 2019-01-23 Release date: 2020-01-29 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3 Å) Cite: Refined model of chicken vinculin suggests the mechanism of activation by helical super-bundle unfurling To be published
6O3E	mouse aE-catenin 82-883 Descriptor: Catenin alpha-1 Authors: Pokutta, S, Weis, W.I. Deposit date: 2019-02-26 Release date: 2019-11-13 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (4.001 Å) Cite: Binding partner- and force-promoted changes in alpha E-catenin conformation probed by native cysteine labeling. Sci Rep, 9, 2019
6UPV	Alpha-E-catenin ABD-F-actin complex Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... Authors: Mei, L, Alushin, G.M. Deposit date: 2019-10-18 Release date: 2020-09-30 Last modified: 2020-10-07 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Molecular mechanism for direct actin force-sensing by alpha-catenin. Elife, 9, 2020
6UPW	Metavinculin ABD-F-actin complex Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... Authors: Mei, L, Alushin, G.M. Deposit date: 2019-10-18 Release date: 2020-09-30 Last modified: 2020-10-07 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Molecular mechanism for direct actin force-sensing by alpha-catenin. Elife, 9, 2020
7KTT	Cryogenic electron microscopy model of full-length human metavinculin Descriptor: metavinculin Authors: Izard, T, Rangarajan, E.S. Deposit date: 2020-11-24 Release date: 2021-01-27 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (4.17 Å) Cite: The Cryogenic Electron Microscopy Structure of the Cell Adhesion Regulator Metavinculin Reveals an Isoform-Specific Kinked Helix in Its Cytoskeleton Binding Domain. Int J Mol Sci, 22, 2021
7KTU	Cryogenic electron microscopy model of full-length human metavinculin H1'-parallel conformation 1 Descriptor: metavinculin Authors: Izard, T, Rangarajan, E.S. Deposit date: 2020-11-24 Release date: 2021-01-27 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (4.15 Å) Cite: The Cryogenic Electron Microscopy Structure of the Cell Adhesion Regulator Metavinculin Reveals an Isoform-Specific Kinked Helix in Its Cytoskeleton Binding Domain. Int J Mol Sci, 22, 2021
7KTV	Cryogenic electron microscopy model of full-length human metavinculin H1' kinked conformation Descriptor: metavinculin Authors: Izard, T, Rangarajan, E.S. Deposit date: 2020-11-24 Release date: 2021-01-27 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: The Cryogenic Electron Microscopy Structure of the Cell Adhesion Regulator Metavinculin Reveals an Isoform-Specific Kinked Helix in Its Cytoskeleton Binding Domain. Int J Mol Sci, 22, 2021
7KTW	Cryogenic electron microscopy model of full-length human metavinculin H1'-parallel conformation 2 Descriptor: metavinculin Authors: Izard, T, Rangarajan, E.S. Deposit date: 2020-11-24 Release date: 2021-01-27 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (4.27 Å) Cite: The Cryogenic Electron Microscopy Structure of the Cell Adhesion Regulator Metavinculin Reveals an Isoform-Specific Kinked Helix in Its Cytoskeleton Binding Domain. Int J Mol Sci, 22, 2021
7UTJ	Cryogenic electron microscopy 3D map of F-actin bound by human dimeric alpha-catenin Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... Authors: Rangarajan, E.S, Smith, E.W, Izard, T. Deposit date: 2022-04-27 Release date: 2023-03-08 Last modified: 2023-03-29 Method: ELECTRON MICROSCOPY (2.77 Å) Cite: Distinct inter-domain interactions of dimeric versus monomeric alpha-catenin link cell junctions to filaments. Commun Biol, 6, 2023

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