PDB: 430 resultsInfo pagesStatus searchChemie searchBIRD

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6R75	Crystal structure of human Ube2T E54R mutant Descriptor: Ubiquitin-conjugating enzyme E2 T Authors: Chaugule, V.K, Rennie, M.L, Walden, H, Arkinson, C, Kamarainen, O, Toth, R. Deposit date: 2019-03-28 Release date: 2019-10-16 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2 Å) Cite: Allosteric mechanism for site-specific ubiquitination of FANCD2. Nat.Chem.Biol., 16, 2020
5A4P	Structure of UBE2Z provides functional insight into specificity in the FAT10 conjugation machinery Descriptor: DI(HYDROXYETHYL)ETHER, MALONATE ION, UBIQUITIN-CONJUGATING ENZYME E2 Z Authors: Schelpe, J, Monte, D, Dewitte, F, Sixma, T.K, Rucktooa, P. Deposit date: 2015-06-11 Release date: 2015-11-18 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure of Ube2Z Provides Functional Insight Into Specificity in the Fat10 Conjugation Machinery J.Biol.Chem., 291, 2016
6Q83	Crystal structure of the biportin Pdr6 in complex with UBC9 Descriptor: Importin beta-like protein KAP122, UBC9 Authors: Aksu, M, Trakhanov, S, Vera-Rodriguez, A, Gorlich, D. Deposit date: 2018-12-14 Release date: 2019-05-01 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (4.53 Å) Cite: Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122. J.Cell Biol., 218, 2019
6QH3	Catalytic domain of the human ubiquitin-conjugating enzyme UBE2S C118M Descriptor: 1,2-ETHANEDIOL, Ubiquitin-conjugating enzyme E2 S Authors: Liess, A.K.L, Lorenz, S. Deposit date: 2019-01-15 Release date: 2019-07-17 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S by Autoubiquitination. Structure, 27, 2019
6S98	Crystal structure of the catalytic domain of UBE2S WT. Descriptor: 1,2-ETHANEDIOL, ACETATE ION, SODIUM ION, ... Authors: Liess, A.K.L, Lorenz, S. Deposit date: 2019-07-11 Release date: 2020-10-21 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S. Sci.Signal., 13, 2020
6S96	Crystal structure of the catalytic domain of UBE2S C118A. Descriptor: FORMIC ACID, SODIUM ION, Ubiquitin-conjugating enzyme E2 S Authors: Liess, A.K.L, Lorenz, S. Deposit date: 2019-07-11 Release date: 2020-10-21 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.18 Å) Cite: Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S. Sci.Signal., 13, 2020
4DS2	Ubiquitin conjugating enzyme (putative) from Trypanosoma cruzi Descriptor: Ubiquitin-conjugating enzyme E2, putative Authors: Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) Deposit date: 2012-02-17 Release date: 2012-02-29 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.63 Å) Cite: Ubiquitin conjugating enzyme (putative) from Trypanosoma cruzi To be Published
4FH1	S. cerevisiae Ubc13-N79A Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Ubiquitin-conjugating enzyme E2 13 Authors: Berndsen, C.E, Wolberger, C, Wiener, R. Deposit date: 2012-06-05 Release date: 2013-01-09 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.61 Å) Cite: A conserved asparagine has a structural role in ubiquitin-conjugating enzymes. Nat.Chem.Biol., 9, 2013
4GPR	Crystal structure of EhUbc5, a ubiquitin conjugating enzyme from Entamoeba histolytica Descriptor: COBALT (II) ION, Ubiquitin-conjugating enzyme family protein Authors: Bosch, D.E, Siderovski, D.P. Deposit date: 2012-08-21 Release date: 2012-12-12 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural Determinants of Ubiquitin Conjugation in Entamoeba histolytica. J.Biol.Chem., 288, 2013
6CYO	Crystal structure of human UBE2A (RAD6A) Descriptor: Ubiquitin-conjugating enzyme E2 A Authors: Ranzani, A.T, de Oliveira, J.F. Deposit date: 2018-04-06 Release date: 2018-12-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Mechanistic insights revealed by a UBE2A mutation linked to intellectual disability. Nat. Chem. Biol., 15, 2019
6SYF	Human Ubc9 with covalent isopeptide ligand Descriptor: ACE-ILE-LYS-GLN-GLU, ACE-LEU-ARG-LEU-ARG-GLY-CYS, SUMO-conjugating enzyme UBC9 Authors: Hofmann, R, Akimoto, G, Wucherpfennig, T.G, Zeymer, C, Bode, J.W. Deposit date: 2019-09-27 Release date: 2020-08-12 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Lysine acylation using conjugating enzymes for site-specific modification and ubiquitination of recombinant proteins. Nat.Chem., 12, 2020
6CYR	Crystal structure of the UBE2A variant Q93E Descriptor: Ubiquitin-conjugating enzyme E2 A Authors: Ranzani, A.T, de Oliveira, J.F. Deposit date: 2018-04-06 Release date: 2018-12-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Mechanistic insights revealed by a UBE2A mutation linked to intellectual disability. Nat. Chem. Biol., 15, 2019
3TGD	Crystal structure of the human ubiquitin-conjugating enzyme (E2) UbcH5b Descriptor: Ubiquitin-conjugating enzyme E2 D2 Authors: Page, R.C, Amick, J, Misra, S. Deposit date: 2011-08-17 Release date: 2011-08-31 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of the human ubiquitin-conjugating enzyme (E2) UbcH5b To be Published
6MJ9	CRYSTAL STRUCTURE OF UBIQUITIN-CONJUGATING ENZYME FROM NAEGLERIA FOWLERI, APO FORM Descriptor: Ubiquitin-conjugating enzyme Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-09-20 Release date: 2018-10-10 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.85 Å) Cite: CRYSTAL STRUCTURE OF UBIQUITIN-CONJUGATING ENZYME FROM NAEGLERIA FOWLERI, APO FORM To Be Published
3WE5	Crystal structure of ubiquitin conjugating enzyme E2 UbcA1 from Agrocybe aegerita Descriptor: ACETIC ACID, GLYCEROL, Ubiquitin conjugating enzyme Authors: Li, D.F, Feng, L, Wang, D.C, Liu, W. Deposit date: 2013-07-01 Release date: 2014-07-09 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structure of ubiquitin conjugating enzyme E2 UbcA1 from Agrocybe aegerita To be Published
4ONM	Crystal structure of human Mms2/Ubc13 - NSC697923 Descriptor: 2-[(4-methylphenyl)sulfonyl]-5-nitrofuran, GLYCEROL, Ubiquitin-conjugating enzyme E2 N, ... Authors: Hodge, C.D, Edwards, R.A, Glover, J.N.M. Deposit date: 2014-01-28 Release date: 2015-05-06 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting. Acs Chem.Biol., 10, 2015
4M1N	Crystal structure of Plasmodium falciparum ubiquitin conjugating enzyme UBC9 Descriptor: SODIUM ION, Ubiquitin conjugating enzyme UBC9 Authors: Boucher, L.E, Reiter, K.H, Bosch, J, Matunis, J.M. Deposit date: 2013-08-03 Release date: 2013-08-21 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Identification of Biochemically Distinct Properties of the Small Ubiquitin-related Modifier (SUMO) Conjugation Pathway in Plasmodium falciparum. J.Biol.Chem., 288, 2013
4ONN	Crystal structure of human Mms2/Ubc13 - BAY 11-7082 Descriptor: 3-[(4-methylphenyl)sulfonyl]prop-2-enenitrile, GLYCEROL, Ubiquitin-conjugating enzyme E2 N, ... Authors: Hodge, C.D, Edwards, R.A, Glover, J.N.M. Deposit date: 2014-01-28 Release date: 2015-05-06 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting. Acs Chem.Biol., 10, 2015
5V0R	Crystal structure of ubiquitin-conjugating enzyme from Naegleria fowleri with modified Cys99 Descriptor: CHLORIDE ION, MAGNESIUM ION, Ubiquitin-conjugating enzyme Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2017-02-28 Release date: 2017-03-29 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Crystal structure of ubiquitin-conjugating enzyme from Naegleria fowleri with modified Cys99 to be published
4NR3	Crystal Structure of a human Mms2/Ubc13 L121G mutant Descriptor: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2 Authors: Hodge, C.D, Edwards, R.A, Glover, J.N.M. Deposit date: 2013-11-26 Release date: 2014-12-10 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.802 Å) Cite: Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes. J.Am.Chem.Soc., 136, 2014
4NRI	Crystal Structure of a human Mms2/Ubc13 A122G mutant Descriptor: GLYCEROL, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2 Authors: Hodge, C.D, Edwards, R.A, Glover, J.N.M. Deposit date: 2013-11-26 Release date: 2014-12-10 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes. J.Am.Chem.Soc., 136, 2014
4NRG	Crystal Structure of a human Mms2/Ubc13 D118G mutant Descriptor: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2 Authors: Hodge, C.D, Edwards, R.A, Glover, J.N.M. Deposit date: 2013-11-26 Release date: 2014-12-10 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes. J.Am.Chem.Soc., 136, 2014
4ONL	Crystal structure of human Mms2/Ubc13_D81N, R85S, A122V, N123P Descriptor: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2 Authors: Hodge, C.D, Edwards, R.A, Glover, J.N.M. Deposit date: 2014-01-28 Release date: 2015-05-06 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting. Acs Chem.Biol., 10, 2015
2YB6	Native human Rad6 Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, UBIQUITIN-CONJUGATING ENZYME E2 B Authors: Hibbert, R.G, Sixma, T.K. Deposit date: 2011-03-02 Release date: 2011-04-20 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: E3 Ligase Rad18 Promotes Monoubiquitination Rather Than Ubiquitin Chain Formation by E2 Enzyme Rad6. Proc.Natl.Acad.Sci.USA, 108, 2011
2YBF	Complex of Rad18 (Rad6 binding domain) with Rad6b Descriptor: BETA-MERCAPTOETHANOL, E3 UBIQUITIN-PROTEIN LIGASE RAD18, SODIUM ION, ... Authors: Hibbert, R.G, Sixma, T.K. Deposit date: 2011-03-08 Release date: 2011-04-20 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2 Å) Cite: E3 Ligase Rad18 Promotes Monoubiquitination Rather Than Ubiquitin Chain Formation by E2 Enzyme Rad6. Proc.Natl.Acad.Sci.USA, 108, 2011

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